MMP1 ELISA Kit for Human(Homo sapiens) | EIAab.comMMP1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MMP1(Gene name) > Human

MMP1 (Gene name),

Interstitial collagenase (Protein name ), MMP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

MMP1(CLG);

Protein name:

Interstitial collagenase;

Alternative:

Matrix metalloproteinase-1(MMP-1);Fibroblast collagenase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with HIV-1 Tat.

Function:

Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

469

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

469:

TKRILTLQKA | NSWFNCRKN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.83169

String:

P03956

STRING:

9606.ENSP00000322788

KEGG:

hsa:4312

Pfam:

PF00045

MIM:

120353

SMR:

P03956

Uniprot:

P03956

FOR

ELISA Kit for Human Interstitial collagenase

Cat.:

E0097b

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96T

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ELISA Kit for Human Interstitial collagenase

Cat.:

E0097h

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96T

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ELISA Kit for Human Interstitial collagenase

Cat.:

E0097r

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96T

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ELISA Kit for Human Interstitial collagenase

MSDS:

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ELISA Kit for Human Interstitial collagenase

Cat.:

E0097p

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Packing:

96T

CLIA Kit for Human Interstitial collagenase

MSDS:

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CLIA Kit for Human Interstitial collagenase

Cat.:

U0097b

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Interstitial collagenase

Cat.:

U0097r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Interstitial collagenase

Cat.:

U0097h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Interstitial collagenase

Cat.:

U0097p

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Interstitial collagenase

Cat.:

P0097Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Interstitial collagenase

Cat.:

P0097Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Interstitial collagenase

Protein for Human Interstitial collagenase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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Citations

[1].

"The protective effect of xanthan gum on interleukin-1β induced rabbit chondrocytes"

G Han, H Shao, X Zhu, et al.

From:Carbohydrate Polymers

References

1.

"Cloning and characterization of human tumor cell interstitial collagenase."
Templeton N.S. , Brown P.D. , Levy A.T. , Margulies I.M.K. , Liotta L.A. , Stetler-Stevenson W.G.
Cancer Res.50:5431-5437(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
2.

"Comparison of human stromelysin and collagenase by cloning and sequence analysis."
Whitham S.E. , Murphy G. , Angel P. , Rahmsdorf H.J. , Smith B. , Lyons A. , Harris T.J.R. , Reynolds J.J. , Herrlich P. , Docherty A.J.P.
Biochem. J.240:913-916(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein."
Goldberg G.I. , Wilhelm S.M. , Kronberger A. , Bauer E.A. , Grant G.A. , Eisen A.Z.
J. Biol. Chem.261:6600-6605(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Three matrix metalloproteinases on 81kb of P1 insert."
Lin D. , Duncan M. , Allen E. , Araujo R. , Aparicio A. , Chai A. , Chung E. , Davis K. , Federspiel N. , Hyman R. , Kalman S. , Komp C. , Kurdi O. , Lashkari D. , Lew H. , Namath A. , Oefner P. , Roberts D. , more...
Submitted (1996-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.

NIEHS SNPs program
Submitted (2004-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-191; GLN-405 AND THR-406
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Ovary.
8.

"12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region."
Angel P. , Baumann I. , Stein B. , Delius H. , Rahmsdorf H.J. , Herrlich P.
Mol. Cell. Biol.7:2256-2266(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-35
9.

"Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA."
Brinckerhoff C.E. , Ruby P.L. , Austin S.D. , Fini M.E. , White H.D.
J. Clin. Invest.79:542-546(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-70
tissue: Synovial cell.
10.

"Fragments of human fibroblast collagenase. Purification and characterization."
Clark I.M. , Cawston T.E.
Biochem. J.263:201-206(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 100-112 AND 270-287
tissue: Fibroblast.
11.

"Human fibroblast collagenase contains an amino acid sequence homologous to the zinc-binding site of Serratia protease."
McKerrow J.H.
J. Biol. Chem.262:5943-5943(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SIMILARITY TO THERMOLYSIN TYPE PROTEASES
12.

"Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity."
Desrochers P.E. , Jeffrey J.J. , Weiss S.J.
J. Clin. Invest.87:2258-2265(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
13.

"N-glycan structures of matrix metalloproteinase-1 derived from human fibroblasts and from HT-1080 fibrosarcoma cells."
Saarinen J. , Welgus H.G. , Flizar C.A. , Kalkkinen N. , Helin J.
Eur. J. Biochem.259:829-840(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-120
14.

"Interaction of HIV Tat and matrix metalloproteinase in HIV neuropathogenesis: a new host defense mechanism."
Rumbaugh J. , Turchan-Cholewo J. , Galey D. , St Hillaire C. , Anderson C. , Conant K. , Nath A.
FASEB J.20:1736-1738(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 TAT
15.

"A secreted tyrosine kinase acts in the extracellular environment."
Bordoli M.R. , Yum J. , Breitkopf S.B. , Thon J.N. , Italiano J.E. Jr. , Xiao J. , Worby C. , Wong S.K. , Lin G. , Edenius M. , Keller T.L. , Asara J.M. , Dixon J.E. , Yeo C.Y. , Whitman M.
Cell158:1033-1044(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-360;MUTAGENESIS OF TYR-360
16.

"Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor."
Borkakoti N. , Winkler F.K. , Williams D.H. , D'Arcy A. , Broadhurst M.J. , Brown P.A. , Johnson W.H. , Murray E.J.
Nat. Struct. Biol.1:106-110(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 100-269
17.

"Crystal structures of recombinant 19-kDa human fibroblast collagenase complexed to itself."
Lovejoy B. , Hassell A.M. , Luther M.A. , Weigl D. , Jordan S.R.
Biochemistry33:8207-8217(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 102-269
18.

"Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor."
Lovejoy B. , Cleasby A. , Hassell A.M. , Longley K. , Luther M.A. , Weigl D. , McGeehan G. , McElroy A.B. , Drewry D. , Lambert M.H. , Jordan S.R.
Science263:375-377(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 102-269
19.

"1.56-A structure of mature truncated human fibroblast collagenase."
Spurlino J.C. , Smallwood A.M. , Carlton D.D. , Banks T.M. , Vavra K.J. , Johnson J.S. , Cook E.R. , Falvo J. , Wahl R.C. , Pulvino T.A. , Et A.L.
Proteins19:98-109(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.56 ANGSTROMS) OF 101-269
20.

"High-resolution solution structure of the inhibitor-free catalytic fragment of human fibroblast collagenase determined by multidimensional NMR."
Moy F.J. , Chanda P.K. , Cosmi S. , Pisano M.R. , Urbano C. , Wilhelm J. , Powers R.
Biochemistry37:1495-1504(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 101-269

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