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Index > Protein center > Mta1(Gene name) > Mouse
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  • Mta1 (Gene name),
  • Metastasis-associated protein MTA1 (Protein name ),  MTA1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mta1;
    Protein name:
    Metastasis-associated protein MTA1;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD). Interacts with HDAC1 and ITGB3BP/CENPR.
    Function:
    May be involved in the regulation of gene expression by covalent modification of histone proteins.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    715
    Sequence:
    50:
    MAANMYRVGD | YVYFENSSSN | PYLIRRIEEL | NKTANGNVEA | KVVCFYRRRD | 
    100:
    ISSSLIALAD | KHATLSVCYR | AGPGADTGEE | GEVEEEVENP | EMVDLPEKLK | 
    150:
    HQLRHRELFL | SRQLESLPAT | HIRGKCSVTL | LNETESLKSY | LEREDFFFYS | 
    200:
    LVYDPQQKTL | LADKGEIRVG | NRYQADITDL | LKEGEEDGRD | QSKLETKVWE | 
    250:
    AHNPLVDKQI | DQFLVVARSV | GTFARALDCS | SSVRQPSLHM | SAAAASRDIT | 
    300:
    LFHAMDTLHK | NIYDISKAIS | ALVPQGGPVL | CRDEMEEWSA | SEANLFEEAL | 
    350:
    EKYGKDFTDI | QQDFLPWKSL | TSIIEYYYMW | KTTDRYVQQK | RLKAAEAESK | 
    400:
    LKQVYIPNYN | KPNPNQISAS | SVKATVVNGT | GTPGQSPGAG | RACESCYTTQ | 
    450:
    SYQWYSWGPP | NMQCRLCASC | WTYWKKYGGL | KMPTRLDGER | PGPNRNNMSP | 
    500:
    HGIPARSSGS | PKFAMKTRQA | FYLHTTKLTR | IARRLCREIL | RPWHAARHPY | 
    550:
    MPINSAAIKA | ECTARLPEAS | QSPLVLKQVV | RKPLEAVLRY | LETHPRPPKP | 
    600:
    DPVKSSSSVL | SSLTPAKSAP | VINNGSPTIL | GKRSYEQHNG | VDGNMKKRLL | 
    650:
    MPSRGLANHG | QTRHMGPSRN | LLLNGKSYPT | KVRLIRGGSL | PPVKRRRMNW | 
    700:
    IDAPDDVFYM | ATEETRKIRK | LLSSSETKRA | ARRPYKPIAL | RQSQALPLRP | 
    715:
    PPPAPVNDEP | IVIED
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Metastasis-associated protein MTA1
    ELISA Kit for Mouse Metastasis-associated protein MTA1
    ELISA Kit for Mouse Metastasis-associated protein MTA1
    CLIA Kit for Mouse Metastasis-associated protein MTA1
    CLIA Kit for Mouse Metastasis-associated protein MTA1
    CLIA Kit for Mouse Metastasis-associated protein MTA1
    Polyclonal Antibody for Mouse Metastasis-associated protein MTA1
    Polyclonal Antibody for Mouse Metastasis-associated protein MTA1
    Polyclonal Antibody for Mouse Metastasis-associated protein MTA1
    Monoclonal Antibody for Mouse Metastasis-associated protein MTA1
    Monoclonal Antibody for Mouse Metastasis-associated protein MTA1
    Monoclonal Antibody for Mouse Metastasis-associated protein MTA1
    Protein for Mouse Metastasis-associated protein MTA1
    Protein for Mouse Metastasis-associated protein MTA1
    Protein for Mouse Metastasis-associated protein MTA1

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    References
    1. 1.
      "The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression."
      Zhou J. , Ashouian N. , Delepine M. , Matsuda F. , Chevillard C. , Riblet R. , Schildkraut C.L. , Birshtein B.K.
      Proc. Natl. Acad. Sci. U.S.A.99:13693-13698(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      strain: BALB/c.
    2. 2.
      "Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3."
      Simpson A. , Uitto J. , Rodeck U. , Mahoney M.G.
      Gene273:29-39(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
      strain: 129/Sv.
    3. 3.
      Takiguchi S.
      Submitted (2000-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/SvJ.
      tissue: Liver.
    4. 4.
      "Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase."
      Mishra S.K. , Yang Z. , Mazumdar A. , Talukder A.H. , Larose L. , Kumar R.
      Oncogene23:4422-4429(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY CSNK1G2/CK1;MUTAGENESIS OF SER-322;INTERACTION WITH CSNK1G2;SUBCELLULAR LOCATION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-564;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SIX3
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TP53
    11. 11.
      "E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1."
      Li D.Q. , Ohshiro K. , Reddy S.D. , Pakala S.B. , Lee M.H. , Zhang Y. , Rayala S.K. , Kumar R.
      Proc. Natl. Acad. Sci. U.S.A.106:17493-17498(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    12. 12.
      "Metastasis-associated protein 1 and its short form variant stimulates Wnt1 transcription through promoting its derepression from Six3 corepressor."
      Kumar R. , Balasenthil S. , Manavathi B. , Rayala S.K. , Pakala S.B.
      Cancer Res.70:6649-6658(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    13. 13.
      "Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway."
      Li D.Q. , Pakala S.B. , Reddy S.D. , Ohshiro K. , Peng S.H. , Lian Y. , Fu S.W. , Kumar R.
      J. Biol. Chem.285:10044-10052(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    14. 14.
      "Regulation of NF-kappaB circuitry by a component of the nucleosome remodeling and deacetylase complex controls inflammatory response homeostasis."
      Pakala S.B. , Bui-Nguyen T.M. , Reddy S.D. , Li D.Q. , Peng S. , Rayala S.K. , Behringer R.R. , Kumar R.
      J. Biol. Chem.285:23590-23597(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HDAC2;INDUCTION
    15. 15.
      "SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function."
      Cong L. , Pakala S.B. , Ohshiro K. , Li D.Q. , Kumar R.
      J. Biol. Chem.286:43793-43808(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    16. 16.
      "Metastasis-associated protein 1 is an integral component of the circadian molecular machinery."
      Li D.Q. , Pakala S.B. , Reddy S.D. , Peng S. , Balasenthil S. , Deng C.X. , Lee C.C. , Rea M.A. , Kumar R.
      Nat. Commun.4:2545-2545(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;INTERACTION WITH CLOCK AND ARNTL
    17. 17.
      "The subcellular distribution and function of MTA1 in cancer differentiation."
      Liu J. , Xu D. , Wang H. , Zhang Y. , Chang Y. , Zhang J. , Wang J. , Li C. , Liu H. , Zhao M. , Lin C. , Zhan Q. , Huang C. , Qian H.
      Oncotarget5:5153-5164(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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