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Index > Protein center > STXBP3(Gene name) > Human
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  • STXBP3 (Gene name),
  • Syntaxin-binding protein 3 (Protein name ),  STXB3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    STXBP3;
    Protein name:
    Syntaxin-binding protein 3;
    Alternative:
    Protein unc-18 homolog 3(Unc18-3);Platelet Sec1 protein(PSP);Protein unc-18 homolog C(Unc-18C);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with DOC2B; the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion (By similarity). Interacts with STX4.
    Function:
    Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
    Subcellular Location:
    Cytoplasm cytosol Cell membrane In platelets, predominantly cytosolic. Low amounts membrane-associated.
    Protein Attributes:
    Sequence length:
    592
    Sequence:
    50:
    MAPPVAERGL | KSVVWQKIKA | TVFDDCKKEG | EWKIMLLDEF | TTKLLASCCK | 
    100:
    MTDLLEEGIT | VVENIYKNRE | PVRQMKALYF | ITPTSKSVDC | FLHDFASKSE | 
    150:
    NKYKAAYIYF | TDFCPDNLFN | KIKASCSKSI | RRCKEINISF | IPHESQVYTL | 
    200:
    DVPDAFYYCY | SPDPGNAKGK | DAIMETMADQ | IVTVCATLDE | NPGVRYKSKP | 
    250:
    LDNASKLAQL | VEKKLEDYYK | IDEKSLIKGK | THSQLLIIDR | GFDPVSTVLH | 
    300:
    ELTFQAMAYD | LLPIENDTYK | YKTDGKEKEA | ILEEEDDLWV | RIRHRHIAVV | 
    350:
    LEEIPKLMKE | ISSTKKATEG | KTSLSALTQL | MKKMPHFRKQ | ITKQVVHLNL | 
    400:
    AEDCMNKFKL | NIEKLCKTEQ | DLALGTDAEG | QKVKDSMRVL | LPVLLNKNHD | 
    450:
    NCDKIRAILL | YIFSINGTTE | ENLDRLIQNV | KIENESDMIR | NWSYLGVPIV | 
    500:
    PQSQQGKPLR | KDRSAEETFQ | LSRWTPFIKD | IMEDAIDNRL | DSKEWPYCSQ | 
    550:
    CPAVWNGSGA | VSARQKPRAN | YLEDRKNGSK | LIVFVIGGIT | YSEVRCAYEV | 
    592:
    SQAHKSCEVI | IGSTHVLTPK | KLLDDIKMLN | KPKDKVSLIK | DE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    String:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Syntaxin-binding protein 3
    ELISA Kit for Human Syntaxin-binding protein 3
    CLIA Kit for Human Syntaxin-binding protein 3
    CLIA Kit for Human Syntaxin-binding protein 3
    Polyclonal Antibody for Human Syntaxin-binding protein 3
    Polyclonal Antibody for Human Syntaxin-binding protein 3
    Monoclonal Antibody for Human Syntaxin-binding protein 3
    Monoclonal Antibody for Human Syntaxin-binding protein 3
    Protein for Human Syntaxin-binding protein 3
    Protein for Human Syntaxin-binding protein 3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A murine neural-specific homolog corrects cholinergic defects in Caenorhabditis elegans unc-18 mutants."
      Gengyo-Ando K. , Kitayama H. , Mukaida M. , Ikawa Y.
      J. Neurosci.16:6695-6702(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS GLY-433 AND GLY-546
      tissue: Brain.
    2. 2.
      "Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion."
      Reed G.L. , Houng A.K. , Fitzgerald M.L.
      Blood93:2617-2626(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH STX4;SUBCELLULAR LOCATION;PHOSPHORYLATION
      tissue: Leukemic T-cell.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Thalamus.
      tissue: Tongue.
    4. 4.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Testis.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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