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Index > Protein center > HCRTR2(Gene name) > Human
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  • HCRTR2 (Gene name),
  • Orexin receptor type 2 (Protein name ),  OX2R_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HCRTR2;
    Protein name:
    Orexin receptor type 2(Ox-2-R;Ox2-R;Ox2R);
    Alternative:
    Hypocretin receptor type 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    444
    Sequence:
    50:
    MSGTKLEDSP | PCRNWSSASE | LNETQEPFLN | PTDYDDEEFL | RYLWREYLHP | 
    100:
    KEYEWVLIAG | YIIVFVVALI | GNVLVCVAVW | KNHHMRTVTN | YFIVNLSLAD | 
    150:
    VLVTITCLPA | TLVVDITETW | FFGQSLCKVI | PYLQTVSVSV | SVLTLSCIAL | 
    200:
    DRWYAICHPL | MFKSTAKRAR | NSIVIIWIVS | CIIMIPQAIV | MECSTVFPGL | 
    250:
    ANKTTLFTVC | DERWGGEIYP | KMYHICFFLV | TYMAPLCLMV | LAYLQIFRKL | 
    300:
    WCRQIPGTSS | VVQRKWKPLQ | PVSQPRGPGQ | PTKSRMSAVA | AEIKQIRARR | 
    350:
    KTARMLMIVL | LVFAICYLPI | SILNVLKRVF | GMFAHTEDRE | TVYAWFTFSH | 
    400:
    WLVYANSAAN | PIIYNFLSGK | FREEFKAAFS | CCCLGVHHRQ | EDRLTRGRTS | 
    444:
    TESRKSLTTQ | ISNFDNISKL | SEQVVLTSIS | TLPAANGAGP | LQNW
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    UniGene:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ox-2-R
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    E15164h
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    ELISA Kit for Human Ox-2-R
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    E15164m
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    ELISA Kit for Human Ox-2-R
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    E15164r
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    ELISA Kit for Human Ox-2-R
    Cat.:
    E15164d
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    96T
    ELISA Kit for Human Ox-2-R
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    E15164p
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    Packing:
    96T
    CLIA Kit for Human Ox-2-R
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    U15164d
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    Packing:
    96T
    CLIA Kit for Human Ox-2-R
    Cat.:
    U15164r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Ox-2-R
    Cat.:
    U15164h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Ox-2-R
    Cat.:
    U15164m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Ox-2-R
    Cat.:
    U15164p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Ox-2-R
    Polyclonal Antibody for Human Ox-2-R
    Cat.:
    P15164Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Ox-2-R
    Cat.:
    P15164Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Ox-2-R
    Polyclonal Antibody for Human Ox-2-R
    Cat.:
    P15164Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Ox-2-R
    Monoclonal Antibody for Human Ox-2-R
    Monoclonal Antibody for Human Ox-2-R
    Monoclonal Antibody for Human Ox-2-R
    Monoclonal Antibody for Human Ox-2-R
    Protein for Human Ox-2-R
    Protein for Human Ox-2-R
    Protein for Human Ox-2-R
    Protein for Human Ox-2-R
    Protein for Human Ox-2-R

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    References
    1. 1.
      "Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior."
      Sakurai T. , Amemiya A. , Ishii M. , Matsuzaki I. , Chemelli R.M. , Tanaka H. , Williams S.C. , Richardson J.A. , Kozlowski G.P. , Wilson S. , Arch J.R.S. , Buckingham R.E. , Haynes A.C. , Carr S.A. , Annan R.S. , McNulty D.E. , Liu W.-S. , Terrett J.A. , more...
      Cell92:573-585(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-308
    2. 2.
      "Polymorphisms in hypocretin/orexin pathway genes and narcolepsy."
      Olafsdottir B.R. , Rye D.B. , Scammell T.E. , Matheson J.K. , Stefansson K. , Gulcher J.R.
      Neurology57:1896-1899(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-10; THR-11; VAL-293 AND VAL-308
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Hypocretin/orexin, sleep and narcolepsy."
      Hungs M. , Mignot E.
      Bioessays23:397-408(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    6. 6.
      "To eat or to sleep? Orexin in the regulation of feeding and wakefulness."
      Willie J.T. , Chemelli R.M. , Sinton C.M. , Yanagisawa M.
      Annu. Rev. Neurosci.24:429-458(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
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