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Index > Protein center > Sfn(Gene name) > Mouse
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  • Sfn (Gene name),
  • 14-3-3 protein sigma (Protein name ),  1433S_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Sfn(Mkrn3);
    Protein name:
    14-3-3 protein sigma;
    Alternative:
    Stratifin;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with GAB2 (By similarity). Interacts with KRT17. Interacts with SAMSN1.
    Function:
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
    Subcellular Location:
    Cytoplasm Nucleus Secreted May be secreted by a non-classical secretory pathway.
    Protein Attributes:
    Sequence length:
    248
    Sequence:
    50:
    MERASLIQKA | KLAEQAERYE | DMAAFMKSAV | EKGEELSCEE | RNLLSVAYKN | 
    100:
    VVGGQRAAWR | VLSSIEQKSN | EEGSEEKGPE | VKEYREKVET | ELRGVCDTVL | 
    150:
    GLLDSHLIKG | AGDAESRVFY | LKMKGDYYRY | LAEVATGDDK | KRIIDSARSA | 
    200:
    YQEAMDISKK | EMPPTNPIRL | GLALNFSVFH | YEIANSPEEA | ISLAKTTFDE | 
    248:
    AMADLHTLSE | DSYKDSTLIM | QLLRDNLTLW | TADSAGEEGG | EAPEEPQS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse 14-3-3 protein sigma
    Cat.:
    E15106m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse 14-3-3 protein sigma
    Cat.:
    E15106h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse 14-3-3 protein sigma
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse 14-3-3 protein sigma
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse 14-3-3 protein sigma
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse 14-3-3 protein sigma
    Cat.:
    U15106h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse 14-3-3 protein sigma
    Polyclonal Antibody for Mouse 14-3-3 protein sigma
    Polyclonal Antibody for Mouse 14-3-3 protein sigma
    Monoclonal Antibody for Mouse 14-3-3 protein sigma
    Monoclonal Antibody for Mouse 14-3-3 protein sigma
    Monoclonal Antibody for Mouse 14-3-3 protein sigma
    Protein for Mouse 14-3-3 protein sigma
    Protein for Mouse 14-3-3 protein sigma
    Protein for Mouse 14-3-3 protein sigma

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Karpitskiy V.V. , Shaw A.S.
      Submitted (1998-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: FVB/N.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Heart.
      tissue: Stomach.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      Lubec G. , Kang S.U. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-12; 42-49; 61-68 AND 215-224;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      strain: OF1.
      tissue: Brain.
      tissue: Hippocampus.
    6. 6.
      "A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth."
      Kim S. , Wong P. , Coulombe P.A.
      Nature441:362-365(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH KRT17;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SAMSN1
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