S100a13 ELISA Kit for Mouse(Mus musculus) | EIAab.comS100a13 ELISA Kit for Mouse(Mus musculus)

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S100a13 (Gene name),

Protein S100-A13 (Protein name ), S10AD_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

S100a13;

Protein name:

Protein S100-A13;

Alternative:

S100 calcium-binding protein A13;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer. Part of a copper-dependent multiprotein complex containing S100A13, FGF1 and SYT1. Interacts with FGF1 and SYT1.

Function:

Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine.

Subcellular Location:

Cytoplasm Secreted Secretion is mediated by exposure to stress and requires copper ions.

Protein Attributes:

Sequence length:

Sequence:

50:

98:

KDVGSLDEKM | KTLDVNQDSE | LRFSEYWRLI | GELAKEVRKE | KALGIRKK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P97352

KEGG:

mmu:20196

Pfam:

PF01023

UniGene:

Mm.6523

SMR:

P97352

STRING:

10090.ENSMUSP00000102961

Uniprot:

P97352

FOR

ELISA Kit for Mouse Protein S100-A13

CLIA Kit for Mouse Protein S100-A13

Polyclonal Antibody for Mouse Protein S100-A13

Monoclonal Antibody for Mouse Protein S100-A13

Protein for Mouse Protein S100-A13

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Characterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein family."
Wicki R. , Schaefer B.W. , Erne P. , Heizmann C.W.
Biochem. Biophys. Res. Commun.227:594-599(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Mammary tumor.
3.

"The intracellular translocation of the components of the fibroblast growth factor 1 release complex precedes their assembly prior to export."
Prudovsky I. , Bagala C. , Tarantini F. , Mandinova A. , Soldi R. , Bellum S. , Maciag T.
J. Cell Biol.158:201-208(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
4.

"S100A13 mediates the copper-dependent stress-induced release of IL-1alpha from both human U937 and murine NIH 3T3 cells."
Mandinova A. , Soldi R. , Graziani I. , Bagala C. , Bellum S. , Landriscina M. , Tarantini F. , Prudovsky I. , Maciag T.
J. Cell Sci.116:2687-2696(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
5.

"S100A13-lipid interactions-role in the non-classical release of the acidic fibroblast growth factor."
Kathir K.M. , Ibrahim K. , Rajalingam D. , Prudovsky I. , Yu C. , Kumar T.K.
Biochim. Biophys. Acta1768:3080-3089(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH LIPID VESICLES
6.

"Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress."
Landriscina M. , Bagala C. , Mandinova A. , Soldi R. , Micucci I. , Bellum S. , Prudovsky I. , Maciag T.
J. Biol. Chem.276:25549-25557(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SYT1 AND FGF1;COPPER BINDING;IDENTIFICATION IN A COPPER-DEPENDENT MULTIPROTEIN COMPLEX CONTAINING SYT1; FGF1 AND S100A13
7.

"Protein folding does not prevent the nonclassical export of FGF1 and S100A13."
Graziani I. , Doyle A. , Sterling S. , Kirov A. , Tarantini F. , Landriscina M. , Kumar T.K. , Neivandt D. , Prudovsky I.
Biochem. Biophys. Res. Commun.381:350-354(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
8.

"Three-dimensional solution structure of S100A13."
Vaithiyalingam S. , Kumar T.K.S. , Yu C.
Submitted (2009-02) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR;SUBUNIT

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