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Index > Protein center > PRKD3(Gene name) > Human
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  • PRKD3 (Gene name),
  • Serine/threonine-protein kinase D3 (Protein name ),  KPCD3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PRKD3(EPK2;PRKCN);
    Protein name:
    Serine/threonine-protein kinase D3;
    Alternative:
    Protein kinase EPK2;Protein kinase C nu type;nPKC-nu;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
    Subcellular Location:
    Cytoplasm Membrane Translocation to the cell membrane is required for kinase activation.
    Protein Attributes:
    Sequence length:
    890
    Sequence:
    50:
    MSANNSPPSA | QKSVLPTAIP | AVLPAASPCS | SPKTGLSARL | SNGSFSAPSL | 
    100:
    TNSRGSVHTV | SFLLQIGLTR | ESVTIEAQEL | SLSAVKDLVC | SIVYQKFPEC | 
    150:
    GFFGMYDKIL | LFRHDMNSEN | ILQLITSADE | IHEGDLVEVV | LSALATVEDF | 
    200:
    QIRPHTLYVH | SYKAPTFCDY | CGEMLWGLVR | QGLKCEGCGL | NYHKRCAFKI | 
    250:
    PNNCSGVRKR | RLSNVSLPGP | GLSVPRPLQP | EYVALPSEES | HVHQEPSKRI | 
    300:
    PSWSGRPIWM | EKMVMCRVKV | PHTFAVHSYT | RPTICQYCKR | LLKGLFRQGM | 
    350:
    QCKDCKFNCH | KRCASKVPRD | CLGEVTFNGE | PSSLGTDTDI | PMDIDNNDIN | 
    400:
    SDSSRGLDDT | EEPSPPEDKM | FFLDPSDLDV | ERDEEAVKTI | SPSTSNNIPL | 
    450:
    MRVVQSIKHT | KRKSSTMVKE | GWMVHYTSRD | NLRKRHYWRL | DSKCLTLFQN | 
    500:
    ESGSKYYKEI | PLSEILRISS | PRDFTNISQG | SNPHCFEIIT | DTMVYFVGEN | 
    550:
    NGDSSHNPVL | AATGVGLDVA | QSWEKAIRQA | LMPVTPQASV | CTSPGQGKDH | 
    600:
    KDLSTSISVS | NCQIQENVDI | STVYQIFADE | VLGSGQFGIV | YGGKHRKTGR | 
    650:
    DVAIKVIDKM | RFPTKQESQL | RNEVAILQNL | HHPGIVNLEC | MFETPERVFV | 
    700:
    VMEKLHGDML | EMILSSEKSR | LPERITKFMV | TQILVALRNL | HFKNIVHCDL | 
    750:
    KPENVLLASA | EPFPQVKLCD | FGFARIIGEK | SFRRSVVGTP | AYLAPEVLRS | 
    800:
    KGYNRSLDMW | SVGVIIYVSL | SGTFPFNEDE | DINDQIQNAA | FMYPPNPWRE | 
    850:
    ISGEAIDLIN | NLLQVKMRKR | YSVDKSLSHP | WLQDYQTWLD | LREFETRIGE | 
    890:
    RYITHESDDA | RWEIHAYTHN | LVYPKHFIMA | PNPDDMEEDP | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    String:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Serine/threonine-protein kinase D3
    ELISA Kit for Human Serine/threonine-protein kinase D3
    CLIA Kit for Human Serine/threonine-protein kinase D3
    CLIA Kit for Human Serine/threonine-protein kinase D3
    Polyclonal Antibody for Human Serine/threonine-protein kinase D3
    Polyclonal Antibody for Human Serine/threonine-protein kinase D3
    Monoclonal Antibody for Human Serine/threonine-protein kinase D3
    Monoclonal Antibody for Human Serine/threonine-protein kinase D3
    Protein for Human Serine/threonine-protein kinase D3
    Protein for Human Serine/threonine-protein kinase D3

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu."
      Hayashi A. , Seki N. , Hattori A. , Kozuma S. , Saito T.
      Biochim. Biophys. Acta1450:99-106(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Embryo.
    2. 2.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS THR-128 AND ARG-546
      tissue: Testis.
    6. 6.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-364;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family."
      Chen J. , Deng F. , Li J. , Wang Q.J.
      Biochem. J.411:333-342(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;SUBCELLULAR LOCATION;PHORBOL-ESTER BINDING;MUTAGENESIS OF THR-156; TYR-158; PRO-165; THR-166; TYR-170; PRO-282 AND LYS-293
    8. 8.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-6; SER-27; SER-37; SER-41; SER-213; SER-216; SER-364 AND THR-535;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-27; SER-41; SER-44 AND SER-364;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-27; SER-41; SER-213; SER-216; SER-364 AND THR-535;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-27; SER-41 AND SER-44;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      "Solution structure of the PH domain of protein kinase C, nu type from human."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2007-01) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 414-532
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