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Index > Protein center > ZC3H12D(Gene name) > Human
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  • ZC3H12D (Gene name),
  • Probable ribonuclease ZC3H12D (Protein name ),  ZC12D_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ZC3H12D(C6orf95;MCPIP4;TFL);
    Protein name:
    Probable ribonuclease ZC3H12D;
    Alternative:
    Transformed follicular lymphoma;MCP-induced protein 4;p34;Zinc finger CCCH domain-containing protein 12D;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation.
    Subcellular Location:
    Isoform 3 Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    527
    Sequence:
    50:
    MEHPSKMEFF | QKLGYDREDV | LRVLGKLGEG | ALVNDVLQEL | IRTGSRPGAL | 
    100:
    EHPAAPRLVP | RGSCGVPDSA | QRGPGTALEE | DFRTLASSLR | PIVIDGSNVA | 
    150:
    MSHGNKETFS | CRGIKLAVDW | FRDRGHTYIK | VFVPSWRKDP | PRADTPIREQ | 
    200:
    HVLAELERQA | VLVYTPSRKV | HGKRLVCYDD | RYIVKVAYEQ | DGVIVSNDNY | 
    250:
    RDLQSENPEW | KWFIEQRLLM | FSFVNDRFMP | PDDPLGRHGP | SLSNFLSRKP | 
    300:
    KPPEPSWQHC | PYGKKCTYGI | KCKFYHPERP | HHAQLAVADE | LRAKTGARPG | 
    350:
    AGAEEQRPPR | APGGSAGARA | APREPFAHSL | PPARGSPDLA | ALRGSFSRLA | 
    400:
    FSDDLGPLGP | PLPVPACSLT | PRLGGPDWVS | AGGRVPGPLS | LPSPESQFSP | 
    450:
    GDLPPPPGLQ | LQPRGEHRPR | DLHGDLLSPR | RPPDDPWARP | PRSDRFPGRS | 
    500:
    VWAEPAWGDG | ATGGLSVYAT | EDDEGDARAR | ARIALYSVFP | RDQVDRVMAA | 
    527:
    FPELSDLARL | ILLVQRCQSA | GAPLGKP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    MIM:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Probable ribonuclease ZC3H12D
    ELISA Kit for Human Probable ribonuclease ZC3H12D
    CLIA Kit for Human Probable ribonuclease ZC3H12D
    CLIA Kit for Human Probable ribonuclease ZC3H12D
    Polyclonal Antibody for Human Probable ribonuclease ZC3H12D
    Polyclonal Antibody for Human Probable ribonuclease ZC3H12D
    Monoclonal Antibody for Human Probable ribonuclease ZC3H12D
    Monoclonal Antibody for Human Probable ribonuclease ZC3H12D
    Protein for Human Probable ribonuclease ZC3H12D
    Protein for Human Probable ribonuclease ZC3H12D

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Inhibition of G(1) to S phase progression by a novel zinc finger protein P58(TFL) at P-bodies."
      Minagawa K. , Katayama Y. , Nishikawa S. , Yamamoto K. , Sada A. , Okamura A. , Shimoyama M. , Matsui T.
      Mol. Cancer Res.7:880-889(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;VARIANT LEU-53
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT LEU-53
      tissue: Spleen.
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain cortex.
    5. 5.
      "Deregulation of a possible tumour suppressor gene, ZC3H12D, by translocation of IGK@ in transformed follicular lymphoma with t(2;6)(p12;q25)."
      Minagawa K. , Yamamoto K. , Nishikawa S. , Ito M. , Sada A. , Yakushijin K. , Okamura A. , Shimoyama M. , Katayama Y. , Matsui T.
      Br. J. Haematol.139:161-163(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION;INVOLVEMENT IN DIFFUSE LARGE B-CELL LYMPHOMA
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;VARIANT ARG-106
    7. 7.
      "A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages."
      Liang J. , Wang J. , Azfer A. , Song W. , Tromp G. , Kolattukudy P.E. , Fu M.
      J. Biol. Chem.283:6337-6346(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
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