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Index > Protein center > HLA-C(Gene name) > Human
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  • HLA-C (Gene name),
  • HLA class I histocompatibility antigen, Cw-3 alpha chain (Protein name ),  1C03_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HLA-C(HLAC);
    Protein name:
    HLA class I histocompatibility antigen, Cw-3 alpha chain;
    Alternative:
    MHC class I antigen Cw*3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein.
    Function:
    Involved in the presentation of foreign antigens to the immune system.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    366
    Sequence:
    50:
    MRVMAPRTLI | LLLSGALALT | ETWAGSHSMR | YFYTAVSRPG | RGEPHFIAVG | 
    100:
    YVDDTQFVRF | DSDAASPRGE | PRAPWVEQEG | PEYWDRETQK | YKRQAQTDRV | 
    150:
    SLRNLRGYYN | QSEAGSHIIQ | RMYGCDVGPD | GRLLRGYDQY | AYDGKDYIAL | 
    200:
    NEDLRSWTAA | DTAAQITQRK | WEAAREAEQL | RAYLEGLCVE | WLRRYLKNGK | 
    250:
    ETLQRAEHPK | THVTHHPVSD | HEATLRCWAL | GFYPAEITLT | WQWDGEDQTQ | 
    300:
    DTELVETRPA | GDGTFQKWAA | VVVPSGEEQR | YTCHVQHEGL | PEPLTLRWEP | 
    350:
    SSQPTIPIVG | IVAGLAVLAV | LAVLGAVVAV | VMCRRKSSGG | KGGSCSQAAS | 
    366:
    SNSAQGSDES | LIACKA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    SMR:
    Pfam:
    UniGene:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    ELISA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    CLIA Kit for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Polyclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Monoclonal Antibody for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain
    Protein for Human HLA class I histocompatibility antigen, Cw-3 alpha chain

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    Linearity
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    References
    1. 1.
      "Complete nucleotide sequence of a gene encoding a functional human class I histocompatibility antigen (HLA-CW3)."
      Sodoyer R. , Damotte M. , Delovitch T.L. , Trucy J. , Jordan B.R. , Strachan T.
      EMBO J.3:879-885(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE CW*03:04)
    2. 2.
      "The molecular basis for reactivity of anti-Cw1 and anti-Cw3 alloantisera with HLA-B46 haplotypes."
      Zemmour J. , Gumperz J.E. , Hildebrand W.H. , Ward F.E. , Marsh S.G.E. , Williams R.C. , Parham P.
      Tissue Antigens39:249-257(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE CW*03:02)
    3. 3.
      Domena J.D.
      Submitted (1994-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELES CW*03:03 AND CW*03:04)
    4. 4.
      "DNA typing of HLA-C locus alleles in Japanese."
      Wang H. , Tokunaga K. , Kuwata S.
      Submitted (1995-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ALLELE CW*03:03)
      tissue: Peripheral blood.
    5. 5.
      "Correction of the HLA-Cw3 genomic sequence tentatively identifies it as HLA-Cw*0304."
      Zarling A.L. , Smith K.D. , Lutz C.T. , Lee D.R.
      Immunogenetics44:82-83(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-206 (ALLELE CW*03:04)
    6. 6.
      "Sequencing based typing for HLA-C. Identification of three new alleles: Cw*0307, Cw*0502 and Cw*0504."
      Santos S. , Vicario J.L. , Garcia-Sanchez F. , Aviles M.J. , Balas A.
      Tissue Antigens58:34-37(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 26-206 (ALLELE CW*03:07)
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-206 (ALLELES CW*03:05; CW*03:06; CW*03:08 AND CW*03:09)
    8. 8.
      "Sequence of two new HLA-Cw alleles: HLA-Cw*0313 and HLA-Cw*1208."
      Cox S.T. , Ogilvie H. , Bohan E.M. , Holman R. , Prentice H.G. , Potter M. , Madrigal J.A. , Little A.-M.
      Tissue Antigens59:49-51(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE CW*03:13)
    9. 9.
      "Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand."
      Boyington J.C. , Motyka S.A. , Schuck P. , Brooks A.G. , Sun P.D.
      Nature405:537-543(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 25-302 IN COMPLEX WITH KIR2DL2;DISULFIDE BONDS
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