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Index > Protein center > Phb(Gene name) > Mouse
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  • Phb (Gene name),
  • Prohibitin (Protein name ),  PHB_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Phb;
    Protein name:
    Prohibitin;
    Alternative:
    B-cell receptor-associated protein 32(BAP 32);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with PHB2.
    Function:
    Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
    Subcellular Location:
    Mitochondrion inner membrane
    Protein Attributes:
    Sequence length:
    272
    Sequence:
    50:
    MAAKVFESIG | KFGLALAVAG | GVVNSALYNV | DAGHRAVIFD | RFRGVQDIVV | 
    100:
    GEGTHFLIPW | VQKPIIFDCR | SRPRNVPVIT | GSKDLQNVNI | TLRILFRPVA | 
    150:
    SQLPRIYTSI | GEDYDERVLP | SITTEILKSV | VARFDAGELI | TQRELVSRQV | 
    200:
    SDDLTERAAT | FGLILDDVSL | THLTFGKEFT | EAVEAKQVAQ | QEAERARFVV | 
    250:
    EKAEQQKKAA | IISAEGDSKA | AELIANSLAT | AGDGLIELRK | LEAAEDIAYQ | 
    272:
    LSRSRNITYL | PAGQSVLLQL | PQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Prohibitin
    ELISA Kit for Mouse Prohibitin
    ELISA Kit for Mouse Prohibitin
    ELISA Kit for Mouse Prohibitin
    ELISA Kit for Mouse Prohibitin
    CLIA Kit for Mouse Prohibitin
    CLIA Kit for Mouse Prohibitin
    CLIA Kit for Mouse Prohibitin
    CLIA Kit for Mouse Prohibitin
    CLIA Kit for Mouse Prohibitin
    Polyclonal Antibody for Mouse Prohibitin
    Polyclonal Antibody for Mouse Prohibitin
    Polyclonal Antibody for Mouse Prohibitin
    Polyclonal Antibody for Mouse Prohibitin
    Polyclonal Antibody for Mouse Prohibitin
    Monoclonal Antibody for Mouse Prohibitin
    Monoclonal Antibody for Mouse Prohibitin
    Monoclonal Antibody for Mouse Prohibitin
    Monoclonal Antibody for Mouse Prohibitin
    Monoclonal Antibody for Mouse Prohibitin
    Protein for Mouse Prohibitin
    Protein for Mouse Prohibitin
    Protein for Mouse Prohibitin
    Protein for Mouse Prohibitin
    Protein for Mouse Prohibitin

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    Precision
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    Linearity
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    References
    1. 1.
      "The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein."
      Terashima M. , Kim K.-M. , Adachi T. , Nielsen P.J. , Reth M. , Koehler G. , Lamers M.C.
      EMBO J.13:3782-3792(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      strain: BALB/c.
      tissue: Lymphoid tissue.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: DBA/2.
      tissue: Bone marrow.
      tissue: Heart.
      tissue: Kidney.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Eye.
    5. 5.
      Lubec G. , Klug S.
      Submitted (2007-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 12-34; 94-105; 158-177; 220-239 AND 241-253;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Hippocampus.
    6. 6.
      "Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence."
      Coates P.J. , Nenutil R. , McGregor A. , Picksley S.M. , Crouch D.H. , Hall P.A. , Wright E.G.
      Exp. Cell Res.265:262-273(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PHB2;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE
    7. 7.
      "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
      J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-249;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    8. 8.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-202;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
      tissue: Liver.
    9. 9.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-128; LYS-186 AND LYS-202;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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