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Index > Protein center > Got2(Gene name) > Rat
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  • Got2 (Gene name),
  • Aspartate aminotransferase, mitochondrial (Protein name ),  AATM_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Got2(Maat);
    Protein name:
    Aspartate aminotransferase, mitochondrial(mAspAT);
    Alternative:
    Glutamate oxaloacetate transaminase 2;Fatty acid-binding protein(FABP-1);Transaminase A;Plasma membrane-associated fatty acid-binding protein(FABPpm);Kynurenine--oxoglutarate transaminase IV;Kynurenine--oxoglutarate transaminase 4;Transaminase A;Plasma membrane-associated fatty acid-binding protein(FABPpm);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
    Subcellular Location:
    Mitochondrion matrix Cell membrane Located in the mitochondria of liver, pancreas, spleen, heart, pituitary gland and submandibular gland cells. In kidney, located in the mitochondria, on the cell surface of regions with protrusions in distal tubules, on the apical cell surface of protrusions along the microvilli in cortical collecting ducts, in condensing vacuoles, on the cell surface at cell boundaries of adjoining kidney cells and on the cell surface of endothelial cells lining capillaries in the glomerulus. Also located at the cell surface of endothelial cells lining arterioles and on the cell surface of lymphocytes.
    Protein Attributes:
    Sequence length:
    430
    Sequence:
    50:
    MALLHSGRVL | SGMAAAFHPG | LAAAASARAS | SWWTHVEMGP | PDPILGVTEA | 
    100:
    FKRDTNSKKM | NLGVGAYRDD | NGKPYVLPSV | RKAEAQIAGK | NLDKEYLPIG | 
    150:
    GLADFCKASA | ELALGENSEV | LKSGRFVTVQ | TISGTGALRV | GASFLQRFFK | 
    200:
    FSRDVFLPKP | SWGNHTPIFR | DAGMQLQGYR | YYDPKTCGFD | FSGALEDISK | 
    250:
    IPEQSVLLLH | ACAHNPTGVD | PRPEQWKEMA | AVVKKKNLFA | FFDMAYQGFA | 
    300:
    SGDGDKDAWA | VRHFIEQGIN | VCLCQSYAKN | MGLYGERVGA | FTVVCKDAEE | 
    350:
    AKRVESQLKI | LIRPLYSNPP | LNGARIAATI | LTSPDLRKQW | LQEVKGMADR | 
    400:
    IISMRTQLVS | NLKKEGSSHN | WQHITDQIGM | FCFTGLKPEQ | VERLTKEFSV | 
    430:
    YMTKDGRISV | AGVTSGNVGY | LAHAIHQVTK | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat mAspAT
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    E1612h
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    ELISA Kit for Rat mAspAT
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    E1612p
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    ELISA Kit for Rat mAspAT
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    ELISA Kit for Rat mAspAT
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    E1612r
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    ELISA Kit for Rat mAspAT
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    ELISA Kit for Rat mAspAT
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    E1612b
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    96T
    ELISA Kit for Rat mAspAT
    Cat.:
    E1612c
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    96T
    CLIA Kit for Rat mAspAT
    Cat.:
    U1612c
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    CLIA Kit for Rat mAspAT
    Cat.:
    U1612m
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    96T
    CLIA Kit for Rat mAspAT
    Cat.:
    U1612r
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    96T
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    CLIA Kit for Rat mAspAT
    MSDS:
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    CLIA Kit for Rat mAspAT
    Cat.:
    U1612b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat mAspAT
    Cat.:
    U1612p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Rat mAspAT
    Cat.:
    U1612h
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    MSDS:
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    Packing:
    96T
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    Polyclonal Antibody for Rat mAspAT
    Cat.:
    P1612Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat mAspAT
    Polyclonal Antibody for Rat mAspAT
    Cat.:
    P1612Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat mAspAT
    Polyclonal Antibody for Rat mAspAT
    Polyclonal Antibody for Rat mAspAT
    Polyclonal Antibody for Rat mAspAT
    Cat.:
    P1612Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat mAspAT
    Monoclonal Antibody for Rat mAspAT
    Monoclonal Antibody for Rat mAspAT
    Monoclonal Antibody for Rat mAspAT
    Monoclonal Antibody for Rat mAspAT
    Monoclonal Antibody for Rat mAspAT
    Monoclonal Antibody for Rat mAspAT
    Protein for Rat mAspAT
    Protein for Rat mAspAT
    Protein for Rat mAspAT
    Protein for Rat mAspAT
    Protein for Rat mAspAT
    Protein for Rat mAspAT
    Protein for Rat mAspAT

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    References
    1. 1.
      "Molecular cloning and in vivo expression of a precursor to rat mitochondrial aspartate aminotransferase."
      Mattingly J.R. Jr. , Rodriguez-Berrocal F.J. , Gordon J. , Iriarte A. , Martinez-Carrion M.
      Biochem. Biophys. Res. Commun.149:859-865(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
    3. 3.
      "Androgen modulation of multiple transcription start sites of the mitochondrial aspartate aminotransferase gene in rat prostate."
      Juang H.H. , Costello L.C. , Franklin R.B.
      J. Biol. Chem.270:12629-12634(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30
      strain: Wistar.
      tissue: Liver.
    4. 4.
      "Primary structure of mitochondrial glutamic oxaloacetic transaminase from rat liver: comparison with that of the pig heart isozyme."
      Huynh Q.K. , Sakakibara R. , Watanabe T. , Wada H.
      Biochem. Biophys. Res. Commun.97:474-479(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-430
      tissue: Liver.
    5. 5.
      "The complete amino acid sequence of mitochondrial glutamic oxaloacetic transaminase from rat liver."
      Huynh Q.K. , Sakakibara R. , Watanabe T. , Wada H.
      J. Biochem.90:863-875(1981) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-430
      tissue: Liver.
    6. 6.
      "Comparison of plasma membrane FABP and mitochondrial isoform of aspartate aminotransferase from rat liver."
      Stump D.D. , Zhou S.-L. , Berk P.D.
      Am. J. Physiol.265:G894-G902(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-64
      strain: Sprague-Dawley.
      tissue: Liver.
    7. 7.
      "Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain."
      Guidetti P. , Amori L. , Sapko M.T. , Okuno E. , Schwarcz R.
      J. Neurochem.102:103-111(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-42;CATALYTIC ACTIVITY;FUNCTION
    8. 8.
      Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Kang S.U.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 60-68; 91-122; 126-147; 171-180; 186-200; 280-296; 310-337; 356-363 AND 397-404;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Brain.
      tissue: Hippocampus.
      tissue: Spinal cord.
    9. 9.
      "Molecular cloning of rat mitochondrial glutamic oxaloacetic transaminase mRNA and regulation of its expression in regenerating liver."
      Horio Y. , Sakakibara R. , Tanaka T. , Taketoshi M. , Obaru K. , Shimada K. , Morino Y. , Wada H.
      Biochem. Biophys. Res. Commun.134:803-811(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 279-329
    10. 10.
      "Immunogold localization of mitochondrial aspartate aminotransferase in mitochondria and on the cell surface in normal rat tissues."
      Cechetto J.D. , Sadacharan S.K. , Berk P.D. , Gupta R.S.
      Histol. Histopathol.17:353-364(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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