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Index > Protein center > Trpc6(Gene name) > Mouse
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  • Trpc6 (Gene name),
  • Short transient receptor potential channel 6 (Protein name ),  TRPC6_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Trpc6(Trp6;Trrp6);
    Protein name:
    Short transient receptor potential channel 6(TrpC6);
    Alternative:
    Transient receptor protein 6(TRP-6);Calcium entry channel;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with MX1 and RNF24.
    Function:
    Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    930
    Sequence:
    50:
    MSQSPRFVTR | RGGSLKAAPG | AGTRRNESQD | YLLMDELGDD | GYPQLPLPPY | 
    100:
    GYYPSFRGNE | NRLTHRRQTI | LREKGRRLAN | RGPAYMFNDH | STSLSIEEER | 
    150:
    FLDAAEYGNI | PVVRKMLEEC | HSLNVNCVDY | MGQNALQLAV | ANEHLEITEL | 
    200:
    LLKKENLSRV | GDALLLAISK | GYVRIVEAIL | NHPAFAEGKR | LATSPSQSEL | 
    250:
    QQDDFYAYDE | DGTRFSHDVT | PIILAAHCQE | YEIVHTLLRK | GARIERPHDY | 
    300:
    FCKCTECSQK | QKHDSFSHSR | SRINAYKGLA | SPAYLSLSSE | DPVMTALELS | 
    350:
    NELAVLANIE | KEFKNDYRKL | SMQCKDFVVG | LLDLCRNTEE | VEAILNGDAE | 
    400:
    TRQPGDFGRP | NLSRLKLAIK | YEVKKFVAHP | NCQQQLLSIW | YENLSGLRQQ | 
    450:
    TMAVKFLVVL | AVAIGLPFLA | LIYWCAPCSK | MGKILRGPFM | KFVAHAASFT | 
    500:
    IFLGLLVMNA | ADRFEGTKLL | PNETSTDNAR | QLFRMKTSCF | SWMEMLIISW | 
    550:
    VIGMIWAECK | EIWTQGPKEY | LFELWNMLDF | GMLAIFAASF | IARFMAFWHA | 
    600:
    SKAQSIIDAN | DTLKDLTKVT | LGDNVKYYNL | ARIKWDPTDP | QIISEGLYAI | 
    650:
    AVVLSFSRIA | YILPANESFG | PLQISLGRTV | KDIFKFMVIF | IMVFVAFMIG | 
    700:
    MFNLYSYYIG | AKQNEAFTTV | EESFKTLFWA | IFGLSEVKSV | VINYNHKFIE | 
    750:
    NIGYVLYGVY | NVTMVIVLLN | MLIAMINSSF | QEIEDDADVE | WKFARAKLWF | 
    800:
    SYFEEGRTLP | VPFNLVPSPK | SLLYLLLKFK | KWMCELIQGQ | KQGFQEDAEM | 
    850:
    NKRNEEKKFG | ISGSHEDLSK | FSLDKNQLAH | NKQSSTRSSE | DYHLNSFSNP | 
    900:
    PRQYQKIMKR | LIKRYVLQAQ | IDKESDEVNE | GELKEIKQDI | SSLRYELLEE | 
    930:
    KSQNTEDLAE | LIRKLGERLS | LEPKLEESRR | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse TrpC6
    ELISA Kit for Mouse TrpC6
    ELISA Kit for Mouse TrpC6
    CLIA Kit for Mouse TrpC6
    CLIA Kit for Mouse TrpC6
    CLIA Kit for Mouse TrpC6
    Polyclonal Antibody for Mouse TrpC6
    Polyclonal Antibody for Mouse TrpC6
    Polyclonal Antibody for Mouse TrpC6
    Monoclonal Antibody for Mouse TrpC6
    Monoclonal Antibody for Mouse TrpC6
    Monoclonal Antibody for Mouse TrpC6
    Protein for Mouse TrpC6
    Protein for Mouse TrpC6
    Protein for Mouse TrpC6

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein."
      Boulay G. , Zhu X. , Peyton M. , Jiang M. , Hurst R. , Stefani E. , Birnbaumer L.
      J. Biol. Chem.272:29672-29680(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "Search for oncogenic regulators in an autocrine tumor model using differential display PCR: identification of novel candidate genes including the calcium channel mtrp6."
      Buess M. , Engler O. , Hirsch H.H. , Moroni C.
      Oncogene18:1487-1494(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: DBA/2.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Embryo.
    5. 5.
      "trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry."
      Zhu X. , Jiang M. , Peyton M. , Boulay G. , Hurst R. , Stefani E. , Birnbaumer L.
      Cell85:661-671(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 631-739
      tissue: Brain.
    6. 6.
      "Regulation of TRPC6 channel activity by tyrosine phosphorylation."
      Hisatsune C. , Kuroda Y. , Nakamura K. , Inoue T. , Nakamura T. , Michikawa T. , Mizutani A. , Mikoshiba K.
      J. Biol. Chem.279:18887-18894(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY FYN
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