Protein name:
Alpha-aminoadipic semialdehyde synthase, mitochondrial ;
Alternative:
LKR/SDH ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-oxoglutarate reductase and saccharopine dehydrogenase activity, respectively.
Subcellular Location:
Mitochondrion
Protein Attributes:
50:
MLRAQRPRLA | RLRACLSRGL | HHKPVMALRR | EDVNAWERRA | PLAPKHIKGI |
100:
TKLGYKVLIQ | PSNRRAIHDK | EYVRAGGILQ | EDITEACLIL | GVKRPPEEKL |
150:
MSKKTYAFFS | HTIKAQEANM | NLLDEVLKQE | IRLIDYEKMV | DHRGSRIVAF |
200:
GQWAGVAGMI | NILHGMGLRL | LALGHHTPFM | HLGMAHNYRN | SSQAVQAVRD |
250:
AGYEISLGLM | PKSIGPLTFV | FTGTGNVSKG | AQEVFNELPC | EYVEPHELRE |
300:
VSKTGDLRKV | YGTVLSRHHH | LVRKTDGVYD | PVEYEKYPER | YTSRFNTDIA |
350:
PYTTCLINGI | YWEQNTPRLL | TRQDAQSLLV | PVKSSVVPVE | GCPELPHKLV |
400:
AICDISADTG | GSIDFMTECT | TIERPFCMYD | ADQQIIHDSV | EGSGILMCSI |
450:
DNLPAQLPIE | ATEYFGDMLY | PYVEEMLLSD | ASQPLESQNF | SPVVRDAVIT |
500:
SNGLLTDKYK | YIQKLRESRE | RIQFLSMSTK | KKVLVLGSGY | VSGPVLEYLS |
550:
RDNNIEITLG | SDMTNQMQQL | SKKYNINPVS | LTVGKQEAKL | QSLVESQDLV |
600:
ISLLPYVLHP | VVAKACIESR | VNMVTASYIT | PAMKELEKSV | DDAGITVIGE |
650:
LGLDPGLDHM | LAMETIDTAK | ELGATVESYV | SYCGGLPAPE | HSDNPLRYKF |
700:
SWSPVGVLMN | IMQPASYLLN | GKVVNVTGGV | SFLNSVTPMD | YFPGLNLEGY |
750:
PNRDSIKYAE | IYGISSAHTL | LRGTLRYKGY | SKALNGFVKL | GLINREAYPA |
800:
LRPEANPLTW | KQLLCDLVGI | SRSSPCEKLK | EVVFTKLGGD | NTQLEAAEWL |
850:
GLLGDEQVPQ | AESIVDAFSK | HLVSKLSYGP | EEKDMIVMRD | SFGIRHPSGH |
900:
LENKTIDLVV | YGDFNGFSAM | AKTVGLPTAM | AAKMLLDGEI | EAKGLMGPFT |
926:
KEIYGPILER | IKAEGIVFNT | QSTIKL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Bovine
Human
ELISA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
ELISA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
ELISA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
ELISA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
CLIA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
CLIA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
CLIA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
CLIA Kit for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Polyclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Polyclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Polyclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Polyclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Monoclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Monoclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Monoclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Monoclonal Antibody for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Protein for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Protein for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Protein for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
Protein for Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6J X CBA/J .
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary tumor .
3.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
,
Chen Y.
,
Tishkoff D.X.
,
Peng C.
,
Tan M.
,
Dai L.
,
Xie Z.
,
Zhang Y.
,
Zwaans B.M.
,
Skinner M.E.
,
Lombard D.B.
,
Zhao Y.
Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-93; LYS-138; LYS-274; LYS-286; LYS-333; LYS-458; LYS-523; LYS-535; LYS-584; LYS-732 AND LYS-761;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
4.
"Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
Rardin M.J.
,
Newman J.C.
,
Held J.M.
,
Cusack M.P.
,
Sorensen D.J.
,
Li B.
,
Schilling B.
,
Mooney S.D.
,
Kahn C.R.
,
Verdin E.
,
Gibson B.W.
Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-48; LYS-52; LYS-56; LYS-93; LYS-128; LYS-138; LYS-286; LYS-458; LYS-523; LYS-535; LYS-584; LYS-707; LYS-739; LYS-761; LYS-778 AND LYS-780;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .