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Index > Protein center > Plvap(Gene name) > Rat
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  • Plvap (Gene name),
  • Plasmalemma vesicle-associated protein (Protein name ),  PLVAP_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Plvap(Pv1);
    Protein name:
    Plasmalemma vesicle-associated protein;
    Alternative:
    gp68;Plasmalemma vesicle protein 1(PV-1);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein Membrane caveola Single-pass type II membrane protein Cytoplasm perinuclear region Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region.
    Protein Attributes:
    Sequence length:
    438
    Sequence:
    50:
    MGLSMDRSPY | SRTGDRDRGC | WYYLRYFFLF | VSLIQFLIIL | GLVLFMIYGN | 
    100:
    VHATTESSLR | ATEIRADNLY | SQVVGLSAAQ | ANLSKQLNIS | TLVKDTVMQQ | 
    150:
    LLTTRREVER | INASFRQCQG | DLITYINYNR | FIAAIILSEK | QCQEQLKEGN | 
    200:
    KTCEALLFKL | GEKVKTLEME | VVKEKAVCSK | DKDSLLAGKR | QAEMQQEACG | 
    250:
    KAREQQKQDQ | QVTEEQLRKV | QSLCLPLDQE | KFQADVLNVW | RDSLVYRSLD | 
    300:
    NIGYHYSLMP | EFSSLRRTCE | SLPGIMTTKV | EELARGLRAG | IERVTRENGE | 
    350:
    LRRQKLELER | AIQGEREART | RAGTEAQARE | TQLRTECARQ | TQLALEEKAA | 
    400:
    LRTQRDDLER | QLEARKRELE | QLRTEVDVRI | SALDTCVKAK | SLPAIQPRLP | 
    438:
    GPPPNPPPID | PASLEEFKKR | ILESQRPPLV | NPAVPPSG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Plasmalemma vesicle-associated protein
    ELISA Kit for Rat Plasmalemma vesicle-associated protein
    ELISA Kit for Rat Plasmalemma vesicle-associated protein
    CLIA Kit for Rat Plasmalemma vesicle-associated protein
    CLIA Kit for Rat Plasmalemma vesicle-associated protein
    CLIA Kit for Rat Plasmalemma vesicle-associated protein
    Polyclonal Antibody for Rat Plasmalemma vesicle-associated protein
    Polyclonal Antibody for Rat Plasmalemma vesicle-associated protein
    Polyclonal Antibody for Rat Plasmalemma vesicle-associated protein
    Monoclonal Antibody for Rat Plasmalemma vesicle-associated protein
    Monoclonal Antibody for Rat Plasmalemma vesicle-associated protein
    Monoclonal Antibody for Rat Plasmalemma vesicle-associated protein
    Protein for Rat Plasmalemma vesicle-associated protein
    Protein for Rat Plasmalemma vesicle-associated protein
    Protein for Rat Plasmalemma vesicle-associated protein

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    Linearity
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    References
    1. 1.
      "Isolation, cloning, and localization of rat PV-1, a novel endothelial caveolar protein."
      Stan R.-V. , Ghitescu L. , Jacobson B.S. , Palade G.E.
      J. Cell Biol.145:1189-1198(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1-16; 232-241 AND 248-264;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Lung endothelial cell.
    2. 2.
      "PV-1 is a component of the fenestral and stomatal diaphragms in fenestrated endothelia."
      Stan R.-V. , Kubitza M. , Palade G.E.
      Proc. Natl. Acad. Sci. U.S.A.96:13203-13207(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Lung endothelial cell.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    4. 4.
      "Distribution and characterization of plasmalemma vesicle protein-1 in rat endocrine glands."
      Hnasko R. , McFarland M. , Ben-Jonathan N.
      J. Endocrinol.175:649-661(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Multiple PV1 dimers reside in the same stomatal or fenestral diaphragm."
      Stan R.-V.
      Am. J. Physiol.286:H1347-H1353(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    6. 6.
      "Developmental regulation of PV-1 in rat lung: association with the nuclear envelope and limited colocalization with Cav-1."
      Hnasko R. , Ben-Jonathan N.
      Am. J. Physiol.288:L275-L284(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY
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