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Index > Protein center > Itm2b(Gene name) > Mouse
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  • Itm2b (Gene name),
  • Integral membrane protein 2B (Protein name ),  ITM2B_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Itm2b;
    Protein name:
    Integral membrane protein 2B;
    Alternative:
    Protein E25B;Protein E25B(imBRI2);Transmembrane protein BRI(Bri);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with SPPL2A and SPPL2B. Interacts with APP.
    Function:
    Functions as a protease inhibitor. Plays a role in APP processing regulating the physiological production of the beta amyloid peptide. Restricts docking of gamma-secretase to APP and access of alpha- and beta-secretase to their cleavage APP sequence.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein Cell membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    266
    Sequence:
    50:
    MVKVTFNSAL | AQKEAKKDEP | KSSEEALIVP | PDAVAVDCKD | PGDVVPVGQR | 
    100:
    RAWCWCMCFG | LAFMLAGVIL | GGAYLYKYFA | LQPDDVYYCG | LKYIKDDVIL | 
    150:
    NEPSADAPAA | RYQTIEENIK | IFEEDAVEFI | SVPVPEFADS | DPANIVHDFN | 
    200:
    KKLTAYLDLN | LDKCYVIPLN | TSIVMPPKNL | LELLINIKAG | TYLPQSYLIH | 
    250:
    EHMVITDRIE | NVDNLGFFIY | RLCHDKETYK | LQRRETIRGI | QKREASNCFT | 
    266:
    IRHFENKFAV | ETLICS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Integral membrane protein 2B
    ELISA Kit for Mouse Integral membrane protein 2B
    ELISA Kit for Mouse Integral membrane protein 2B
    ELISA Kit for Mouse Integral membrane protein 2B
    ELISA Kit for Mouse Integral membrane protein 2B
    ELISA Kit for Mouse Integral membrane protein 2B
    CLIA Kit for Mouse Integral membrane protein 2B
    CLIA Kit for Mouse Integral membrane protein 2B
    CLIA Kit for Mouse Integral membrane protein 2B
    CLIA Kit for Mouse Integral membrane protein 2B
    CLIA Kit for Mouse Integral membrane protein 2B
    CLIA Kit for Mouse Integral membrane protein 2B
    Polyclonal Antibody for Mouse Integral membrane protein 2B
    Polyclonal Antibody for Mouse Integral membrane protein 2B
    Polyclonal Antibody for Mouse Integral membrane protein 2B
    Polyclonal Antibody for Mouse Integral membrane protein 2B
    Polyclonal Antibody for Mouse Integral membrane protein 2B
    Polyclonal Antibody for Mouse Integral membrane protein 2B
    Monoclonal Antibody for Mouse Integral membrane protein 2B
    Monoclonal Antibody for Mouse Integral membrane protein 2B
    Monoclonal Antibody for Mouse Integral membrane protein 2B
    Monoclonal Antibody for Mouse Integral membrane protein 2B
    Monoclonal Antibody for Mouse Integral membrane protein 2B
    Monoclonal Antibody for Mouse Integral membrane protein 2B
    Protein for Mouse Integral membrane protein 2B
    Protein for Mouse Integral membrane protein 2B
    Protein for Mouse Integral membrane protein 2B
    Protein for Mouse Integral membrane protein 2B
    Protein for Mouse Integral membrane protein 2B
    Protein for Mouse Integral membrane protein 2B

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    References
    1. 1.
      "cDNA sequence analysis, chromosomal assignment and expression pattern of the gene coding for integral membrane protein 2B."
      Pittois K. , Deleersnijder W. , Merregaert J.
      Gene217:141-149(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains."
      Inoue S. , Sano H. , Ohta M.
      Biochem. Biophys. Res. Commun.268:553-561(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Cerebellum.
      tissue: Head.
      tissue: Hippocampus.
      tissue: Kidney.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary gland.
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