Gene name:
CYP26B1 (CYP26A2;P450RAI2) ;
Protein name:
Cytochrome P450 26B1 ;
Alternative:
Cytochrome P450 retinoic acid-inactivating 2 (Cytochrome P450RAI-2) ;Cytochrome P450 26A2 ;Retinoic acid-metabolizing cytochrome ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Plays a key role in retinoic acid metabolism. Involved in the specific inactivation of all-trans-retinoic acid (RA). Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA.
Subcellular Location:
Endoplasmic reticulum membrane
Peripheral membrane protein
Microsome membrane
Peripheral membrane protein
Protein Attributes:
50:
MLFEGLDLVS | ALATLAACLV | SVTLLLAVSQ | QLWQLRWAAT | RDKSCKLPIP |
100:
KGSMGFPLIG | ETGHWLLQGS | GFQSSRREKY | GNVFKTHLLG | RPLIRVTGAE |
150:
NVRKILMGEH | HLVSTEWPRS | TRMLLGPNTV | SNSIGDIHRN | KRKVFSKIFS |
200:
HEALESYLPK | IQLVIQDTLR | AWSSHPEAIN | VYQEAQKLTF | RMAIRVLLGF |
250:
SIPEEDLGHL | FEVYQQFVDN | VFSLPVDLPF | SGYRRGIQAR | QILQKGLEKA |
300:
IREKLQCTQG | KDYLDALDLL | IESSKEHGKE | MTMQELKDGT | LELIFAAYAT |
350:
TASASTSLIM | QLLKHPTVLE | KLRDELRAHG | ILHSGGCPCE | GTLRLDTLSG |
400:
LRYLDCVIKE | VMRLFTPISG | GYRTVLQTFE | LDGFQIPKGW | SVMYSIRDTH |
450:
DTAPVFKDVN | VFDPDRFSQA | RSEDKDGRFH | YLPFGGGVRT | CLGKHLAKLF |
500:
LKVLAVELAS | TSRFELATRT | FPRITLVPVL | HPVDGLSVKF | FGLDSNQNEI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rat
Human
Mouse
ELISA Kit for Human Cytochrome P450 26B1
ELISA Kit for Human Cytochrome P450 26B1
ELISA Kit for Human Cytochrome P450 26B1
ELISA Kit for Human Cytochrome P450 26B1
CLIA Kit for Human Cytochrome P450 26B1
CLIA Kit for Human Cytochrome P450 26B1
CLIA Kit for Human Cytochrome P450 26B1
CLIA Kit for Human Cytochrome P450 26B1
Polyclonal Antibody for Human Cytochrome P450 26B1
Polyclonal Antibody for Human Cytochrome P450 26B1
Polyclonal Antibody for Human Cytochrome P450 26B1
Polyclonal Antibody for Human Cytochrome P450 26B1
Monoclonal Antibody for Human Cytochrome P450 26B1
Monoclonal Antibody for Human Cytochrome P450 26B1
Monoclonal Antibody for Human Cytochrome P450 26B1
Monoclonal Antibody for Human Cytochrome P450 26B1
Protein for Human Cytochrome P450 26B1
Protein for Human Cytochrome P450 26B1
Protein for Human Cytochrome P450 26B1
Protein for Human Cytochrome P450 26B1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
tissue :
Retina .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANT SER-264
tissue :
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3);VARIANT SER-264
tissue :
Brain .
tissue :
Cerebellum .
tissue :
Hippocampus .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS MET-181; VAL-185; HIS-191; ASN-227; SER-264; LYS-380; GLY-420; CYS-473 AND ILE-479
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[
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.
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Am. J. Hum. Genet.89:595-606(2011)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;VARIANTS RHFCA PRO-146 AND LEU-363