Abca4 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comAbca4 Polyclonal Antibody for Mouse(Mus musculus)

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Abca4 (Gene name),

Retinal-specific ATP-binding cassette transporter (Protein name ), ABCA4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Abca4(Abcr);

Protein name:

Retinal-specific ATP-binding cassette transporter;

Alternative:

RIM ABC transporter(RIM protein;RmP);ATP-binding cassette sub-family A member 4;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.

Subcellular Location:

Membrane Multi-pass membrane protein Localized to outer segment disk edges of rods and cones, with around one million copies/photoreceptor.

Protein Attributes:

Sequence length:

2310

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AEDKHTRSPQ |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O35600

KEGG:

mmu:11304

Pfam:

PF00005

SMR:

O35600

UniGene:

Mm.3918

Uniprot:

O35600

FOR

ELISA Kit for Mouse Retinal-specific ATP-binding cassette transporter

Cat.:

E10399h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Mouse Retinal-specific ATP-binding cassette transporter

Cat.:

E10399m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse Retinal-specific ATP-binding cassette transporter

Cat.:

U10399h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Retinal-specific ATP-binding cassette transporter

Cat.:

U10399m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Retinal-specific ATP-binding cassette transporter

Cat.:

P10399Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Retinal-specific ATP-binding cassette transporter

Cat.:

P10399Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Retinal-specific ATP-binding cassette transporter

Protein for Mouse Retinal-specific ATP-binding cassette transporter

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Azarian S.M. , Travis G.H.
Submitted (1998-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Eye.
3.

"Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice."
Weng J. , Mata N.L. , Azarian S.M. , Tzekov R.T. , Birch D.G. , Travis G.H.
Cell98:13-23(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE

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