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Index > Protein center > Serpina1b(Gene name) > Mouse
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  • Serpina1b (Gene name),
  • Alpha-1-antitrypsin 1-2 (Protein name ),  A1AT2_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Serpina1b(Aat2;Dom2;Spi1-2);
    Protein name:
    Alpha-1-antitrypsin 1-2(AAT);
    Alternative:
    Alpha-1-antiproteinase;Alpha-1 protease inhibitor 2;Serine protease inhibitor A1b(Serpin A1b);Serine protease inhibitor 1-2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    413
    Sequence:
    50:
    MTPSISWGLL | LLAGLCCMVP | SFLAEDVQET | DTSQKDQSPA | SHEIATNLGD | 
    100:
    FAISLYRELV | HQSNTSNIFF | SPVSIATAFA | MLSLGSKGDT | HTQILEGLQF | 
    150:
    NLTQTSEADI | HKSFQHLLQT | LNRPDSELQL | STGNGLFVNN | DLKLVEKFLE | 
    200:
    EAKNHYQAEV | FSVNFAESEE | AKKVINDFVE | KGTQGKIVEA | VKELDQDTVF | 
    250:
    ALANYILFKG | KWKKPFDPEN | TEEAEFHVDK | STTVKVPMMM | LSGMLDVHHC | 
    300:
    SILSSWVLLM | DYAGNASAVF | LLPEDGKMQH | LEQTLNKELI | SKILLNRRRR | 
    350:
    LVQIHIPRLS | ISGDYNLKTL | MSPLGITRIF | NNGADLSGIT | EENAPLKLSK | 
    400:
    AVHKAVLTID | ETGTEAAAAT | VFEAVPMSMP | PILRFDHPFL | FIIFEEHTQS | 
    413:
    PIFVGKVVDP | THK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse AAT
    CLIA Kit for Mouse AAT
    Polyclonal Antibody for Mouse AAT
    Monoclonal Antibody for Mouse AAT
    Protein for Mouse AAT

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Complete cDNA sequence and chromosomal localization of mouse alpha 1-antitrypsin."
      Sifers R.N. , Ledley F.D. , Reed-Fourquet L. , Ledbetter D.H. , Ledbetter S.A. , Woo S.L.C.
      Genomics6:100-104(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure."
      Barbour K.W. , Wei F. , Brannan C. , Flotte T.R. , Baumann H. , Berger F.G.
      Genomics80:515-522(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
    4. 4.
      "Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence."
      Borriello F. , Krauter K.S.
      Proc. Natl. Acad. Sci. U.S.A.88:9417-9421(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 12-413
      strain: C57BL/6.
      tissue: Liver.
    5. 5.
      "The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins."
      Paterson T. , Moore S.
      Biochem. Biophys. Res. Commun.219:64-69(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    6. 6.
      "Functional diversification during evolution of the murine alpha(1)-proteinase inhibitor family: role of the hypervariable reactive center loop."
      Barbour K.W. , Goodwin R.L. , Guillonneau F. , Wang Y. , Baumann H. , Berger F.G.
      Mol. Biol. Evol.19:718-727(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;REGION RCL
    7. 7.
      "A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins."
      Forsyth S. , Horvath A. , Coughlin P.
      Genomics81:336-345(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE FAMILY;NOMENCLATURE
    8. 8.
      "Proteome-wide characterization of N-glycosylation events by diagonal chromatography."
      Ghesquiere B. , Van Damme J. , Martens L. , Vandekerckhove J. , Gevaert K.
      J. Proteome Res.5:2438-2447(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-101 AND ASN-265
      strain: C57BL/6.
      tissue: Plasma.
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