SHC2 ELISA Kit for Human(Homo sapiens) | EIAab.comSHC2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SHC2(Gene name) > Human

SHC2 (Gene name),

SHC-transforming protein 2 (Protein name ), SHC2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SHC2(SCK;SHCB);

Protein name:

SHC-transforming protein 2;

Alternative:

SHC-transforming protein B;Protein Sck;Src homology 2 domain-containing-transforming protein C2(SH2 domain protein C2);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2.

Function:

Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

582

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

582:

ISHLIDHHLQ | NGQPIVAAES | ELHLRGVVSR | EP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P98077

KEGG:

hsa:25759

Pfam:

PF00640

STRING:

9606.ENSP00000264554

UniGene:

Hs.30965

MIM:

605217

SMR:

P98077

Uniprot:

P98077

FOR

ELISA Kit for Human SHC-transforming protein 2

CLIA Kit for Human SHC-transforming protein 2

Polyclonal Antibody for Human SHC-transforming protein 2

Monoclonal Antibody for Human SHC-transforming protein 2

Protein for Human SHC-transforming protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling."
Nakamura T. , Muraoka S. , Sanokawa R. , Mori N.
J. Biol. Chem.273:6960-6967(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 45-582;INTERACTION WITH THE TRK RECEPTORS;TISSUE SPECIFICITY
3.

"A family of Shc related proteins with conserved PTB, CH1 and SH2 regions."
Pelicci G. , Dente L. , De Giuseppe A. , Verducci-Galletti B. , Giuli S. , Mele S. , Vetriani C. , Giorgio M. , Pandolfi P.P. , Cesareni G. , Pelicci P.-G.
Oncogene13:633-641(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 96-582
tissue: Fetal brain.
4.

"An alternative to SH2 domains for binding tyrosine-phosphorylated proteins."
Kavanaugh W.M. , Williams L.T.
Science266:1862-1865(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 114-541
5.

The European IMAGE consortium
Submitted (2000-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 191-582
6.

"ShcB and ShcC activation by the Trk family of receptor tyrosine kinases."
Liu H.Y. , Meakin S.O.
J. Biol. Chem.277:26046-26056(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;INTERACTION WITH THE TRK RECEPTORS
7.

"Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation."
Nanda N. , Bao M. , Lin H. , Clauser K. , Komuves L. , Quertermous T. , Conley P.B. , Phillips D.R. , Hart M.J.
J. Biol. Chem.280:24680-24689(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MEGF12
tissue: Platelet.

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