Nfkbib ELISA Kit for Rat(Rattus norvegicus) | EIAab.comNfkbib ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Nfkbib(Gene name) > Rat

Nfkbib (Gene name),

NF-kappa-B inhibitor beta (Protein name ), IKBB_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

Nfkbib(Ikbb);

Protein name:

NF-kappa-B inhibitor beta(NF-kappa-BIB);

Alternative:

I-kappa-B-beta(IkB-B;IkB-beta;IkappaBbeta);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with COMMD1 and inhibitor kappa B-interacting Ras-like NKIRAS1 and NKIRAS2 (By similarity). Interacts with THRB (via ligand-binding domain). Interacts with RELA and REL.

Function:

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

359

Sequence:

50:

100:

150:

200:

250:

300:

350:

359:

PLPDDPNPA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9JIA3

String:

Q9JIA3

UniGene:

Rn.8395

Pfam:

PF12796

Uniprot:

Q9JIA3

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ELISA Kit for Rat NF-kappa-BIB

Cat.:

E1849h

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Manual:

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Packing:

96T

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ELISA Kit for Rat NF-kappa-BIB

Cat.:

E1849r

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Packing:

96T

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ELISA Kit for Rat NF-kappa-BIB

Cat.:

E1849m

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MSDS:

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Packing:

96T

CLIA Kit for Rat NF-kappa-BIB

Cat.:

U1849m

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MSDS:

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Packing:

96T

CLIA Kit for Rat NF-kappa-BIB

Cat.:

U1849h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat NF-kappa-BIB

Cat.:

U1849r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat NF-kappa-BIB

Cat.:

P1849Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat NF-kappa-BIB

Cat.:

P1849Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat NF-kappa-BIB

Cat.:

P1849Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat NF-kappa-BIB

Protein for Rat NF-kappa-BIB

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Sitagliptin attenuates transient cerebral ischemia/reperfusion injury in diabetic rats: Implication of the oxidative–inflammatory–apoptotic pathway"

AE El-Sahar, MM Safar, HF Zaki, et al.

From:Life Sciences

References

1.

"Ribosomal S6 kinase-1 modulates interleukin-1beta-induced persistent activation of NF-kappaB through phosphorylation of IkappaBbeta."
Xu S. , Bayat H. , Hou X. , Jiang B.
Am. J. Physiol.291:C1336-C1345(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-19 AND SER-23
2.

"Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide synthase type 2 in brain glial cells: the role of I kappa B-beta."
Stasiolek M. , Gavrilyuk V. , Sharp A. , Horvath P. , Selmaj K. , Feinstein D.L.
J. Biol. Chem.275:24847-24856(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION

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