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Index > Protein center > Htr1b(Gene name) > Mouse
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  • Htr1b (Gene name),
  • 5-hydroxytryptamine receptor 1B (Protein name ),  5HT1B_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Htr1b(5ht1b);
    Protein name:
    5-hydroxytryptamine receptor 1B(5-HT-1B;5-HT1B);
    Alternative:
    Serotonin receptor 1B;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    386
    Sequence:
    50:
    MEEQGIQCAP | PPPAASQTGV | PLTNLSHNCS | ADGYIYQDSI | ALPWKVLLVA | 
    100:
    LLALITLATT | LSNAFVIATV | YRTRKLHTPA | NYLIASLAVT | DLLVSILVMP | 
    150:
    ISTMYTVTGR | WTLGQVVCDF | WLSSDITCCT | ASIMHLCVIA | LDRYWAITDA | 
    200:
    VEYSAKRTPK | RAAIMIVLVW | VFSISISLPP | FFWRQAKAEE | EMLDCFVNTD | 
    250:
    HVLYTVYSTV | GAFYLPTLLL | IALYGRIYVE | ARSRILKQTP | NKTGKRLTRA | 
    300:
    QLITDSPGST | SSVTSINSRA | PDVPSESGSP | VYVNQVKVRV | SDALLEKKKL | 
    350:
    MAARERKATK | TLGIILGAFI | VCWLPFFIIS | LVMPICKDAC | WFHMAIFDFF | 
    386:
    NWLGYLNSLI | NPIIYTMSNE | DFKQAFHKLI | RFKCAG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse 5-HT-1B
    MSDS:
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    ELISA Kit for Mouse 5-HT-1B
    Cat.:
    E10279h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse 5-HT-1B
    MSDS:
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    ELISA Kit for Mouse 5-HT-1B
    Cat.:
    E10279m
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    ELISA Kit for Mouse 5-HT-1B
    Cat.:
    E10279r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse 5-HT-1B
    MSDS:
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    CLIA Kit for Mouse 5-HT-1B
    MSDS:
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    CLIA Kit for Mouse 5-HT-1B
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse 5-HT-1B
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse 5-HT-1B
    Cat.:
    U10279m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse 5-HT-1B
    Cat.:
    U10279r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse 5-HT-1B
    Cat.:
    U10279h
    Price:
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    MSDS:
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    Packing:
    96T
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    Polyclonal Antibody for Mouse 5-HT-1B
    Polyclonal Antibody for Mouse 5-HT-1B
    Polyclonal Antibody for Mouse 5-HT-1B
    Polyclonal Antibody for Mouse 5-HT-1B
    Polyclonal Antibody for Mouse 5-HT-1B
    Polyclonal Antibody for Mouse 5-HT-1B
    Cat.:
    P10279Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse 5-HT-1B
    Monoclonal Antibody for Mouse 5-HT-1B
    Monoclonal Antibody for Mouse 5-HT-1B
    Monoclonal Antibody for Mouse 5-HT-1B
    Monoclonal Antibody for Mouse 5-HT-1B
    Monoclonal Antibody for Mouse 5-HT-1B
    Protein for Mouse 5-HT-1B
    Protein for Mouse 5-HT-1B
    Protein for Mouse 5-HT-1B
    Protein for Mouse 5-HT-1B
    Protein for Mouse 5-HT-1B
    Protein for Mouse 5-HT-1B

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    References
    1. 1.
      "Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers."
      Maroteaux L. , Saudou F. , Amlaiky N. , Boschert U. , Plassat J.-L. , Hen R.
      Proc. Natl. Acad. Sci. U.S.A.89:3020-3024(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    2. 2.
      "Enhanced aggressive behavior in mice lacking 5-HT1B receptor."
      Saudou F. , Amara D.A. , Dierich A. , LeMeur M. , Ramboz S. , Segu L. , Buhot M.C. , Hen R.
      Science265:1875-1878(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    3. 3.
      "Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice."
      Pineyro G. , Castanon N. , Hen R. , Blier P.
      NeuroReport7:353-359(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    4. 4.
      "Regulation of serotonin release in the frontal cortex and ventral hippocampus of homozygous mice lacking 5-HT1B receptors: in vivo microdialysis studies."
      Trillat A.C. , Malagie I. , Scearce K. , Pons D. , Anmella M.C. , Jacquot C. , Hen R. , Gardier A.M.
      J. Neurochem.69:2019-2025(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    5. 5.
      "5-HT1B receptors modulate release of [3H]dopamine from rat striatal synaptosomes: further evidence using 5-HT moduline, polyclonal 5-HT1B receptor antibodies and 5-HT1B receptor knock-out mice."
      Sarhan H. , Grimaldi B. , Hen R. , Fillion G.
      Naunyn Schmiedebergs Arch. Pharmacol.361:12-18(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    6. 6.
      "Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT1B-receptor knockout mice."
      Rutz S. , Riegert C. , Rothmaier A.K. , Buhot M.C. , Cassel J.C. , Jackisch R.
      Brain Res. Bull.70:81-93(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
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