Gene name:
Nuak2 (Omphk2) ;
Protein name:
NUAK family SNF1-like kinase 2 ;
Alternative:
Omphalocele kinase 2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
Subcellular Location:
N/A
Protein Attributes:
50:
MESVALLQRP | SQAPSASALA | SESARPLADG | LIKSPKPLMK | KQAVKRHHHK |
100:
HNLRHRYEFL | ETLGKGTYGK | VKKARESSGR | LVAIKSIRKD | KIKDEQDLLH |
150:
IRREIEIMSS | LNHPHIIAIH | EVGRSRLVTV | FENSSKIVIV | MEYASRGDLY |
200:
DYISERPRLS | ERDARHFFRQ | IVSALHYCHQ | NGIVHRDLKL | ENILLDANGN |
250:
IKIADFGLSN | LYHKGKFLQT | FCGSPLYASP | EIVNGKPYVG | PEVDSWSLGV |
300:
LLYILVHGTM | PFDGQDHKTL | VKQISNGAYR | EPPKPSDACG | LIRWLLMVNP |
350:
TRRATLEDVA | SHWWVNWGYT | TGVGEQEALR | EGGHPSGDFG | RASMADWLRR |
400:
SSRPLLENGA | KVCSFFKQHV | PGGGSTVPGL | ERQHSLKKSR | KENDMAQNLQ |
450:
GDPAEDTSSR | PGKSSLKLPK | GILKKKSSTS | SGEVQEDPQE | LRPVPDTPGQ |
500:
PVPAVSLLPR | KGILKKSRQR | ESGYYSSPEP | SESGELLDAS | DVFVSGDPVE |
550:
QKSPQASGLL | LHRKGILKLN | GKFSRTALEG | TTPSTFGSLD | QLASSHPAAR |
600:
PSRPSGAVSE | DSILSSESFD | QLDLPERLPE | TPLRGCVSVD | NLRGLEQPPS |
639:
EGLKRWWQES | LGDSCFSLTD | CQEVTAAYRQ | ALGICSKLS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse NUAK family SNF1-like kinase 2
ELISA Kit for Mouse NUAK family SNF1-like kinase 2
ELISA Kit for Mouse NUAK family SNF1-like kinase 2
CLIA Kit for Mouse NUAK family SNF1-like kinase 2
CLIA Kit for Mouse NUAK family SNF1-like kinase 2
CLIA Kit for Mouse NUAK family SNF1-like kinase 2
Polyclonal Antibody for Mouse NUAK family SNF1-like kinase 2
Polyclonal Antibody for Mouse NUAK family SNF1-like kinase 2
Polyclonal Antibody for Mouse NUAK family SNF1-like kinase 2
Monoclonal Antibody for Mouse NUAK family SNF1-like kinase 2
Monoclonal Antibody for Mouse NUAK family SNF1-like kinase 2
Monoclonal Antibody for Mouse NUAK family SNF1-like kinase 2
Protein for Mouse NUAK family SNF1-like kinase 2
Protein for Mouse NUAK family SNF1-like kinase 2
Protein for Mouse NUAK family SNF1-like kinase 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6J .
tissue :
Cecum .
tissue :
Diencephalon .
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6 .
strain :
Czech II .
tissue :
Brain .
tissue :
Mammary gland .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-588;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .