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Index > Protein center > GOT2(Gene name) > Chicken
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  • GOT2 (Gene name),
  • Aspartate aminotransferase, mitochondrial (Protein name ),  AATM_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GOT2;
    Protein name:
    Aspartate aminotransferase, mitochondrial(mAspAT);
    Alternative:
    Transaminase A;Glutamate oxaloacetate transaminase 2;Kynurenine--oxoglutarate transaminase 4;Kynurenine aminotransferase IV;Transaminase A;Kynurenine--oxoglutarate transaminase IV;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. May facilitate cellular uptake of long-chain free fatty acids.
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    423
    Sequence:
    50:
    MALLQSRLLL | SAPRRAAATA | RASSWWSHVE | MGPPDPILGV | TEAFKRDTNS | 
    100:
    KKMNLGVGAY | RDDNGKSYVL | NCVRKAEAMI | AAKKMDKEYL | PIAGLADFTR | 
    150:
    ASAELALGEN | SEAFKSGRYV | TVQGISGTGS | LRVGANFLQR | FFKFSRDVYL | 
    200:
    PKPSWGNHTP | IFRDAGLQLQ | AYRYYDPKTC | SLDFTGAMED | ISKIPEKSII | 
    250:
    LLHACAHNPT | GVDPRQEQWK | ELASVVKKRN | LLAYFDMAYQ | GFASGDINRD | 
    300:
    AWALRHFIEQ | GIDVVLSQSY | AKNMGLYGER | AGAFTVICRD | AEEAKRVESQ | 
    350:
    LKILIRPMYS | NPPMNGARIA | SLILNTPELR | KEWLVEVKGM | ADRIISMRTQ | 
    400:
    LVSNLKKEGS | SHNWQHITDQ | IGMFCFTGLK | PEQVERLTKE | FSIYMTKDGR | 
    423:
    ISVAGVASSN | VGYLAHAIHQ | VTK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken mAspAT
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    E1612h
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    ELISA Kit for Chicken mAspAT
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    ELISA Kit for Chicken mAspAT
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    ELISA Kit for Chicken mAspAT
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    E1612r
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    ELISA Kit for Chicken mAspAT
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    ELISA Kit for Chicken mAspAT
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    E1612b
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    96T
    ELISA Kit for Chicken mAspAT
    Cat.:
    E1612c
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    Packing:
    96T
    CLIA Kit for Chicken mAspAT
    Cat.:
    U1612c
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    CLIA Kit for Chicken mAspAT
    Cat.:
    U1612m
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    CLIA Kit for Chicken mAspAT
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    U1612r
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    CLIA Kit for Chicken mAspAT
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    CLIA Kit for Chicken mAspAT
    Cat.:
    U1612b
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    96T
    CLIA Kit for Chicken mAspAT
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    96T
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    CLIA Kit for Chicken mAspAT
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    U1612h
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    MSDS:
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    96T
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    Polyclonal Antibody for Chicken mAspAT
    Cat.:
    P1612Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken mAspAT
    Polyclonal Antibody for Chicken mAspAT
    Cat.:
    P1612Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken mAspAT
    Polyclonal Antibody for Chicken mAspAT
    Polyclonal Antibody for Chicken mAspAT
    Polyclonal Antibody for Chicken mAspAT
    Cat.:
    P1612Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Chicken mAspAT
    Monoclonal Antibody for Chicken mAspAT
    Monoclonal Antibody for Chicken mAspAT
    Monoclonal Antibody for Chicken mAspAT
    Monoclonal Antibody for Chicken mAspAT
    Monoclonal Antibody for Chicken mAspAT
    Monoclonal Antibody for Chicken mAspAT
    Protein for Chicken mAspAT
    Protein for Chicken mAspAT
    Protein for Chicken mAspAT
    Protein for Chicken mAspAT
    Protein for Chicken mAspAT
    Protein for Chicken mAspAT
    Protein for Chicken mAspAT

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    References
    1. 1.
      "The primary structure of the precursor of chicken mitochondrial aspartate aminotransferase. Cloning and sequence analysis of cDNA."
      Jaussi R. , Cotton B. , Juretic N. , Christen P. , Schumperli D.
      J. Biol. Chem.260:16060-16063(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The covalent structure of mitochondrial aspartate aminotransferase from chicken. Identification of segments of the polypeptide chain invariant specifically in the mitochondrial isoenzyme."
      Graf-Hausner U. , Wilson K.J. , Christen P.
      J. Biol. Chem.258:8813-8826(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 23-423
    3. 3.
      "Structure of the genes of two homologous intracellularly heterotopic isoenzymes. Cytosolic and mitochondrial aspartate aminotransferase of chicken."
      Juretic N. , Mattes U. , Ziak M. , Christen P. , Jaussi R.
      Eur. J. Biochem.192:119-126(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE STRUCTURE
      strain: White leghorn.
    4. 4.
      "X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase."
      McPhalen C.A. , Vincent M.G. , Jansonius J.N.
      J. Mol. Biol.225:495-517(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEXES WITH PYRIDOXAL PHOSPHATE;PYRIDOXAL PHOSPHATE AT LYS-272;COFACTOR;SUBUNIT
    5. 5.
      "Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase."
      Malashkevich V.N. , Toney M.D. , Jansonius J.N.
      Biochemistry32:13451-13462(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 23-423 IN COMPLEXES WITH PYRIDOXAL PHOSPHATE; L-ASPARTATE AND L-GLUTAMATE;COFACTOR;SUBUNIT
    6. 6.
      "Aspartate aminotransferase complexed with erythro-beta-hydroxyaspartate: crystallographic and spectroscopic identification of the carbinolamine intermediate."
      von Stosch A.G.
      Biochemistry35:15260-15268(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 23-423 IN COMPLEX WITH ERYTHRO-BETA-HYDROXYASPARTATE;COFACTOR
    7. 7.
      "Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase."
      Markovic-Housley Z. , Schirmer T. , Hohenester E. , Khomutov A.R. , Khomutov R.M. , Karpeisky M.Y. , Sandmeier E. , Christen P. , Jansonius J.N.
      Eur. J. Biochem.236:1025-1032(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 23-423 IN COMPLEXES WITH PYRIDOXAL PHOSPHATE AND SUBSTRATE ANALOGS;COFACTOR;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;SUBUNIT
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