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Index > Protein center > Got2(Gene name) > Mouse
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  • Got2 (Gene name),
  • Aspartate aminotransferase, mitochondrial (Protein name ),  AATM_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Got2(Got-2);
    Protein name:
    Aspartate aminotransferase, mitochondrial(mAspAT);
    Alternative:
    Glutamate oxaloacetate transaminase 2;Fatty acid-binding protein(FABP-1);Transaminase A;Plasma membrane-associated fatty acid-binding protein(FABPpm);Kynurenine--oxoglutarate transaminase IV;Kynurenine--oxoglutarate transaminase 4;Transaminase A;Plasma membrane-associated fatty acid-binding protein(FABPpm);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
    Subcellular Location:
    Mitochondrion matrix Cell membrane
    Protein Attributes:
    Sequence length:
    430
    Sequence:
    50:
    MALLHSSRIL | SGMAAAFHPG | LAAAASARAS | SWWTHVEMGP | PDPILGVTEA | 
    100:
    FKRDTNSKKM | NLGVGAYRDD | NGKPYVLPSV | RKAEAQIAAK | NLDKEYLPIG | 
    150:
    GLAEFCKASA | ELALGENNEV | LKSGRFVTVQ | TISGTGALRV | GASFLQRFFK | 
    200:
    FSRDVFLPKP | SWGNHTPIFR | DAGMQLQGYR | YYDPKTCGFD | FSGALEDISK | 
    250:
    IPEQSVLLLH | ACAHNPTGVD | PRPEQWKEIA | SVVKKKNLFA | FFDMAYQGFA | 
    300:
    SGDGDKDAWA | VRHFIEQGIN | VCLCQSYAKN | MGLYGERVGA | FTVVCKDAEE | 
    350:
    AKRVESQLKI | LIRPLYSNPP | LNGARIAATI | LTSPDLRKQW | LQEVKGMADR | 
    400:
    IISMRTQLVS | NLKKEGSSHN | WQHITDQIGM | FCFTGLKPEQ | VERLTKEFSV | 
    430:
    YMTKDGRISV | AGVTSGNVGY | LAHAIHQVTK | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse mAspAT
    Cat.:
    E1612h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse mAspAT
    Cat.:
    E1612p
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse mAspAT
    Cat.:
    E1612m
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse mAspAT
    Cat.:
    E1612r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse mAspAT
    MSDS:
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    ELISA Kit for Mouse mAspAT
    Cat.:
    E1612b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse mAspAT
    Cat.:
    E1612c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse mAspAT
    Cat.:
    U1612c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse mAspAT
    Cat.:
    U1612m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse mAspAT
    Cat.:
    U1612r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Mouse mAspAT
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse mAspAT
    Cat.:
    U1612b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse mAspAT
    Cat.:
    U1612p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse mAspAT
    Cat.:
    U1612h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Mouse mAspAT
    Cat.:
    P1612Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse mAspAT
    Polyclonal Antibody for Mouse mAspAT
    Cat.:
    P1612Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse mAspAT
    Polyclonal Antibody for Mouse mAspAT
    Polyclonal Antibody for Mouse mAspAT
    Polyclonal Antibody for Mouse mAspAT
    Cat.:
    P1612Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse mAspAT
    Monoclonal Antibody for Mouse mAspAT
    Monoclonal Antibody for Mouse mAspAT
    Monoclonal Antibody for Mouse mAspAT
    Monoclonal Antibody for Mouse mAspAT
    Monoclonal Antibody for Mouse mAspAT
    Monoclonal Antibody for Mouse mAspAT
    Protein for Mouse mAspAT
    Protein for Mouse mAspAT
    Protein for Mouse mAspAT
    Protein for Mouse mAspAT
    Protein for Mouse mAspAT
    Protein for Mouse mAspAT
    Protein for Mouse mAspAT

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and sequence analysis of mRNA for mouse aspartate aminotransferase isoenzymes."
      Obaru K. , Nomiyama H. , Shimada K. , Nagashima F. , Morino Y.
      J. Biol. Chem.261:16976-16983(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structural organization of the mouse mitochondrial aspartate aminotransferase gene."
      Tsuzuki T. , Obaru K. , Setoyama C. , Shimada K.
      J. Mol. Biol.198:21-31(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C3H/He.
      tissue: Liver.
    3. 3.
      "Mitochondrial aspartate aminotransferase: direction of a single protein with two distinct functions to two subcellular sites does not require alternative splicing of the mRNA."
      Bradbury M.W. , Berk P.D.
      Biochem. J.345:423-427(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
      strain: FVB.
      tissue: Liver.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: BALB/c.
      strain: C57BL/6J.
      strain: NOD.
      tissue: Bone marrow macrophage.
      tissue: Cecum.
      tissue: Dendritic cell.
      tissue: Melanocyte.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
      tissue: Eye.
    6. 6.
      Lubec G. , Kang S.U. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 60-81; 91-122; 126-139; 171-180; 186-200; 280-296; 310-345; 356-363 AND 397-404;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      strain: OF1.
      tissue: Brain.
      tissue: Hippocampus.
    7. 7.
      "Mitochondrial aspartate aminotransferase expressed on the surface of 3T3-L1 adipocytes mediates saturable fatty acid uptake."
      Zhou S.-L. , Stump D. , Kiang C.L. , Isola L.M. , Berk P.D.
      Proc. Soc. Exp. Biol. Med.208:263-270(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    8. 8.
      "Endogenously nitrated proteins in mouse brain: links to neurodegenerative disease."
      Sacksteder C.A. , Qian W.-J. , Knyushko T.V. , Wang H. , Chin M.H. , Lacan G. , Melega W.P. , Camp D.G. II , Smith R.D. , Smith D.J. , Squier T.C. , Bigelow D.J.
      Biochemistry45:8009-8022(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NITRATION [LARGE SCALE ANALYSIS] AT TYR-96;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    9. 9.
      "Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain."
      Guidetti P. , Amori L. , Sapko M.T. , Okuno E. , Schwarcz R.
      J. Neurochem.102:103-111(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;TISSUE SPECIFICITY
    10. 10.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-73; LYS-159 AND LYS-404;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-73; LYS-90; LYS-107; LYS-122; LYS-159; LYS-185; LYS-227; LYS-296; LYS-309; LYS-338; LYS-363; LYS-396 AND LYS-404;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
      tissue: Liver.
    11. 11.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-59; LYS-73; LYS-82; LYS-90; LYS-107; LYS-122; LYS-159; LYS-185; LYS-234; LYS-279; LYS-296; LYS-302; LYS-309; LYS-338; LYS-345; LYS-363; LYS-364; LYS-387; LYS-396 AND LYS-404;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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      Han Q. , Cai T. , Tagle D.A. , Li J.
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 30-430 IN COMPLEX WITH SYNTHETIC INHIBITOR;SUBUNIT
    13. 13.
      "Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV."
      Han Q. , Robinson H. , Cai T. , Tagle D.A. , Li J.
      Biosci. Rep.31:323-332(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 30-430 IN COMPLEX WITH L-KYNURENINE; OXALOACETATE AND PYRIDOXAL PHOSPHATE;CATALYTIC ACTIVITY;FUNCTION;SUBUNIT;COFACTOR
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