Gene name:
AHSP (EDRF;ERAF) ;
Protein name:
Alpha-hemoglobin-stabilizing protein ;
Alternative:
Erythroid-associated factor ;Erythroid differentiation-related factor ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Monomer. Forms an heterodimer with free alpha-hemoglobin. Does not bind beta-hemoglobin nor alpha(2)beta(2) hemoglobin A.
Function:
Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MALLKANKDL | ISAGLKEFSV | LLNQQVFNDP | LVSEEDMVTV | VEDWMNFYIN |
100:
YYRQQVTGEP | QERDKALQEL | RQELNTLANP | FLAKYRDFLK | SHELPSHPPP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
ELISA Kit for Human Alpha-hemoglobin-stabilizing protein
ELISA Kit for Human Alpha-hemoglobin-stabilizing protein
ELISA Kit for Human Alpha-hemoglobin-stabilizing protein
CLIA Kit for Human Alpha-hemoglobin-stabilizing protein
CLIA Kit for Human Alpha-hemoglobin-stabilizing protein
CLIA Kit for Human Alpha-hemoglobin-stabilizing protein
Polyclonal Antibody for Human Alpha-hemoglobin-stabilizing protein
Polyclonal Antibody for Human Alpha-hemoglobin-stabilizing protein
Polyclonal Antibody for Human Alpha-hemoglobin-stabilizing protein
Monoclonal Antibody for Human Alpha-hemoglobin-stabilizing protein
Monoclonal Antibody for Human Alpha-hemoglobin-stabilizing protein
Monoclonal Antibody for Human Alpha-hemoglobin-stabilizing protein
Protein for Human Alpha-hemoglobin-stabilizing protein
Protein for Human Alpha-hemoglobin-stabilizing protein
Protein for Human Alpha-hemoglobin-stabilizing protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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tissue :
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cell119:629-640(2004)
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Cited for : X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) IN COMPLEX WITH HBA