Gene name:
SERPINH1 (PIG14;CBP1;CBP2;HSP47;SERPINH2) ;
Protein name:
Serpin H1 ;
Alternative:
Arsenic-transactivated protein 3 (AsTP3) ;47 kDa heat shock protein ;Collagen-binding protein (Colligin) ;Cell proliferation-inducing gene 14 protein ;Rheumatoid arthritis-related antigen RA-A47 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
Subcellular Location:
Endoplasmic reticulum lumen
Protein Attributes:
50:
MRSLLLLSAF | CLLEAALAAE | VKKPAAAAAP | GTAEKLSPKA | ATLAERSAGL |
100:
AFSLYQAMAK | DQAVENILVS | PVVVASSLGL | VSLGGKATTA | SQAKAVLSAE |
150:
QLRDEEVHAG | LGELLRSLSN | STARNVTWKL | GSRLYGPSSV | SFADDFVRSS |
200:
KQHYNCEHSK | INFRDKRSAL | QSINEWAAQT | TDGKLPEVTK | DVERTDGALL |
250:
VNAMFFKPHW | DEKFHHKMVD | NRGFMVTRSY | TVGVMMMHRT | GLYNYYDDEK |
300:
EKLQIVEMPL | AHKLSSLIIL | MPHHVEPLER | LEKLLTKEQL | KIWMGKMQKK |
350:
AVAISLPKGV | VEVTHDLQKH | LAGLGLTEAI | DKNKADLSRM | SGKKDLYLAS |
400:
VFHATAFELD | TDGNPFDQDI | YGREELRSPK | LFYADHPFIF | LVRDTQSGSL |
418:
LFIGRLVRPK | GDKMRDEL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Chicken
Bovine
Rat
ELISA Kit for Human Serpin H1
ELISA Kit for Human Serpin H1
ELISA Kit for Human Serpin H1
ELISA Kit for Human Serpin H1
ELISA Kit for Human Serpin H1
CLIA Kit for Human Serpin H1
CLIA Kit for Human Serpin H1
CLIA Kit for Human Serpin H1
CLIA Kit for Human Serpin H1
CLIA Kit for Human Serpin H1
Polyclonal Antibody for Human Serpin H1
Polyclonal Antibody for Human Serpin H1
Polyclonal Antibody for Human Serpin H1
Polyclonal Antibody for Human Serpin H1
Polyclonal Antibody for Human Serpin H1
Monoclonal Antibody for Human Serpin H1
Monoclonal Antibody for Human Serpin H1
Monoclonal Antibody for Human Serpin H1
Monoclonal Antibody for Human Serpin H1
Monoclonal Antibody for Human Serpin H1
Protein for Human Serpin H1
Protein for Human Serpin H1
Protein for Human Serpin H1
Protein for Human Serpin H1
Protein for Human Serpin H1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Fibroblast .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Cartilage .
tissue :
Fibroblast .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
5.
"Identification of a human cell proliferation gene 14."
Kim J.W.
Submitted (2003-03) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N.
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Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
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more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
8.
Mural R.J.
,
Istrail S.
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Sutton G.G.
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Florea L.
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Halpern A.L.
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Mobarry C.M.
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Lippert R.
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Walenz B.
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Myers E.W.
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Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
tissue :
Ovary .
tissue :
Skin .
10.
"A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans."
Wang H.
,
Parry S.
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Macones G.
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Sammel M.D.
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Kuivaniemi H.
,
Tromp G.
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Argyropoulos G.
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Halder I.
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Shriver M.D.
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Romero R.
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Strauss J.F. III
Proc. Natl. Acad. Sci. U.S.A.103:13463-13467(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : POLYMORPHISM IN PROMOTER;INVOLVEMENT IN PPROM
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.
"Homozygosity for a missense mutation in SERPINH1, which encodes the collagen chaperone protein HSP47, results in severe recessive osteogenesis imperfecta."
Christiansen H.E.
,
Schwarze U.
,
Pyott S.M.
,
AlSwaid A.
,
Al Balwi M.
,
Alrasheed S.
,
Pepin M.G.
,
Weis M.A.
,
Eyre D.R.
,
Byers P.H.
Am. J. Hum. Genet.86:389-398(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT OI10 PRO-78