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Index > Protein center > Spc25(Gene name) > Mouse
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  • Spc25 (Gene name),
  • Kinetochore protein Spc25 (Protein name ),  SPC25_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Spc25(Spbc25);
    Protein name:
    Kinetochore protein Spc25;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the NDC80 complex, which consists of NDC80/HEC1, CDCA1, SPBC24 and SPBC25. The NDC80 complex is formed by two subcomplexes composed of NDC80/HEC1-CDCA1 and SPBC24-SPBC25. Each subcomplex is formed by parallel interactions through the coiled-coil domains of individual subunits. Formation of a tetrameric complex is mediated by interactions between the C-terminal regions of both subunits of the NDC80/HEC1-CDCA1 subcomplex and the N-terminal regions of both subunits of the SPBC24-SPBC25 complex. The tetrameric NDC80 complex has an elongated rod-like structure with globular domains at either end.
    Function:
    Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
    Subcellular Location:
    Nucleus Chromosome centromere kinetochore Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.
    Protein Attributes:
    Sequence length:
    226
    Sequence:
    50:
    MGEDELALLN | QSINEFGDKF | RNRLDDNHSQ | VLGLRDAFKD | SMKAFSEKMS | 
    100:
    LKLKEEERMT | EMILEYKNQL | CKQNKLIQEK | KENVLKMIAE | VKGKEQESEE | 
    150:
    LTAKIQELKE | EYARKRETIS | TANKANEERL | KGLQKSADLY | RDYLGLEIRK | 
    200:
    IHGNKLQFIF | TSIDPKNPES | PYMFSMSINE | AKEYEVYDSS | PHLECLAEFQ | 
    226:
    EKVRKTNNFS | AFLANIRKAF | IAKVHN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Kinetochore protein Spc25
    ELISA Kit for Mouse Kinetochore protein Spc25
    ELISA Kit for Mouse Kinetochore protein Spc25
    ELISA Kit for Mouse Kinetochore protein Spc25
    CLIA Kit for Mouse Kinetochore protein Spc25
    CLIA Kit for Mouse Kinetochore protein Spc25
    CLIA Kit for Mouse Kinetochore protein Spc25
    CLIA Kit for Mouse Kinetochore protein Spc25
    Polyclonal Antibody for Mouse Kinetochore protein Spc25
    Polyclonal Antibody for Mouse Kinetochore protein Spc25
    Polyclonal Antibody for Mouse Kinetochore protein Spc25
    Polyclonal Antibody for Mouse Kinetochore protein Spc25
    Monoclonal Antibody for Mouse Kinetochore protein Spc25
    Monoclonal Antibody for Mouse Kinetochore protein Spc25
    Monoclonal Antibody for Mouse Kinetochore protein Spc25
    Monoclonal Antibody for Mouse Kinetochore protein Spc25
    Protein for Mouse Kinetochore protein Spc25
    Protein for Mouse Kinetochore protein Spc25
    Protein for Mouse Kinetochore protein Spc25
    Protein for Mouse Kinetochore protein Spc25

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    Precision
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
      strain: C57BL/6J.
      tissue: Bone marrow.
      tissue: Embryo.
      tissue: Embryonic liver.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Retina.
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