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Index > Protein center > USF1(Gene name) > Human
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  • USF1 (Gene name),
  • Upstream stimulatory factor 1 (Protein name ),  USF1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    USF1(BHLHB11;USF);
    Protein name:
    Upstream stimulatory factor 1;
    Alternative:
    Major late transcription factor 1;Class B basic helix-loop-helix protein 11(bHLHb11);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an homodimer or a heterodimer (USF1/USF2). Interacts with varicella-zoster virus IE62 protein.
    Function:
    Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    310
    Sequence:
    50:
    MKGQQKTAET | EEGTVQIQEG | AVATGEDPTS | VAIASIQSAA | TFPDPNVKYV | 
    100:
    FRTENGGQVM | YRVIQVSEGQ | LDGQTEGTGA | ISGYPATQSM | TQAVIQGAFT | 
    150:
    SDDAVDTEGT | AAETHYTYFP | STAVGDGAGG | TTSGSTAAVV | TTQGSEALLG | 
    200:
    QATPPGTGQF | FVMMSPQEVL | QGGSQRSIAP | RTHPYSPKSE | APRTTRDEKR | 
    250:
    RAQHNEVERR | RRDKINNWIV | QLSKIIPDCS | MESTKSGQSK | GGILSKACDY | 
    300:
    IQELRQSNHR | LSEELQGLDQ | LQLDNDVLRQ | QVEDLKNKNL | LLRAQLRHHG | 
    310:
    LEVVIKNDSN | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    MIM:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Upstream stimulatory factor 1
    Cat.:
    E15130m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Upstream stimulatory factor 1
    Cat.:
    E15130h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Upstream stimulatory factor 1
    Cat.:
    E15130b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Upstream stimulatory factor 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Upstream stimulatory factor 1
    Cat.:
    U15130b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Upstream stimulatory factor 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Upstream stimulatory factor 1
    Cat.:
    U15130m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Upstream stimulatory factor 1
    Cat.:
    U15130h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Upstream stimulatory factor 1
    Cat.:
    P15130Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Upstream stimulatory factor 1
    Polyclonal Antibody for Human Upstream stimulatory factor 1
    Cat.:
    P15130Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Upstream stimulatory factor 1
    Monoclonal Antibody for Human Upstream stimulatory factor 1
    Monoclonal Antibody for Human Upstream stimulatory factor 1
    Monoclonal Antibody for Human Upstream stimulatory factor 1
    Monoclonal Antibody for Human Upstream stimulatory factor 1
    Protein for Human Upstream stimulatory factor 1
    Protein for Human Upstream stimulatory factor 1
    Protein for Human Upstream stimulatory factor 1
    Protein for Human Upstream stimulatory factor 1

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    Precision
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    Linearity
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    References
    1. 1.
      "The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer."
      Gregor P.D. , Sawadogo M. , Roeder R.G.
      Genes Dev.4:1730-1740(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 1-25
    2. 2.
      "Human USF1 genomic sequence."
      Fukamizu A.
      Submitted (1998-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Cloning and characterization of a novel splicing isoform of USF1."
      Saito T. , Oishi T. , Yanai K. , Shimamoto Y. , Fukamizu A.
      Submitted (2002-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);ALTERNATIVE SPLICING
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Testis.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Fetal kidney.
    6. 6.
      SeattleSNPs variation discovery resource
      Submitted (2004-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Kidney.
    10. 10.
      "Transcription factor USF, expressed during the entire phase of Varicella-zoster virus infection, interacts physically with the major viral transactivator IE62 and plays a significant role in virus replication."
      Rahaus M. , Desloges N. , Yang M. , Ruyechan W.T. , Wolff M.H.
      J. Gen. Virol.84:2957-2967(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VARICELLA-ZOSTER VIRUS IE62 PROTEIN
    11. 11.
      "Structure and function of the b/HLH/Z domain of USF."
      Ferre-D'Amare A.R. , Pognonec P. , Roeder R.G. , Burley S.K.
      EMBO J.13:180-189(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 197-260
    12. 12.
      "Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)."
      Pajukanta P. , Lilja H.E. , Sinsheimer J.S. , Cantor R.M. , Lusis A.J. , Gentile M. , Duan X.J. , Soro-Paavonen A. , Naukkarinen J. , Saarela J. , Laakso M. , Ehnholm C. , Taskinen M.-R. , Peltonen L.
      Nat. Genet.36:371-376(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN HYPLIP1
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