ABCB6 ELISA Kit for Human(Homo sapiens) | EIAab.comABCB6 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > ABCB6(Gene name) > Human

ABCB6 (Gene name),

ATP-binding cassette sub-family B member 6, mitochondrial (Protein name ), ABCB6_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

ABCB6(MTABC3;PRP;UMAT);

Protein name:

ATP-binding cassette sub-family B member 6, mitochondrial;

Alternative:

P-glycoprotein-related protein;Mitochondrial ABC transporter 3(Mt-ABC transporter 3);Ubiquitously-expressed mammalian ABC half transporter;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer.

Function:

Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.

Subcellular Location:

Mitochondrion outer membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

842

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

842:

CIVERGRHEA | LLSRGGVYAD | MWQLQQGQEE | TSEDTKPQTM | ER

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Q9NP58

MIM:

605452

KEGG:

hsa:10058

Pfam:

PF00664

UniGene:

Hs.107911

String:

Q9NP58

STRING:

9606.ENSP00000265316

MIM:

111600

Uniprot:

Q9NP58

FOR

ELISA Kit for Human ATP-binding cassette sub-family B member 6, mitochondrial

CLIA Kit for Human ATP-binding cassette sub-family B member 6, mitochondrial

Polyclonal Antibody for Human ATP-binding cassette sub-family B member 6, mitochondrial

Monoclonal Antibody for Human ATP-binding cassette sub-family B member 6, mitochondrial

Protein for Human ATP-binding cassette sub-family B member 6, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis."
Mitsuhashi N. , Miki T. , Senbongi H. , Yokoi N. , Yano H. , Miyazaki M. , Nakajima N. , Iwanaga T. , Yokoyama Y. , Shibata T. , Seino S.
J. Biol. Chem.275:17536-17540(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
2.

"Isolation of a genomic clone containing the promoter region of the human ATP binding cassette (ABC) transporter, ABCB6."
Emadi-Konjin H.-P. , Zhang H. , Anandan V. , Sun D. , Schuetz J.D. , Furuya K.N.
Biochim. Biophys. Acta1574:117-130(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-229
tissue: Colon.
tissue: Liver.
3.

"Subcellular localization of the ABC transporter umat."
Hirsch-Ernst K.I. , Schaefer A. , Ernst B.-P. , Schmitz-Salue C. , Awuah D. , Kahl G.F.
Submitted (2000-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 112-842 (ISOFORM 1)
tissue: Hepatoma.
tissue: Neuroepithelium.
5.

Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
Submitted (2005-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
7.

Yu W. , Gibbs R.A.
Submitted (1998-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 332-842 (ISOFORM 1)
tissue: Brain.
8.

"Identification of a mammalian mitochondrial porphyrin transporter."
Krishnamurthy P.C. , Du G. , Fukuda Y. , Sun D. , Sampath J. , Mercer K.E. , Wang J. , Sosa-Pineda B. , Murti K.G. , Schuetz J.D.
Nature443:586-589(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE;INDUCTION BY CELLULAR PORPHYRINS;SUBUNIT;SUBCELLULAR LOCATION;INTERACTION WITH HEMIN
9.

"Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane."
Paterson J.K. , Shukla S. , Black C.M. , Tachiwada T. , Garfield S. , Wincovitch S. , Ernst D.N. , Agadir A. , Li X. , Ambudkar S.V. , Szakacs G. , Akiyama S. , Gottesman M.M.
Biochemistry46:9443-9452(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
10.

"Human ABC transporter isoform B6 (ABCB6) localizes primarily in the Golgi apparatus."
Tsuchida M. , Emi Y. , Kida Y. , Sakaguchi M.
Biochem. Biophys. Res. Commun.369:369-375(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
11.

"ABCB6 mutations cause ocular coloboma."
Wang L. , He F. , Bu J. , Liu X. , Du W. , Dong J. , Cooney J.D. , Dubey S.K. , Shi Y. , Gong B. , Li J. , McBride P.F. , Jia Y. , Lu F. , Soltis K.A. , Lin Y. , Namburi P. , Liang C. , more...
Am. J. Hum. Genet.90:40-48(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;VARIANTS MCOPCB7 THR-57 AND VAL-811;CHARACTERIZATION OF VARIANTS MCOPCB7 THR-57 AND VAL-811
12.

"ABCB6 is dispensable for erythropoiesis and specifies the new blood group system Langereis."
Helias V. , Saison C. , Ballif B.A. , Peyrard T. , Takahashi J. , Takahashi H. , Tanaka M. , Deybach J.C. , Puy H. , Le Gall M. , Sureau C. , Pham B.N. , Le Pennec P.Y. , Tani Y. , Cartron J.P. , Arnaud L.
Nat. Genet.44:170-173(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LANGEREIS BLOOD GROUP SYSTEM
13.

"Missense mutations in the ABCB6 transporter cause dominant familial pseudohyperkalemia."
Andolfo I. , Alper S.L. , Delaunay J. , Auriemma C. , Russo R. , Asci R. , Esposito M.R. , Sharma A.K. , Shmukler B.E. , Brugnara C. , De Franceschi L. , Iolascon A.
Am. J. Hematol.88:66-72(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INDUCTION;VARIANTS GLN-375 AND TRP-375;INVOLVEMENT IN FAMILIAL PSEUDOHYPERKALEMIA
14.

"Heteronuclear multidimensional NMR and homology modelling studies of the C-terminal nucleotide-binding domain of the human mitochondrial ABC transporter ABCB6."
Kurashima-Ito K. , Ikeya T. , Senbongi H. , Tochio H. , Mikawa T. , Shibata T. , Ito Y.
J. Biomol. NMR35:53-71(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 558-842 IN COMPLEX WITH ADP
15.

"Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides."
Haffke M. , Menzel A. , Carius Y. , Jahn D. , Heinz D.W.
Acta Crystallogr. D66:979-987(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 558-842 IN COMPLEXES WITH ADP; ATP AND PHOSPHATE
16.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] GLY-69
17.

"Mutations in ABCB6 cause dyschromatosis universalis hereditaria."
Zhang C. , Li D. , Zhang J. , Chen X. , Huang M. , Archacki S. , Tian Y. , Ren W. , Mei A. , Zhang Q. , Fang M. , Su Z. , Yin Y. , Liu D. , Chen Y. , Cui X. , Li C. , Yang H. , more...
J. Invest. Dermatol.133:2221-2228(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DUH3 GLY-170; PRO-356 AND GLU-579;CHARACTERIZATION OF VARIANTS DUH3 GLY-170; PRO-356 AND GLU-579
18.

"Novel mutations of ABCB6 associated with autosomal dominant dyschromatosis universalis hereditaria."
Cui Y.X. , Xia X.Y. , Zhou Y. , Gao L. , Shang X.J. , Ni T. , Wang W.P. , Fan X.B. , Yin H.L. , Jiang S.J. , Yao B. , Hu Y.A. , Wang G. , Li X.J.
PLoS ONE8:E79808-E79808(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DUH3 LYS-555
19.

"Genome-wide linkage, exome sequencing and functional analyses identify ABCB6 as the pathogenic gene of dyschromatosis universalis hereditaria."
Liu H. , Li Y. , Hung K.K. , Wang N. , Wang C. , Chen X. , Sheng D. , Fu X. , See K. , Foo J.N. , Low H. , Liany H. , Irwan I.D. , Liu J. , Yang B. , Chen M. , Yu Y. , Yu G. , more...
PLoS ONE9:E87250-E87250(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DUH3 VAL-453

Product Feedback Wall

* Email:
*Comments: