HLA-A ELISA Kit for Human(Homo sapiens) | EIAab.comHLA-A ELISA Kit for Human(Homo sapiens)

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HLA-A (Gene name),

HLA class I histocompatibility antigen, A-2 alpha chain (Protein name ), 1A02_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HLA-A(HLAA);

Protein name:

HLA class I histocompatibility antigen, A-2 alpha chain;

Alternative:

MHC class I antigen A*2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Dimer of alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein. Interacts with HTLV-1 accessory protein p12I.

Function:

Involved in the presentation of foreign antigens to the immune system.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

365

Sequence:

50:

100:

150:

200:

250:

300:

350:

365:

DSAQGSDVSL | TACKV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P01892

UniGene:

Hs.181244

KEGG:

hsa:100507703

Pfam:

PF07654

SMR:

P01892

MIM:

142800

Uniprot:

P01892

FOR

ELISA Kit for Human HLA class I histocompatibility antigen, A-2 alpha chain

CLIA Kit for Human HLA class I histocompatibility antigen, A-2 alpha chain

Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-2 alpha chain

Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-2 alpha chain

Protein for Human HLA class I histocompatibility antigen, A-2 alpha chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and complete sequence of an HLA-A2 gene: analysis of two HLA-A alleles at the nucleotide level."
Koller B.H. , Orr H.T.
J. Immunol.134:2727-2733(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE A*02:01)
2.

"Three new class I HLA alleles: structure of mRNAs and alternative mechanisms of processing."
Cianetti L. , Testa U. , Scotto L. , la Valle R. , Simeone A. , Boccoli G. , Giannella G. , Peschle C. , Boncinelli E.
Immunogenetics29:80-91(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*02:01)
3.

"Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification."
Ennis P.D. , Zemmour J. , Salter R.D. , Parham P.
Proc. Natl. Acad. Sci. U.S.A.87:2833-2837(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*02:01)
4.

"Comparison of HLA class I gene sequences. Derivation of locus-specific oligonucleotide probes specific for HLA-A, HLA-B, and HLA-C genes."
Davidson W.F. , Kress M. , Khoury G. , Jay G.
J. Biol. Chem.260:13414-13423(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 91-365
5.

"Unusual HLA-B alleles in two tribes of Brazilian Indians."
Belich M.P. , Madrigal J.A. , Hildebrand W.H. , Zemmour J. , Williams R.C. , Luz R. , Petzl-Erler M.L. , Parham P.
Nature357:326-329(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELES A*02:01; A*02:11 AND A*02:12)
6.

"Unusual RNA splicing generates a secreted form of HLA-A2 in a mutagenized B lymphoblastoid cell line."
Krangel M.S.
EMBO J.4:1205-1210(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 39-365 (ALLELE A*02:01)
7.

"Comparison of amino acid sequences of two human histocompatibility antigens, HLA-A2 and HLA-B7: location of putative alloantigenic sites."
Orr H.T. , Lopez de Castro J.A. , Parham P. , Ploegh H.L. , Strominger J.L.
Proc. Natl. Acad. Sci. U.S.A.76:4395-4399(1979) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-295 (ALLELE A*02:01)
8.

"Structure of crossreactive human histocompatibility antigens HLA-A28 and HLA-A2: possible implications for the generation of HLA polymorphism."
Lopez de Castro J.A. , Strominger J.L. , Strong D.M. , Orr H.T.
Proc. Natl. Acad. Sci. U.S.A.79:3813-3817(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION (ALLELE A*02:01)
9.

"HLA class I allele (HLA-A2) expression defect associated with a mutation in its enhancer B inverted CAT box in two families."
Balas A. , Garcia-Sanchez F. , Gomez-Reino F. , Vicario J.L.
Hum. Immunol.41:69-73(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE A*02:01)
tissue: Blood.
10.

Balas A.
Submitted (2003-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
11.

"Confirmation of HLA-A*0201."
Cox S.T.
Submitted (2003-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*02:01)
12.

