Protein name:
ATP-binding cassette sub-family A member 7 ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Golgi apparatus membrane
Multi-pass membrane protein
Endosome membrane
Multi-pass membrane protein
Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney.
Protein Attributes:
50:
MAFCTQLMLL | LWKNYTYRRR | QPIQLVVELL | WPLFLFFILV | AVRHSHPPLE |
100:
HHECHFPNKP | LPSAGTVPWL | QGLVCNVNNS | CFQHPTPGEK | PGVLSNFKDS |
150:
LISRLLADAH | TVLGGHSTQD | MLAALGKLIP | VLRAVGSGAW | PQESNQPAKQ |
200:
GSVTELLEKI | LQRASLETVL | GQAQDSMRKF | SDATRTVAQE | LLTLPSLVEL |
250:
RALLRRPRGS | AGSLELISEA | LCSTKGPSSP | GGLSLNWYEA | NQINEFMGPE |
300:
LAPTLPDSSL | SPACSEFVGA | LDDHPVSRLL | WRRLKPLILG | KILFAPDTNF |
350:
TRKLMAQVNQ | TFEELALLRD | LHELWGVLGP | QIFNFMNDST | NVAMLQKLLD |
400:
VEGTGWQQQT | PKGQKQLEAI | RDFLDPSRGR | YNWQEAHADM | GRLAEILGQI |
450:
LECVSLDKLE | AVPSEEALVS | RALELLGERR | LWAGIVFLSP | EHPLDSSEPP |
500:
SPTTTGPGHL | RVKIRMDIDD | VTRTNKIRDK | FWDPGPSADP | LMDLRYVWGG |
550:
FVYLQDLLEQ | AAVRVLSGRD | SRAGLYLQQM | PHPCYVDDVF | LRVLSRSLPL |
600:
FLTLAWIYSV | ALTVKAVVRE | KETRLRETMR | AMGLSRAVLW | LGWFLSCLGP |
650:
FLVSAALLVL | VLKLGNILPY | SHPVVVFLFL | AAFAVATVAQ | SFLLSAFFSR |
700:
ANLAAACGGL | AYFALYLPYV | LCVAWRERLP | LGGLLAVSLL | SPVAFGFGCE |
750:
SLALLEEQGD | GAQWHNLGTG | PAEDVFSLAQ | VSAFLLLDAV | IYGLALWYLE |
800:
AVCPGQYGIP | EPWNFPFRRS | YWCGPGPPKS | SVLAPAPQDP | KVLVEEPPPG |
850:
LVPGVSIRGL | KKHFRGSPQP | ALRGLNLDFY | EGHITAFLGH | NGAGKTTTLS |
900:
ILSGLFPPSS | GSASILGHDV | QTNMAAIRPH | LGICPQYNVL | FDMLTVEEHV |
950:
WFYGRLKGVS | AAAIDSEQEH | LIRDVGLIPK | RDTQTRHLSG | GMQRKLSVAI |
1000:
AFVGGSRVVI | MDEPTAGVDP | ASRRGIWELL | LKYREGRTLI | LSTHHLDEAE |
1050:
LLGDRVAMVA | SGSLCCCGSP | LFLRRHLGCG | YYLTLVKSSQ | SLVTHDLKGD |
1100:
TEDPRREKKS | GSEGKTADTV | LTRDGPHRSS | QVPAPDAVPV | TPSAALILEL |
1150:
VQRHVPGAQL | VEELPHELVL | ALPYAGALDG | SFATVFQELD | QQLERLGLTG |
1200:
YGISDTNLEE | IFLKVVEEAH | AHGEGGDPRQ | QQHLLTATPQ | PHTGPEASVL |
1250:
ENGELAKLVL | DPQAPKGSAP | TTAQVQGWTL | TCQQLRALLH | KRFLLARRSR |
1300:
RGLFAQIVLP | ALFVGLALFF | TLIVPPFGQY | PPLQLSPAMY | GPQVSFFSED |
1350:
APADPNRMKL | LEALLGEAGL | QDPSVQGKGS | RGSECTHSLA | CYFTVPEVPP |
1400:
DVASILASGN | WTPDSPSPAC | QCSQPGARRL | LPDCPAGAGG | PPPPQAMAGF |
1450:
GEVVQNLTGR | NVSDFLVKTY | PSLVRRGLKT | KKWVDEVRYG | GFSLGGRDPD |
1500:
LPSGREVVRT | VAEMRALLSP | QPGNTLDRIL | NNLTQWALGL | DARNSLKIWF |
1550:
NNKGWHAMVA | FVNRANNGLL | RAFLPSGSVR | HAHSITTLNH | PLNLTKEQLS |
1600:
EATLIASSVD | VLVSICVVFA | MSFVPASFTL | VLIEERITRA | KHLQLVSGLP |
1650:
QTLYWLGNFL | WDMCNYLVAV | CIVVLIFLAF | QQKAYVAPEN | LPALLLLLLL |
1700:
YGWSITPLMY | PASFFFSVPS | TAYVVLTCIN | LFIGINSSMA | TFVLELLSDQ |
1750:
NLQEVSRILK | QVFLIFPHFC | LGRGLIDMVR | NQAMADAFER | LGDKQFQSPL |
1800:
RWDIIGKNLL | AMVAQGPLFL | LITLLLQHRN | RLLPQPKSRL | PPPLGEEDED |
1850:
VVRERERVTK | GATQGDVLVL | RDLTKVYRGQ | RSPAVDHLCL | GIPPGECFGL |
1900:
LGVNGAGKTS | TFRMVTGDTL | PSSGEAVLAG | HNVAQEPSAA | HRSMGYCPQS |
1950:
DAIFDLLTGR | EHLELFARLR | GVPEAQVAQT | ALSGLVRLGL | PSYADRPAGT |
2000:
YSGGNKRKLA | TALALVGDPA | VVFLDEPTTG | MDPSARRFLW | NNLLSVVREG |
2050:
RSVVLTSHSM | EECEALCTRL | AIMVNGRFRC | LGSAQHLKSR | FGAGHTLTLR |
2100:
VPPDQPEPAI | AFIVTTFPDA | ELREVHGSRL | RFQLPPGGGC | TLARVFRELA |
2150:
AQGKAHGVED | FSVSQTTLEE | VFLYFSKDQG | EEEEGSGQET | ETREVSTPGL |
2170:
QHPKRVSRFL | EDPSSVETVI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat ATP-binding cassette sub-family A member 7
ELISA Kit for Rat ATP-binding cassette sub-family A member 7
ELISA Kit for Rat ATP-binding cassette sub-family A member 7
CLIA Kit for Rat ATP-binding cassette sub-family A member 7
CLIA Kit for Rat ATP-binding cassette sub-family A member 7
CLIA Kit for Rat ATP-binding cassette sub-family A member 7
Polyclonal Antibody for Rat ATP-binding cassette sub-family A member 7
Polyclonal Antibody for Rat ATP-binding cassette sub-family A member 7
Polyclonal Antibody for Rat ATP-binding cassette sub-family A member 7
Monoclonal Antibody for Rat ATP-binding cassette sub-family A member 7
Monoclonal Antibody for Rat ATP-binding cassette sub-family A member 7
Monoclonal Antibody for Rat ATP-binding cassette sub-family A member 7
Protein for Rat ATP-binding cassette sub-family A member 7
Protein for Rat ATP-binding cassette sub-family A member 7
Protein for Rat ATP-binding cassette sub-family A member 7
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain :
Wistar .
tissue :
Platelet .