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Index > Protein center > PRLHR(Gene name) > Human
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  • PRLHR (Gene name),
  • Prolactin-releasing peptide receptor (Protein name ),  PRLHR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PRLHR(GPR10;GR3);
    Protein name:
    Prolactin-releasing peptide receptor(PrRP receptor;PrRPR);
    Alternative:
    hGR3;G-protein coupled receptor 10;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1.
    Function:
    Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    370
    Sequence:
    50:
    MASSTTRGPR | VSDLFSGLPP | AVTTPANQSA | EASAGNGSVA | GADAPAVTPF | 
    100:
    QSLQLVHQLK | GLIVLLYSVV | VVVGLVGNCL | LVLVIARVRR | LHNVTNFLIG | 
    150:
    NLALSDVLMC | TACVPLTLAY | AFEPRGWVFG | GGLCHLVFFL | QPVTVYVSVF | 
    200:
    TLTTIAVDRY | VVLVHPLRRR | ISLRLSAYAV | LAIWALSAVL | ALPAAVHTYH | 
    250:
    VELKPHDVRL | CEEFWGSQER | QRQLYAWGLL | LVTYLLPLLV | ILLSYVRVSV | 
    300:
    KLRNRVVPGC | VTQSQADWDR | ARRRRTFCLL | VVIVVVFAVC | WLPLHVFNLL | 
    350:
    RDLDPHAIDP | YAFGLVQLLC | HWLAMSSACY | NPFIYAWLHD | SFREELRKLL | 
    370:
    VAWPRKIAPH | GQNMTVSVVI | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    Pfam:
    MIM:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human PrRP receptor
    ELISA Kit for Human PrRP receptor
    ELISA Kit for Human PrRP receptor
    ELISA Kit for Human PrRP receptor
    CLIA Kit for Human PrRP receptor
    CLIA Kit for Human PrRP receptor
    CLIA Kit for Human PrRP receptor
    CLIA Kit for Human PrRP receptor
    Polyclonal Antibody for Human PrRP receptor
    Polyclonal Antibody for Human PrRP receptor
    Polyclonal Antibody for Human PrRP receptor
    Polyclonal Antibody for Human PrRP receptor
    Monoclonal Antibody for Human PrRP receptor
    Monoclonal Antibody for Human PrRP receptor
    Monoclonal Antibody for Human PrRP receptor
    Monoclonal Antibody for Human PrRP receptor
    Protein for Human PrRP receptor
    Protein for Human PrRP receptor
    Protein for Human PrRP receptor
    Protein for Human PrRP receptor

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors."
      Marchese A. , Heiber M. , Nguyen T. , Heng H.H.Q. , Saldivia V.R. , Cheng R. , Murphy P.M. , Tsui L.-C. , Shi X. , Gregor P. , George S.R. , O'Dowd B.F. , Docherty J.M.
      Genomics29:335-344(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-283
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-283
    3. 3.
      "Transcriptional regulation of the human PRL-releasing peptide (PrRP) receptor gene by a dopamine 2 receptor agonist: cloning and characterization of the human PrRP receptor gene and its promoter region."
      Ozawa A. , Yamada M. , Satoh T. , Monden T. , Hashimoto K. , Kohga H. , Hashiba Y. , Sasaki T. , Mori M.
      Mol. Endocrinol.16:785-798(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY;INDUCTION;VARIANT VAL-283
    4. 4.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-283
    6. 6.
      "Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor."
      Fujii R. , Fukusumi S. , Hosoya M. , Kawamata Y. , Habata Y. , Hinuma S. , Sekiguchi M. , Kitada C. , Kurokawa T. , Nishimura O. , Onda H. , Sumino Y. , Fujino M.
      Regul. Pept.83:1-10(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering."
      Lin S.H.S. , Arai A.C. , Wang Z. , Nothacker H.-P. , Civelli O.
      Mol. Pharmacol.60:916-923(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GRIP1; GRIP2 AND PICK1;MUTAGENESIS OF THR-365; VAL-366; SER-367; VAL-368; VAL-369 AND ILE-370
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