HSPB8 ELISA Kit for Human(Homo sapiens) | EIAab.comHSPB8 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > HSPB8(Gene name) > Human

HSPB8 (Gene name),

Heat shock protein beta-8 (Protein name ), HSPB8_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

HSPB8(PP1629;CRYAC;E2IG1;HSP22);

Protein name:

Heat shock protein beta-8(HspB8);

Alternative:

E2-induced gene 1 protein;Alpha-crystallin C chain;Small stress protein-like protein HSP22;Protein kinase H11;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer. Interacts with HSPB1.

Function:

Displays temperature-dependent chaperone activity.

Subcellular Location:

Cytoplasm Nucleus Translocates to nuclear foci during heat shock.

Protein Attributes:

Sequence length:

196

Sequence:

50:

100:

150:

196:

PVTVFASLSP | EGLLIIEAPQ | VPPYSTFGES | SFNNELPQDS | QEVTCT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9UJY1

MIM:

158590

STRING:

9606.ENSP00000281938

Pfam:

PF00011

SMR:

Q9UJY1

UniGene:

Hs.400095

KEGG:

hsa:26353

Uniprot:

Q9UJY1

FOR

ELISA Kit for Human HspB8

CLIA Kit for Human HspB8

Polyclonal Antibody for Human HspB8

Monoclonal Antibody for Human HspB8

Protein for Human HspB8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Effects of estrogen on global gene expression: identification of novel targets of estrogen action."
Charpentier A.H. , Bednarek A.K. , Daniel R.L. , Hawkins K.A. , Laflin K.J. , Gaddis S. , MacLeod M.C. , Aldaz C.M.
Cancer Res.60:5977-5983(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 (3DHSP27)."
Benndorf R. , Sun X. , Gilmont R.R. , Biederman K.J. , Molloy M.P. , Goodmurphy C.W. , Cheng H. , Andrews P.C. , Welsh M.J.
J. Biol. Chem.276:26753-26761(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH HSPB1
3.

"A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells."
Smith C.C. , Yu Y.X. , Kulka M. , Aurelian L.
J. Biol. Chem.275:25690-25699(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Melanoma.
4.

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S. , Weil B. , Wellenreuther R. , Gassenhuber J. , Glassl S. , Ansorge W. , Boecher M. , Bloecker H. , Bauersachs S. , Blum H. , Lauber J. , Duesterhoeft A. , Beyer A. , Koehrer K. , Strack N. , Mewes H.-W. , Ottenwaelder B. , Obermaier B. , more...
Genome Res.11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Uterus.
5.

"Large-scale cDNA transfection screening for genes related to cancer development and progression."
Wan D. , Gong Y. , Qin W. , Zhang P. , Li J. , Wei L. , Zhou X. , Li H. , Qiu X. , Zhong F. , He L. , Yu J. , Yao G. , Jiang H. , Qian L. , Yu Y. , Shu H. , Chen X. , more...
Proc. Natl. Acad. Sci. U.S.A.101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
8.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Thalamus.
9.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Uterus.
11.

"Phosphopeptide derivatization signatures to identify serine and threonine phosphorylated peptides by mass spectrometry."
Molloy M.P. , Andrews P.C.
Anal. Chem.73:5387-5394(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-63;IDENTIFICATION BY MASS SPECTROMETRY
12.

"Characterization of two novel human small heat shock proteins: protein kinase-related HspB8 and testis-specific HspB9."
Kappe G. , Verschuure P. , Philipsen R.L.A. , Staalduinen A.A. , Van de Boogaart P. , Boelens W.C. , de Jong W.W.
Biochim. Biophys. Acta1520:1-6(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
13.

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-24;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-24;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
15.

"HSPB7 is a SC35 speckle resident small heat shock protein."
Vos M.J. , Kanon B. , Kampinga H.H.
Biochim. Biophys. Acta1793:1343-1353(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
16.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
17.

"Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy."
Sarparanta J. , Jonson P.H. , Golzio C. , Sandell S. , Luque H. , Screen M. , McDonald K. , Stajich J.M. , Mahjneh I. , Vihola A. , Raheem O. , Penttila S. , Lehtinen S. , Huovinen S. , Palmio J. , Tasca G. , Ricci E. , Hackman P. , more...
Nat. Genet.44:450-455(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNAJB6
18.

"Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy."
Irobi J. , Van Impe K. , Seeman P. , Jordanova A. , Dierick I. , Verpoorten N. , Michalik A. , De Vriendt E. , Jacobs A. , Van Gerwen V. , Vennekens K. , Mazanec R. , Tournev I. , Hilton-Jones D. , Talbot K. , Kremensky I. , Van Den Bosch L. , Robberecht W. , more...
Nat. Genet.36:597-601(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HMN2A GLU-141 AND ASN-141
19.

"Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L."
Tang B.-S. , Zhao G.-H. , Luo W. , Xia K. , Cai F. , Pan Q. , Zhang R.-X. , Zhang F.F. , Liu X.-M. , Chen B. , Zhang C. , Shen L. , Jiang H. , Long Z.G. , Dai H.-P.
Hum. Genet.116:222-224(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMT2L ASN-141
20.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] SER-67 AND MET-78

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