"DNA sequences of the genes that encode the CTL-defined HLA-A2 variants M7 and DK1."
Mattson D.H. , Handy D.E. , Bradley D.A. , Coligan J.E. , Cowan E.P. , Biddison W.E.
Immunogenetics26:190-192(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-298 (ALLELES A*02:02 AND A*02:03)
13.

"Multiple genetic mechanisms have contributed to the generation of the HLA-A2/A28 family of class I MHC molecules."
Holmes N. , Ennis P. , Wan A.M. , Denney D.W. , Parham P.
J. Immunol.139:936-941(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELES A*02:03 AND A*02:05)
14.

Domena J.D.
Submitted (1993-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELES A*02:03 AND A*02:05)
15.

"Structure of the HLA-A*0204 antigen, found in South American Indians. Spatial clustering of HLA-A2 subtype polymorphism."
Castano A.R. , Lopez de Castro J.A.
Immunogenetics34:281-285(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 9-365 (ALLELE A*02:04)
16.

"New recombinant HLA-B alleles in a tribe of South American Amerindians indicate rapid evolution of MHC class I loci."
Watkins D.I. , McAdam S.N. , Liu X. , Stang C.R. , Milford E.L. , Levine C.G. , Garber T.L. , Dogon A.L. , Lord C.I. , Ghim S.H. , Troup G.M. , Hughes A.L. , Letvin N.L.
Nature357:329-333(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 9-365 (ALLELE A*02:04)
17.

"Diversity and diversification of HLA-A,B,C alleles."
Parham P. , Lawlor D.A. , Lomen C.E. , Ennis P.D.
J. Immunol.142:3937-3950(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*02:06)
18.

"Molecular analysis of an HLA-A2 functional variant CLA defined by cytolytic T lymphocytes."
Ezquerra A. , Domenech N. , van der Poel J. , Strominger J.L. , Vega M.A. , Lopez de Castro J.A.
J. Immunol.137:1642-1649(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE (ALLELE A*02:06)
19.

"Structural analysis of HLA-A2.4 functional variant KNE. Implications for the mapping of HLA-A2-specific T-cell epitopes."
Domenech N. , Ezquerra A. , Castano R. , Lopez de Castro J.A.
Immunogenetics27:196-202(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE (ALLELE A*02:07)
20.

"Molecular analysis of HLA-A2.4 functional variant KLO: close structural and evolutionary relatedness to the HLA-A2.2 subtype."
Domenech N. , Castano R. , Goulmy E. , Lopez de Castro J.A.
Immunogenetics28:143-152(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE (ALLELE A*02:08)
21.

"An HLA-A2 population variant with structural polymorphism in the alpha 3 region."
Castano R. , Ezquerra A. , Domenech N. , Lopez de Castro J.A.
Immunogenetics27:345-355(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE (ALLELE A*02:09)
22.

"An Oriental HLA-A2 subtype is closely related to a subset of Caucasoid HLA-A2 alleles."
Epstein H. , Kennedy L. , Holmes N.
Immunogenetics29:112-116(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*02:10)
23.

"Structure of the HLA-A*0211 (A2.5) subtype: further evidence for selection-driven diversification of HLA-A2 antigens."
Castano A.R. , Lopez de Castro J.A.
Immunogenetics35:344-346(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 9-365 (ALLELE A*02:11)
24.

"Primary structure of a new HLA-A2 subtype: HLA-A*0213."
Barber D.F. , Fernandez J.M. , Lopez de Castro J.A.
Immunogenetics39:378-378(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE A*02:13)
25.

"Identification of a novel HLA-A2 subtype, HLA-A*0216."
Barouch D. , Krausa P. , Bodmer J. , Browning M.J. , McMichael A.J.
Immunogenetics41:388-388(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE A*02:16)
26.

"A novel subtype of A2 (A*0217) isolated from the South American Indian B-cell line AMALA."
Selvakumar A. , Granja C.B. , Salazar M. , Alosco S.M. , Yunis E.J. , Dupont B.
Tissue Antigens45:343-347(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE A*02:17)
tissue: Blood.
27.

