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Index > Protein center > HLA-B(Gene name) > Human
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  • HLA-B (Gene name),
  • HLA class I histocompatibility antigen, B-53 alpha chain (Protein name ),  1B53_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HLA-B(HLAB);
    Protein name:
    HLA class I histocompatibility antigen, B-53 alpha chain;
    Alternative:
    MHC class I antigen B*53;Bw-53;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein.
    Function:
    Involved in the presentation of foreign antigens to the immune system.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    362
    Sequence:
    50:
    MRVTAPRTVL | LLLWGAVALT | ETWAGSHSMR | YFYTAMSRPG | RGEPRFIAVG | 
    100:
    YVDDTQFVRF | DSDAASPRTE | PRAPWIEQEG | PEYWDRNTQI | FKTNTQTYRE | 
    150:
    NLRIALRYYN | QSEAGSHIIQ | RMYGCDLGPD | GRLLRGHDQS | AYDGKDYIAL | 
    200:
    NEDLSSWTAA | DTAAQITQRK | WEAARVAEQL | RAYLEGLCVE | WLRRYLENGK | 
    250:
    ETLQRADPPK | THVTHHPVSD | HEATLRCWAL | GFYPAEITLT | WQRDGEDQTQ | 
    300:
    DTELVETRPA | GDRTFQKWAA | VVVPSGEEQR | YTCHVQHEGL | PKPLTLRWEP | 
    350:
    SSQSTIPIVG | IVAGLAVLAV | VVIGAVVATV | MCRRKSSGGK | GGSYSQAASS | 
    362:
    DSAQGSDVSL | TA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    Pfam:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain
    Protein for Human HLA class I histocompatibility antigen, B-53 alpha chain

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    Precision
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    Recovery
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    References
    1. 1.
      "Allospecificities between HLA-Bw53 and HLA-B35 are generated by substitution of the residues associated with HLA-Bw4/Bw6 public epitopes."
      Hayashi H. , Ooba T. , Nakayama S. , Sekimata M. , Kano K. , Takiguchi M.
      Immunogenetics32:195-199(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE B*53:01)
    2. 2.
      "Generation of the HLA-B35, -B5, -B16, and B15 groups of alleles studied by intron 1 and 2 sequence analysis."
      Gomez-Casado E. , Vargas-Alarcon G. , Martinez-Laso J. , Perez-Blas M. , Granados J. , Layrisse Z. , Montoya F. , Varela P. , Arnaiz-Villena A.
      Immunogenetics46:469-476(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 5-206 (ALLELE B*53:01)
      tissue: Blood.
    3. 3.
      "Confirmation of HLA-B*5301."
      Cox S.T.
      Submitted (2007-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Blood.
    4. 4.
      "Human MHC class I antigen HLA-B*5302."
      Hurley C.K. , Hoyer R.J.
      Submitted (1996-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELE B*53:02)
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELES B*53:03 AND B*53:05)
    6. 6.
      "Routine HLA-B genotyping with PCR-sequence-specific oligonucleotides (PCR-SSO) detects eight new alleles: B*0807, B*0809, B*1551, B*3529, B*3532, B*4025, B*5304 and B*5508."
      Kennedy C.T. , Dodd R. , Le T. , Wallace R. , Ng G. , Greville W.D. , Kennedy A. , Taverniti A. , Moses J.H. , Clow N. , Watson N. , Dunckley H.
      Tissue Antigens55:266-270(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELE B*53:04)
    7. 7.
      "Confirmatory B*5305 sequence."
      Tait B. , Holdsworth R. , Cantwell L. , Boyle A. , Diviney M.
      Submitted (2000-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELE B*53:05)
    8. 8.
      "Three newly identified HLA-B alleles: B*5124, B*5306, B*5307 and confirmation of B*0809 and B*5606."
      Anholts J.D.H. , Kemps-Mols B. , Verduijn W. , Oudshoorn M. , Schreuder G.M.T.
      Tissue Antigens58:38-41(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELES B*53:06 AND B*53:07)
      tissue: Peripheral blood.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53."
      Smith K.J. , Reid S.W. , Harlos K. , McMichael A.J. , Stuart D.I. , Bell J.I. , Jones E.Y.
      Immunity4:215-228(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 25-302
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