ATP6V0C ELISA Kit for Human(Homo sapiens) | EIAab.comATP6V0C ELISA Kit for Human(Homo sapiens)

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ATP6V0C (Gene name),

V-type proton ATPase 16 kDa proteolipid subunit (Protein name ), VATL_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ATP6V0C(ATP6C;ATP6L;ATPL);

Protein name:

V-type proton ATPase 16 kDa proteolipid subunit(V-ATPase 16 kDa proteolipid subunit);

Alternative:

Vacuolar proton pump 16 kDa proteolipid subunit;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein; which is present as a hexamer that forms the proton-conducting pore). Interacts with LASS2. Interacts with HTLV-1 accessory protein p12I. Interacts with RNF182; this interaction leads to ubiquitination and degradation via the proteasome pathway.

Function:

Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subcellular Location:

Vacuole membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

155

Sequence:

50:

100:

150:

155:

ILSTK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.389107

Pfam:

PF00137

STRING:

9606.ENSP00000329757

KEGG:

hsa:527

String:

P27449

SMR:

P27449

MIM:

108745

Uniprot:

P27449

FOR

ELISA Kit for Human V-ATPase 16 kDa proteolipid subunit

CLIA Kit for Human V-ATPase 16 kDa proteolipid subunit

Polyclonal Antibody for Human V-ATPase 16 kDa proteolipid subunit

Monoclonal Antibody for Human V-ATPase 16 kDa proteolipid subunit

Protein for Human V-ATPase 16 kDa proteolipid subunit

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"CpG island in the region of an autosomal dominant polycystic kidney disease locus defines the 5' end of a gene encoding a putative proton channel."
Gillespie G.A.J. , Somlo S. , Germino G.G. , Weinstat-Saslow D. , Reeders S.T.
Proc. Natl. Acad. Sci. U.S.A.88:4289-4293(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Muscle.
tissue: Skin.
5.

"Vacuolar type H(+)-ATPase genes: presence of four genes including pseudogenes for the 16-kDa proteolipid subunit in the human genome."
Hasebe M. , Hanada H. , Moriyama Y. , Maeda M. , Futai M.
Biochem. Biophys. Res. Commun.183:856-863(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 28-155
6.

"Mapping of the intermolecular association of human T cell leukaemia/lymphotropic virus type I p12I and the vacuolar H+-ATPase 16 kDa subunit protein."
Koralnik I.J. , Mulloy J.C. , Andresson T. , Fullen J. , Franchini G.
J. Gen. Virol.76:1909-1916(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTLV-1 ACCESSORY PROTEIN P12I
7.

"Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1."
Pan H. , Qin W.-X. , Huo K.-K. , Wan D.-F. , Yu Y. , Xu Z.-G. , Hu Q.-D. , Gu K.T. , Zhou X.-M. , Jiang H.-Q. , Zhang P.-P. , Huang Y. , Li Y.-Y. , Gu J.-R.
Genomics77:58-64(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LASS2
8.

"A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation."
Liu Q.Y. , Lei J.X. , Sikorska M. , Liu R.
Mol. Neurodegener.3:4-4(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF182;UBIQUITINATION
9.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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