"A new A2 sequence HLA-A2K from Japanese."
Kashiwase K. , Tokunaga K. , Ishikawa Y. , Oohashi H. , Hashimoto M. , Akaza T. , Tadokoro K. , Juji T.
Submitted (1996-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*02:18)
tissue: Blood.
28.

"HLA-A*02 subtype distribution in Caucasians from northern Italy: identification of A*0220."
Fleischhauer K. , Zino E. , Mazzi B. , Severini G.M. , Benazzi E. , Bordignon C.
Tissue Antigens48:673-679(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE A*02:20)
tissue: Blood.
29.

"Nucleotide sequence of a novel HLA-A2 gene."
Szmania S. , Baxter-Lowe L.A.
Submitted (1996-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*02:21)
tissue: Blood.
30.

"Frequencies of HLA-A2 alleles in five U.S. population groups. Predominance Of A*02011 and identification of HLA-A*0231."
Ellis J.M. , Henson V. , Slack R. , Ng J. , Hartzman R.J. , Hurley C.K.
Hum. Immunol.61:334-340(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELE A*02:31)
31.

"A new HLA-A*02 allele, A*0234, detected by polymerase chain reaction using sequence-specific primers (PCR-SSP)."
Moses J.H. , Greville W.D. , Downes J. , McClenahan W. , Kennedy A. , Dunckley H.
Tissue Antigens55:175-177(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-298 (ALLELE A*02:34)
32.

"Seventeen more novel HLA-A locus alleles."
Ellis J. , Steiner N.K. , Kosman C. , Henson V. , Mitton W. , Koester R. , Ng J. , Hartzman R.J. , Hurley C.K.
Tissue Antigens55:369-373(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELES A*02:35; A*02:36 AND A*02:37)
33.

"Phosphoproteome of resting human platelets."
Zahedi R.P. , Lewandrowski U. , Wiesner J. , Wortelkamp S. , Moebius J. , Schuetz C. , Walter U. , Gambaryan S. , Sickmann A.
J. Proteome Res.7:526-534(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-356;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Platelet.
34.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
35.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-110
tissue: Liver.
36.

"Structure of the human class I histocompatibility antigen, HLA-A2."
Bjorkman P.J. , Saper M.A. , Samraoui B. , Bennett W.S. , Strominger J.L. , Wiley D.C.
Nature329:506-512(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF A*02:01
37.

"Free major histocompatibility complex class I heavy chain is preferentially targeted for degradation by human T-cell leukemia/lymphotropic virus type 1 p12(I) protein."
Johnson J.M. , Nicot C. , Fullen J. , Ciminale V. , Casareto L. , Mulloy J.C. , Jacobson S. , Franchini G.
J. Virol.75:6086-6094(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTLV-1 ACCESSORY PROTEIN P12I
38.

"Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation."
Hewitt E.W. , Duncan L. , Mufti D. , Baker J. , Stevenson P.G. , Lehner P.J.
EMBO J.21:2418-2429(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HUMAN HERPESVIRUS 8 MIR1 PROTEIN;UBIQUITINATION
39.

"A structural basis for immunodominant human T cell receptor recognition."
Stewart-Jones G.B.E. , McMichael A.J. , Bell J.I. , Stuart D.I. , Jones E.Y.
Nat. Immunol.4:657-663(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.4 ANGSTROMS) OF 25-300 OF HLA-A/B2M HETERODIMER IN COMPLEX WITH TRAC AND TRBC1;DISULFIDE BONDS
40.

"Refined structure of the human histocompatibility antigen HLA-A2 at 2.6-A resolution."
Saper M.A. , Bjorkman P.J. , Wiley D.C.
J. Mol. Biol.219:277-319(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF A*02:01
41.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] GLU-176;VARIANT [LARGE SCALE ANALYSIS] TRP-180;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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