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Index > Protein center > HLA-A(Gene name) > Human
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  • HLA-A (Gene name),
  • HLA class I histocompatibility antigen, A-68 alpha chain (Protein name ),  1A68_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    HLA-A(HLAA);
    Protein name:
    HLA class I histocompatibility antigen, A-68 alpha chain;
    Alternative:
    HLA class I histocompatibility antigen, A-28 alpha chain;Aw-68;MHC class I antigen A*68;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein.
    Function:
    Involved in the presentation of foreign antigens to the immune system.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    365
    Sequence:
    50:
    MAVMAPRTLV | LLLSGALALT | QTWAGSHSMR | YFYTSVSRPG | RGEPRFIAVG | 
    100:
    YVDDTQFVRF | DSDAASQRME | PRAPWIEQEG | PEYWDRNTRN | VKAQSQTDRV | 
    150:
    DLGTLRGYYN | QSEAGSHTIQ | MMYGCDVGSD | GRFLRGYRQD | AYDGKDYIAL | 
    200:
    KEDLRSWTAA | DMAAQTTKHK | WEAAHVAEQW | RAYLEGTCVE | WLRRYLENGK | 
    250:
    ETLQRTDAPK | THMTHHAVSD | HEATLRCWAL | SFYPAEITLT | WQRDGEDQTQ | 
    300:
    DTELVETRPA | GDGTFQKWVA | VVVPSGQEQR | YTCHVQHEGL | PKPLTLRWEP | 
    350:
    SSQPTIPIVG | IIAGLVLFGA | VITGAVVAAV | MWRRKSSDRK | GGSYSQAASS | 
    365:
    DSAQGSDVSL | TACKV
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain
    Protein for Human HLA class I histocompatibility antigen, A-68 alpha chain

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    References
    1. 1.
      "Multiple genetic mechanisms have contributed to the generation of the HLA-A2/A28 family of class I MHC molecules."
      Holmes N. , Ennis P. , Wan A.M. , Denney D.W. , Parham P.
      J. Immunol.139:936-941(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*68:02)
    2. 2.
      Domena J.D.
      Submitted (1993-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*68:02)
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE A*68:03)
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE A*68:08)
    5. 5.
      "Confirmation of HLA-A*68011."
      Cox S.T.
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE A*68:011)
      tissue: Blood.
    6. 6.
      "HLA-A*6817, identified in the Kolla Amerindians of north-west Argentina possesses a novel nucleotide substitution."
      Ramon D. , Scott I. , Cox S.T. , Pesoa S. , Vullo C. , Little A.-M. , Madrigal J.A.
      Tissue Antigens55:453-454(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE A*68:17)
    7. 7.
      Bei M. , Hurley C.K.
      Submitted (1997-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELE A*68:06)
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELE A*68:03)
      tissue: Blood.
    9. 9.
      Blasczyk R.
      Submitted (1997-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELE A*68:03)
      tissue: Blood.
    10. 10.
      Edson S.M. , Hurley C.K.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELE A*68:02)
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELES A*68:09 AND A*68:10)
    12. 12.
      "A novel HLA-A*6816 allele possible generated by a point mutation in a Chilean from Punta Arenas (Magellan Strait)."
      Gomez-Casado E. , Martinez-Laso J. , Gonzalez-Hevilla M. , Longas J. , Rubio I. , Silvera-Redondo C. , Garcia-Gomez A. , Lowy E. , Arnaiz-Villena A.
      Immunogenetics51:257-260(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 3-206 (ALLELE A*68:16)
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELES A*68:07 AND A*68:17)
    14. 14.
      "Exon shuffling in vivo can generate novel HLA class I molecules."
      Holmes N. , Parham P.
      EMBO J.4:2849-2854(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-297 (ALLELE A*68:01)
    15. 15.
      "Structure of crossreactive human histocompatibility antigens HLA-A28 and HLA-A2: possible implications for the generation of HLA polymorphism."
      Lopez de Castro J.A. , Strominger J.L. , Strong D.M. , Orr H.T.
      Proc. Natl. Acad. Sci. U.S.A.79:3813-3817(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-294 (A*68:01)
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-356;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Platelet.
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