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Index > Protein center > Stt3a(Gene name) > Mouse
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  • Stt3a (Gene name),
  • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Protein name ),  STT3A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Stt3a(Itm1);
    Protein name:
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A(Oligosaccharyl transferase subunit STT3A;STT3-A);
    Alternative:
    Integral membrane protein 1;B5;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the oligosaccharyltransferase (OST) complex. OST seems to exist in different forms which contain at least RPN1, RPN2, OST48, DAD1, OSTC, KRTCAP2 and either STT3A or STT3B. OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes.
    Function:
    Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    705
    Sequence:
    50:
    MTKLGFLRLS | YEKQDTLLKL | LILSMAAVLS | FSTRLFAVLR | FESVIHEFDP | 
    100:
    YFNYRTTRFL | AEEGFYKFHN | WFDDRAWYPL | GRIIGGTIYP | GLMITSAAIY | 
    150:
    HVLHFFHITI | DIRNVCVFLA | PLFSSFTTIV | TYHLTKELKD | AGAGLLAAAM | 
    200:
    IAVVPGYISR | SVAGSYDNEG | IAIFCMLLTY | YMWIKAVKTG | SIYWAAKCAL | 
    250:
    AYFYMVSSWG | GYVFLINLIP | LHVLVLMLTG | RFSHRIYVAY | CTVYCLGTIL | 
    300:
    SMQISFVGFQ | PVLSSEHMAA | FGVFGLCQIH | AFVDYLRSKL | NPQQFEVLFR | 
    350:
    SVISLVGFVL | LTVGALLMLT | GKISPWTGRF | YSLLDPSYAK | NNIPIIASVS | 
    400:
    EHQPTTWSSY | YFDLQLLVFM | FPVGLYYCFS | NLSDARIFII | MYGVTSMYFS | 
    450:
    AVMVRLMLVL | APVMCILSGI | GVSQVLSTYM | KNLDISRPDK | KSKKQQDSTY | 
    500:
    PIKNEVASGM | ILVMAFFLIT | YTFHSTWVTS | EAYSSPSIVL | SARGGDGSRI | 
    550:
    IFDDFREAYY | WLRHNTPEDA | KVMSWWDYGY | QITAMANRTI | LVDNNTWNNT | 
    600:
    HISRVGQAMA | STEEKAYEIM | RELDVSYVLV | IFGGLTGYSS | DDINKFLWMV | 
    650:
    RIGGSTETGR | HIKENDYYTP | TGEFRVDREG | SPVLLNCLMY | KMCYYRFGQV | 
    700:
    YTEAKRPPGF | DRVRNAEIGN | KDFELDVLEE | AYTTEHWLVR | IYKVKDLDNR | 
    705:
    GLSRT
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Oligosaccharyl transferase subunit STT3A
    ELISA Kit for Mouse Oligosaccharyl transferase subunit STT3A
    ELISA Kit for Mouse Oligosaccharyl transferase subunit STT3A
    CLIA Kit for Mouse Oligosaccharyl transferase subunit STT3A
    CLIA Kit for Mouse Oligosaccharyl transferase subunit STT3A
    CLIA Kit for Mouse Oligosaccharyl transferase subunit STT3A
    Polyclonal Antibody for Mouse Oligosaccharyl transferase subunit STT3A
    Polyclonal Antibody for Mouse Oligosaccharyl transferase subunit STT3A
    Polyclonal Antibody for Mouse Oligosaccharyl transferase subunit STT3A
    Monoclonal Antibody for Mouse Oligosaccharyl transferase subunit STT3A
    Monoclonal Antibody for Mouse Oligosaccharyl transferase subunit STT3A
    Monoclonal Antibody for Mouse Oligosaccharyl transferase subunit STT3A
    Protein for Mouse Oligosaccharyl transferase subunit STT3A
    Protein for Mouse Oligosaccharyl transferase subunit STT3A
    Protein for Mouse Oligosaccharyl transferase subunit STT3A

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning of a highly conserved mouse and human integral membrane protein (Itm1) and genetic mapping to mouse chromosome 9."
      Hong G. , Deleersnjider W. , Kozak C.A. , van Marck E. , Tylzanowski P. , Merregaert J.
      Genomics31:295-300(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Mandibular condyle.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary gland.
    3. 3.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 696-704;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    4. 4.
      "Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties."
      Kelleher D.J. , Karaoglu D. , Mandon E.C. , Gilmore R.
      Mol. Cell12:101-111(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex."
      Kim H. , von Heijne G. , Nilsson I.
      J. Biol. Chem.280:20261-20267(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TOPOLOGY
    6. 6.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-548
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