UBE2B ELISA Kit for Rabbit(Oryctolagus cuniculus) | EIAab.comUBE2B ELISA Kit for Rabbit(Oryctolagus cuniculus)

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Index > Protein center > UBE2B(Gene name) > Rabbit

UBE2B (Gene name),

Ubiquitin-conjugating enzyme E2 B (Protein name ), UBE2B_RABIT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

UBE2B(RAD6B);

Protein name:

Ubiquitin-conjugating enzyme E2 B;

Alternative:

Ubiquitin carrier protein B;RAD6 homolog B(HR6B);Ubiquitin-protein ligase B;Ubiquitin-conjugating enzyme E2(14k);

Organism:

Rabbit (Oryctolagus cuniculus).

General Annotation

Sub Unit:

Interacts with RAD18, UBR2 and WAC.

Function:

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.

Subcellular Location:

Cell membrane Nucleus In peripheral neurons, expressed both at the plasma membrane and in nuclei.

Protein Attributes:

Sequence length:

152

Sequence:

50:

100:

150:

152:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Ocu.1605

SMR:

P63148

Pfam:

PF00179

Uniprot:

P63148

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ELISA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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E1063h

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ELISA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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E1063r

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ELISA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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E1063b

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ELISA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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E1063m

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ELISA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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CLIA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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U1063r

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CLIA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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U1063b

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96T

CLIA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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U1063h

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96T

CLIA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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U1063m

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CLIA Kit for Rabbit Ubiquitin-conjugating enzyme E2 B

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Polyclonal Antibody for Rabbit Ubiquitin-conjugating enzyme E2 B

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P1063Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rabbit Ubiquitin-conjugating enzyme E2 B

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P1063Rb-r

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Polyclonal Antibody for Rabbit Ubiquitin-conjugating enzyme E2 B

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P1063Rb-h

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Polyclonal Antibody for Rabbit Ubiquitin-conjugating enzyme E2 B

Monoclonal Antibody for Rabbit Ubiquitin-conjugating enzyme E2 B

Protein for Rabbit Ubiquitin-conjugating enzyme E2 B

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"A rabbit reticulocyte ubiquitin carrier protein that supports ubiquitin-dependent proteolysis (E214k) is homologous to the yeast DNA repair gene RAD6."
Wing S.S. , Dumas F. , Banville D.
J. Biol. Chem.267:6495-6501(1992) [PubMed] [Europe PMC] [Abstract]

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