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Index > Protein center > IRX3(Gene name) > Human
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  • IRX3 (Gene name),
  • Iroquois-class homeodomain protein IRX-3 (Protein name ),  IRX3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    IRX3(IRXB1);
    Protein name:
    Iroquois-class homeodomain protein IRX-3;
    Alternative:
    Iroquois homeobox protein 3;Homeodomain protein IRXB1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    501
    Sequence:
    50:
    MSFPQLGYQY | IRPLYPSERP | GAAGGSGGSA | GARGGLGAGA | SELNASGSLS | 
    100:
    NVLSSVYGAP | YAAAAAAAAA | QGYGAFLPYA | AELPIFPQLG | AQYELKDSPG | 
    150:
    VQHPAAAAAF | PHPHPAFYPY | GQYQFGDPSR | PKNATRESTS | TLKAWLNEHR | 
    200:
    KNPYPTKGEK | IMLAIITKMT | LTQVSTWFAN | ARRRLKKENK | MTWAPRSRTD | 
    250:
    EEGNAYGSER | EEEDEEEDEE | DGKRELELEE | EELGGEEEDT | GGEGLADDDE | 
    300:
    DEEIDLENLD | GAATEPELSL | AGAARRDGDL | GLGPISDSKN | SDSEDSSEGL | 
    350:
    EDRPLPVLSL | APAPPPVAVA | SPSLPSPPVS | LDPCAPAPAP | ASALQKPKIW | 
    400:
    SLAETATSPD | NPRRSPPGAG | GSPPGAAVAP | SALQLSPAAA | AAAAHRLVSA | 
    450:
    PLGKFPAWTN | RPFPGPPPGP | RLHPLSLLGS | APPHLLGLPG | AAGHPAAAAA | 
    500:
    FARPAEPEGG | TDRCSALEVE | KKLLKTAFQP | VPRRPQNHLD | AALVLSALSS | 
    501:
    S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    KEGG:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Iroquois-class homeodomain protein IRX-3
    ELISA Kit for Human Iroquois-class homeodomain protein IRX-3
    CLIA Kit for Human Iroquois-class homeodomain protein IRX-3
    CLIA Kit for Human Iroquois-class homeodomain protein IRX-3
    Polyclonal Antibody for Human Iroquois-class homeodomain protein IRX-3
    Polyclonal Antibody for Human Iroquois-class homeodomain protein IRX-3
    Monoclonal Antibody for Human Iroquois-class homeodomain protein IRX-3
    Monoclonal Antibody for Human Iroquois-class homeodomain protein IRX-3
    Protein for Human Iroquois-class homeodomain protein IRX-3
    Protein for Human Iroquois-class homeodomain protein IRX-3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Characterization of the human homeobox two-cluster Iroquois gene family."
      Hansen L. , Wu Q. , Tommerup N.
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PRO-422
      tissue: Muscle.
    3. 3.
      "IRX: a new family of human homeobox genes from the breast."
      Lewis M.T. , Strickland P.A. , Ross S. , Snyder C.J. , Daniel C.W.
      Submitted (1997-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 91-176
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