Gene name:
PLAUR (MO3;UPAR) ;
Protein name:
Urokinase plasminogen activator surface receptor (U-PAR;uPAR) ;
Alternative:
Monocyte activation antigen Mo3 ;
CD:
CD87 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2.
Function:
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Subcellular Location:
Isoform 2
Secreted
Protein Attributes:
50:
MGHPPLLPLL | LLLHTCVPAS | WGLRCMQCKT | NGDCRVEECA | LGQDLCRTTI |
100:
VRLWEEGEEL | ELVEKSCTHS | EKTNRTLSYR | TGLKITSLTE | VVCGLDLCNQ |
150:
GNSGRAVTYS | RSRYLECISC | GSSDMSCERG | RHQSLQCRSP | EEQCLDVVTH |
200:
WIQEGEEGRP | KDDRHLRGCG | YLPGCPGSNG | FHNNDTFHFL | KCCNTTKCNE |
250:
GPILELENLP | QNGRQCYSCK | GNSTHGCSSE | ETFLIDCRGP | MNQCLVATGT |
300:
HEPKNQSYMV | RGCATASMCQ | HAHLGDAFSM | NHIDVSCCTK | SGCNHPDLDV |
335:
QYRSGAAPQP | GPAHLSLTIT | LLMTARLWGG | TLLWT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Human U-PAR
ELISA Kit for Human U-PAR
ELISA Kit for Human U-PAR
ELISA Kit for Human U-PAR
Polyclonal Antibody for Human U-PAR
Polyclonal Antibody for Human U-PAR
Polyclonal Antibody for Human U-PAR
Polyclonal Antibody for Human U-PAR
Monoclonal Antibody for Human U-PAR
Monoclonal Antibody for Human U-PAR
Monoclonal Antibody for Human U-PAR
Monoclonal Antibody for Human U-PAR
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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PubMed ]
[
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Cited for : X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 23-297 IN COMPLEX WITH PLAU;GLYCOSYLATION AT ASN-74 AND ASN-194;DISULFIDE BONDS
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Cited for : X-RAY CRYSTALLOGRAPHY (2.39 ANGSTROMS) OF 23-305 OF MUTANT CYS-69 AND CYS-281 ALONE AND IN COMPLEX WITH PLAU;DISULFIDE BONDS;GLYCOSYLATION AT ASN-74 AND ASN-222