Ube2b ELISA Kit for Rat(Rattus norvegicus) | EIAab.comUbe2b ELISA Kit for Rat(Rattus norvegicus)

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Ube2b (Gene name),

Ubiquitin-conjugating enzyme E2 B (Protein name ), UBE2B_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ube2b(Rad6b);

Protein name:

Ubiquitin-conjugating enzyme E2 B;

Alternative:

Ubiquitin carrier protein B;RAD6 homolog B(HR6B);Ubiquitin-protein ligase B;Ubiquitin-conjugating enzyme E2(14k);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with RAD18, UBR2 and WAC.

Function:

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation (By similarity). In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.

Subcellular Location:

Cell membrane Nucleus In peripheral neurons, expressed both at the plasma membrane and in nuclei.

Protein Attributes:

Sequence length:

152

Sequence:

50:

100:

150:

152:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000016742

SMR:

P63149

KEGG:

rno:81816

Pfam:

PF00179

UniGene:

Rn.20766

String:

P63149

Uniprot:

P63149

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ELISA Kit for Rat Ubiquitin-conjugating enzyme E2 B

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E1063h

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96T

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ELISA Kit for Rat Ubiquitin-conjugating enzyme E2 B

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E1063r

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ELISA Kit for Rat Ubiquitin-conjugating enzyme E2 B

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E1063b

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96T

ELISA Kit for Rat Ubiquitin-conjugating enzyme E2 B

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E1063m

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96T

ELISA Kit for Rat Ubiquitin-conjugating enzyme E2 B

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CLIA Kit for Rat Ubiquitin-conjugating enzyme E2 B

Cat.:

U1063r

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96T

CLIA Kit for Rat Ubiquitin-conjugating enzyme E2 B

Cat.:

U1063b

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96T

CLIA Kit for Rat Ubiquitin-conjugating enzyme E2 B

Cat.:

U1063h

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Packing:

96T

CLIA Kit for Rat Ubiquitin-conjugating enzyme E2 B

Cat.:

U1063m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Ubiquitin-conjugating enzyme E2 B

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Polyclonal Antibody for Rat Ubiquitin-conjugating enzyme E2 B

Cat.:

P1063Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Ubiquitin-conjugating enzyme E2 B

Cat.:

P1063Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat Ubiquitin-conjugating enzyme E2 B

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P1063Rb-h

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Polyclonal Antibody for Rat Ubiquitin-conjugating enzyme E2 B

Monoclonal Antibody for Rat Ubiquitin-conjugating enzyme E2 B

Protein for Rat Ubiquitin-conjugating enzyme E2 B

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"A rabbit reticulocyte ubiquitin carrier protein that supports ubiquitin-dependent proteolysis (E214k) is homologous to the yeast DNA repair gene RAD6."
Wing S.S. , Dumas F. , Banville D.
J. Biol. Chem.267:6495-6501(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
2.

"14-kDa ubiquitin-conjugating enzyme: structure of the rat gene and regulation upon fasting and by insulin."
Wing S.S. , Banville D.
Am. J. Physiol.267:E39-E48(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY
3.

"Isolation of a ubiquitin-conjugating enzyme gene induced following cerebral ischemia from the rat brain using modified subtractive hybridization and differential screening."
Chen D. , Graham S.H. , Jing K. , Simon R.P. , Chen J.
Submitted (1999-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
tissue: Brain.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Heart.
5.

"The N-end rule ubiquitin-conjugating enzyme, HR6B, is up-regulated by nerve growth factor and required for neurite outgrowth."
Kavakebi P. , Hausott B. , Tomasino A. , Ingorokva S. , Klimaschewski L.
Mol. Cell. Neurosci.29:559-568(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;SUBCELLULAR LOCATION;FUNCTION

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