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Index > Protein center > Abcc8(Gene name) > Rat
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  • Abcc8 (Gene name),
  • ATP-binding cassette sub-family C member 8 (Protein name ),  ABCC8_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Abcc8(Sur;Sur1);
    Protein name:
    ATP-binding cassette sub-family C member 8;
    Alternative:
    Sulfonylurea receptor 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with KCNJ11.
    Function:
    Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1582
    Sequence:
    50:
    MPLAFCGTEN | HSAAYRVDQG | VLNNGCFVDA | LNVVPHVFLL | FITFPILFIG | 
    100:
    WGSQSSKVHI | HHSTWLHFPG | HNLRWILTFI | LLFVLVCEIA | EGILSDGVTE | 
    150:
    SRHLHLYMPA | GMAFMAAITS | VVYYHNIETS | NFPKLLIALL | IYWTLAFITK | 
    200:
    TIKFVKFYDH | AIGFSQLRFC | LTGLLVILYG | MLLLVEVNVI | RVRRYVFFKT | 
    250:
    PREVKPPEDL | QDLGVRFLQP | FVNLLSKGTY | WWMNAFIKTA | HKKPIDLRAI | 
    300:
    GKLPIAMRAL | TNYQRLCLAF | DAQARKDTQS | QQGARAIWRA | LCHAFGRRLV | 
    350:
    LSSTFRILAD | LLGFAGPLCI | FGIVDHLGKE | NHVFQPKTQF | LGVYFVSSQE | 
    400:
    FLGNAYVLAV | LLFLALLLQR | TFLQASYYVA | IETGINLRGA | IQTKIYNKIM | 
    450:
    HLSTSNLSMG | EMTAGQICNL | VAIDTNQLMW | FFFLCPNLWA | MPVQIIVGVI | 
    500:
    LLYYILGVSA | LIGAAVIILL | APVQYFVATK | LSQAQRSTLE | YSNERLKQTN | 
    550:
    EMLRGIKLLK | LYAWENIFCS | RVEKTRRKEM | TSLRAFAVYT | SISIFMNTAI | 
    600:
    PIAAVLITFV | GHVSFFKESD | FSPSVAFASL | SLFHILVTPL | FLLSSVVRST | 
    650:
    VKALVSVQKL | SEFLSSAEIR | EEQCAPREPA | PQGQAGKYQA | VPLKVVNRKR | 
    700:
    PAREEVRDLL | GPLQRLTPST | DGDADNFCVQ | IIGGFFTWTP | DGIPTLSNIT | 
    750:
    IRIPRGQLTM | IVGQVGCGKS | SLLLATLGEM | QKVSGAVFWN | SSLPDSEGED | 
    800:
    PSNPERETAA | DSDARSRGPV | AYASQKPWLL | NATVEENITF | ESPFNKQRYK | 
    850:
    MVIEACSLQP | DIDILPHGDQ | TQIGERGINL | SGGQRQRISV | ARALYQHTNV | 
    900:
    VFLDDPFSAL | DVHLSDHLMQ | AGILELLRDD | KRTVVLVTHK | LQYLPHADWI | 
    950:
    IAMKDGTIQR | EGTLKDFQRS | ECQLFEHWKT | LMNRQDQELE | KETVMERKAP | 
    1000:
    EPSQGLPRAM | SSRDGLLLDE | DEEEEEAAES | EEDDNLSSVL | HQRAKIPWRA | 
    1050:
    CTKYLSSAGI | LLLSLLVFSQ | LLKHMVLVAI | DYWLAKWTDS | ALVLSPAARN | 
    1100:
    CSLSQECALD | QSVYAMVFTV | LCSLGIALCL | VTSVTVEWTG | LKVAKRLHRS | 
    1150:
    LLNRIILAPM | RFFETTPLGS | ILNRFSSDCN | TIDQHIPSTL | ECLSRSTLLC | 
    1200:
    VSALAVISYV | TPVFLVALLP | LAVVCYFIQK | YFRVASRDLQ | QLDDTTQLPL | 
    1250:
    LSHFAETVEG | LTTIRAFRYE | ARFQQKLLEY | TDSNNIASLF | LTAANRWLEV | 
    1300:
    RMEYIGACVV | LIAAATSISN | SLHRELSAGL | VGLGLTYALM | VSNYLNWMVR | 
    1350:
    NLADMEIQLG | AVKRIHTLLK | TEAESYEGLL | APSLIPKNWP | DQGKIQIQNL | 
    1400:
    SVRYDSSLKP | VLKHVNALIS | PGQKIGICGR | TGSGKSSFSL | AFFRMVDMFE | 
    1450:
    GRIIIDGIDI | AKLPLHTLRS | RLSIILQDPV | LFSGTIRFNL | DPEKKCSDST | 
    1500:
    LWEALEIAQL | KLVVKALPGG | LDAIITEGGE | NFSQGQRQLF | CLARAFVRKT | 
    1550:
    SIFIMDEATA | SIDMATENIL | QKVVMTAFAD | RTVVTIAHRV | HTILSADLVM | 
    1582:
    VLKRGAILEF | DKPEKLLSQK | DSVFASFVRA | DK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat ATP-binding cassette sub-family C member 8
    ELISA Kit for Rat ATP-binding cassette sub-family C member 8
    CLIA Kit for Rat ATP-binding cassette sub-family C member 8
    CLIA Kit for Rat ATP-binding cassette sub-family C member 8
    Polyclonal Antibody for Rat ATP-binding cassette sub-family C member 8
    Polyclonal Antibody for Rat ATP-binding cassette sub-family C member 8
    Monoclonal Antibody for Rat ATP-binding cassette sub-family C member 8
    Monoclonal Antibody for Rat ATP-binding cassette sub-family C member 8
    Protein for Rat ATP-binding cassette sub-family C member 8
    Protein for Rat ATP-binding cassette sub-family C member 8

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion."
      Aguilar-Bryan L. , Nichols C.G. , Wechsler S.W. , Clement J.P. IV , Boyd A.E. III , Gonzalez G. , Herrera-Sosa H. , Nguy K. , Bryan J. , Nelson D.A.
      Science268:423-426(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM C)
      tissue: Pancreatic islet.
    2. 2.
      Faure C. , Partiseti M. , Gouhier C. , Graham D.
      Submitted (1996-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
      tissue: Pancreatic islet.
    3. 3.
      "Identification of two forms of sulfonylurea receptors (SUR 1A and SUR 1B) by means of polymerase chain reaction, subcloning, DNA sequencing and tissue distribution."
      Blache P. , Peyrollier K. , Gros L. , Bataille D.
      Submitted (1997-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B)
      tissue: Pancreatic islet.
    4. 4.
      Cao K. , Wang R.
      Submitted (2000-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
      tissue: Vascular smooth muscle.
    5. 5.
      "The high-affinity sulfonylurea receptor: distribution, glycosylation, purification, and immunoprecipitation of two forms from endocrine and neuroendocrine cell lines."
      Nelson D.A. , Bryan J. , Wechsler S. , Clement J.P. IV , Aguilar-Bryan L.
      Biochemistry35:14793-14799(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-10
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