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Index > Protein center > HLA-B(Gene name) > Human
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  • HLA-B (Gene name),
  • HLA class I histocompatibility antigen, B-51 alpha chain (Protein name ),  1B51_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HLA-B(HLAB);
    Protein name:
    HLA class I histocompatibility antigen, B-51 alpha chain;
    Alternative:
    MHC class I antigen B*51;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein.
    Function:
    Involved in the presentation of foreign antigens to the immune system.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    362
    Sequence:
    50:
    MRVTAPRTVL | LLLWGAVALT | ETWAGSHSMR | YFYTAMSRPG | RGEPRFIAVG | 
    100:
    YVDDTQFVRF | DSDAASPRTE | PRAPWIEQEG | PEYWDRNTQI | FKTNTQTYRE | 
    150:
    NLRIALRYYN | QSEAGSHTWQ | TMYGCDVGPD | GRLLRGHNQY | AYDGKDYIAL | 
    200:
    NEDLSSWTAA | DTAAQITQRK | WEAAREAEQL | RAYLEGLCVE | WLRRHLENGK | 
    250:
    ETLQRADPPK | THVTHHPVSD | HEATLRCWAL | GFYPAEITLT | WQRDGEDQTQ | 
    300:
    DTELVETRPA | GDRTFQKWAA | VVVPSGEEQR | YTCHVQHEGL | PKPLTLRWEP | 
    350:
    SSQSTIPIVG | IVAGLAVLAV | VVIGAVVATV | MCRRKSSGGK | GGSYSQAASS | 
    362:
    DSAQGSDVSL | TA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    Pfam:
    SMR:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-51 alpha chain

    R&D Technical Data
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    Precision
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    Recovery
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    References
    1. 1.
      "Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification."
      Ennis P.D. , Zemmour J. , Salter R.D. , Parham P.
      Proc. Natl. Acad. Sci. U.S.A.87:2833-2837(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*51:01)
    2. 2.
      "HLA-B51 and HLA-Bw52 differ by only two amino acids which are in the helical region of the alpha 1 domain."
      Hayashi H. , Ennis P.D. , Ariga H. , Salter R.D. , Parham P. , Kano K. , Takiguchi M.
      J. Immunol.142:306-311(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE B*51:01)
    3. 3.
      "Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles."
      Pohla H. , Kuon W. , Tabaczewski P. , Doerner C. , Weiss E.H.
      Immunogenetics29:297-307(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE B*51:01)
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE B*51:04)
    5. 5.
      "A single amino acid substitution at residue 167 forms a novel HLA-B51 subtype."
      Kawaguchi G. , Nakayama S. , Nagao T. , Takiguchi M.
      Tissue Antigens42:39-41(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE B*51:03)
      tissue: Peripheral blood.
    6. 6.
      "Novel alleles HLA-B*7802 and B*51022: evidence for convergency in the HLA-B5 family."
      Prilliman K. , Steiner N.K. , Ellexson M. , Stewart D. , Lau M. , Terasaki P. , Hurley C.K. , Hildebrand W.H.
      Tissue Antigens47:49-57(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*51:02)
    7. 7.
      "Complete coding regions of two novel HLA-B alleles detected by phototyping (PCR-SSP) in the British Caucasoid population: B*5108 and B*5002."
      Vilches C. , Bunce M. , de Pablo R. , Murray A.K. , McIntyre C.A. , Kreisler M.
      Tissue Antigens50:38-41(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE B*51:08)
    8. 8.
      "The absence of disease-specific polymorphisms within the HLA-B51 gene that is the susceptible locus for Behcet's disease."
      Sano K. , Yabuki K. , Imagawa Y. , Shiina T. , Mizuki N. , Ohno S. , Kulski J.K. , Inoko H.
      Tissue Antigens58:77-82(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE B*51:01)
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE B*51:01)
    10. 10.
      "HLA class I alleles of LCL 721 and 174 x CEM.T2 (T2)."
      Steinle A. , Schendel D.J.
      Tissue Antigens44:268-270(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-206 (ALLELE B*51:01)
    11. 11.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3-362 (ALLELE B*51:01)
      tissue: Lymph.
    12. 12.
      "Three newly identified HLA-B alleles: B*5124, B*5306, B*5307 and confirmation of B*0809 and B*5606."
      Anholts J.D.H. , Kemps-Mols B. , Verduijn W. , Oudshoorn M. , Schreuder G.M.T.
      Tissue Antigens58:38-41(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELE B*51:24)
      tissue: Peripheral blood.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes."
      Maenaka K. , Maenaka T. , Tomiyama H. , Takiguchi M. , Stuart D.I. , Jones E.Y.
      J. Immunol.165:3260-3267(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 25-300 (B*51:01)
    15. 15.
      "New insights into the pathogenesis and therapy of Behcet's disease."
      Arayssi T. , Hamdan A.
      Curr. Opin. Pharmacol.4:183-188(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN BEHCET DISEASE
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