HLA-B27 ELISA Kit for Human(Homo sapiens) | EIAab.comHLA-B27 ELISA Kit for Human(Homo sapiens)

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HLA-B27 (Gene name),

HLA class I histocompatibility antigen, B-27 alpha chain (Protein name ), 1B27_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HLA-B(HLAB);

Protein name:

HLA class I histocompatibility antigen, B-27 alpha chain;

Alternative:

MHC class I antigen B*27;

Organism:

HLA-B27 (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein.

Function:

Involved in the presentation of foreign antigens to the immune system.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

362

Sequence:

50:

100:

150:

200:

250:

300:

350:

362:

dsaqgsdvsl | ta

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07654

MIM:

106300

String:

P03989

UniGene:

Hs.654404

SMR:

P03989

Uniprot:

P03989

FOR

ELISA Kit for Human HLA class I histocompatibility antigen, B-27 alpha chain

Cat.:

E1857h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human HLA class I histocompatibility antigen, B-27 alpha chain

Cat.:

U1857h

Price:

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Manual:

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MSDS:

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Packing:

96T

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Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-27 alpha chain

Cat.:

P1857Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-27 alpha chain

Protein for Human HLA class I histocompatibility antigen, B-27 alpha chain

Cat.:

R1857h

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

12% SDS-PAGE analysis

wb1 wb2

Western blot - Anti-HLA-B27 antibody

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Organization, sequence and expression of the HLA-B27 gene: a molecular approach to analyze HLA and disease associations."
Weiss E.H. , Kuon W. , Doerner C. , Lang M. , Riethmueller G.
Immunobiology170:367-380(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE B*27:01)
2.

"Complete sequence of HLA-B27 cDNA identified through the characterization of structural markers unique to the HLA-A, -B, and -C allelic series."
Szoets H. , Riethmueller G. , Weiss E. , Meo T.
Proc. Natl. Acad. Sci. U.S.A.83:1428-1432(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 25-361 (ALLELE B*27:01)
3.

"Primary structure of papain-solubilized human histocompatibility antigen HLA-B27."
Ezquerra A. , Bragado R. , Vega M.A. , Strominger J.L. , Woody J. , Lopez de Castro J.A.
Biochemistry24:1733-1741(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-295 (B*27:01)
4.

"Gene conversion-like mechanisms may generate polymorphism in human class I genes."
Seemann G.H.A. , Rein R.S. , Brown C.S. , Ploegh H.L.
EMBO J.5:547-552(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELES B*27:01 AND B*27:02)
5.

"On the nucleotide sequences of B*2702 and B*2705."
Moses J.H. , Marsh S.G.E. , Arnett K.L. , Adams E.J. , Bodmer J.G. , Parham P.
Tissue Antigens46:50-53(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*27:02)
6.

"Structural analysis of an HLA-B27 functional variant: identification of residues that contribute to the specificity of recognition by cytolytic T lymphocytes."
Vega M.A. , Ezquerra A. , Rojo S. , Aparicio P. , Bragado R. , Lopez de Castro J.A.
Proc. Natl. Acad. Sci. U.S.A.82:7394-7398(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 86-107 AND 171-181 (B*27:02)
7.

"Molecular analysis of the variant alloantigen HLA-B27d (HLA-B*2703) identifies a unique single amino acid substitution."
Choo S.Y. , St John T. , Orr H.T. , Hansen J.A.
Hum. Immunol.21:209-219(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE B*27:03)
8.

"The nucleotide sequence of HLA-B*2704 reveals a new amino acid substitution in exon 4 which is also present in HLA-B*2706."
Rudwaleit M. , Bowness P. , Wordsworth P.
Immunogenetics43:160-162(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELES B*27:04 AND B*27:06)
9.

"Absence of polymorphism between HLA-B27 genomic exon sequences isolated from normal donors and ankylosing spondylitis patients."
Coppin H.L. , McDevitt H.O.
J. Immunol.137:2168-2172(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 25-298 (ALLELE B*27:05)
10.

"Nucleotide sequence of HLA-B*2706."
Vilches C. , de Pablo R. , Kreisler M.
Immunogenetics39:219-219(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*27:06)
11.

"A novel HLA-B27 allele maps B27 allospecificity to the region around position 70 in the alpha 1 domain."
Choo Y.S. , Fan L.A. , Hansen J.A.
J. Immunol.147:174-180(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*27:07)
12.

"The HLA-B7Qui antigen is encoded by a new subtype of HLA-B27 (B*2708)."
Hildebrand W.H. , Domena J.D. , Shen S.Y. , Marsh S.G.E. , Bunce M. , Guttridge M.G. , Darke C. , Parham P.
Tissue Antigens44:47-51(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*27:08)
13.

"Identification of a novel HLA-B27 subtype by restriction analysis of a cytotoxic gamma/delta T cell clone."
Del Porto P. , D'Amato M. , Fiorillo M.T. , Tuosto L. , Piccolella E. , Sorrentino R.
J. Immunol.153:3093-3100(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*27:09)
tissue: Blood.
14.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-110
tissue: Liver.
15.

"The three-dimensional structure of HLA-B27 at 2.1-A resolution suggests a general mechanism for tight peptide binding to MHC."
Madden D.R. , Gorga J.C. , Strominger J.L. , Wiley D.C.
Cell70:1035-1048(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 25-300
16.

"The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation."
Madden D.R. , Gorga J.C. , Strominger J.L. , Wiley D.C.
Nature353:321-325(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 25-300
17.

"HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations."
Hulsmeyer M. , Hillig R.C. , Volz A. , Ruhl M. , Schroder W. , Saenger W. , Ziegler A. , Uchanska-Ziegler B.
J. Biol. Chem.277:47844-47853(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 25-300
18.

"Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen."
Rognan D. , Scapozza L. , Folkers G. , Daser A.
Proc. Natl. Acad. Sci. U.S.A.92:753-757(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 115-206
19.

"HLA-B27 in the Greek Cypriot population: distribution of subtypes in patients with ankylosing spondylitis and other HLA-B27-related diseases. The possible protective role of B*2707."
Varnavidou-Nicolaidou A. , Karpasitou K. , Georgiou D. , Stylianou G. , Kokkofitou A. , Michalis C. , Constantina C. , Gregoriadou C. , Kyriakides G.
Hum. Immunol.65:1451-1454(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE;POSSIBLE PROTECTIVE ROLE OF ALLELE B*27:07
20.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] THR-65;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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