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Index > Protein center > ABCC9(Gene name) > Human
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  • ABCC9 (Gene name),
  • ATP-binding cassette sub-family C member 9 (Protein name ),  ABCC9_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ABCC9(SUR2);
    Protein name:
    ATP-binding cassette sub-family C member 9;
    Alternative:
    Sulfonylurea receptor 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KIR6.2. KIR6.2 forms the channel pore while SUR2 is required for activation and regulation.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1549
    Sequence:
    50:
    MSLSFCGNNI | SSYNINDGVL | QNSCFVDALN | LVPHVFLLFI | TFPILFIGWG | 
    100:
    SQSSKVQIHH | NTWLHFPGHN | LRWILTFALL | FVHVCEIAEG | IVSDSRRESR | 
    150:
    HLHLFMPAVM | GFVATTTSIV | YYHNIETSNF | PKLLLALFLY | WVMAFITKTI | 
    200:
    KLVKYCQSGL | DISNLRFCIT | GMMVILNGLL | MAVEINVIRV | RRYVFFMNPQ | 
    250:
    KVKPPEDLQD | LGVRFLQPFV | NLLSKATYWW | MNTLIISAHK | KPIDLKAIGK | 
    300:
    LPIAMRAVTN | YVCLKDAYEE | QKKKVADHPN | RTPSIWLAMY | RAFGRPILLS | 
    350:
    STFRYLADLL | GFAGPLCISG | IVQRVNETQN | GTNNTTGISE | TLSSKEFLEN | 
    400:
    AYVLAVLLFL | ALILQRTFLQ | ASYYVTIETG | INLRGALLAM | IYNKILRLST | 
    450:
    SNLSMGEMTL | GQINNLVAIE | TNQLMWFLFL | CPNLWAMPVQ | IIMGVILLYN | 
    500:
    LLGSSALVGA | AVIVLLAPIQ | YFIATKLAEA | QKSTLDYSTE | RLKKTNEILK | 
    550:
    GIKLLKLYAW | EHIFCKSVEE | TRMKELSSLK | TFALYTSLSI | FMNAAIPIAA | 
    600:
    VLATFVTHAY | ASGNNLKPAE | AFASLSLFHI | LVTPLFLLST | VVRFAVKAII | 
    650:
    SVQKLNEFLL | SDEIGDDSWR | TGESSLPFES | CKKHTGVQPK | TINRKQPGRY | 
    700:
    HLDSYEQSTR | RLRPAETEDI | AIKVTNGYFS | WGSGLATLSN | IDIRIPTGQL | 
    750:
    TMIVGQVGCG | KSSLLLAILG | EMQTLEGKVH | WSNVNESEPS | FEATRSRNRY | 
    800:
    SVAYAAQKPW | LLNATVEENI | TFGSPFNKQR | YKAVTDACSL | QPDIDLLPFG | 
    850:
    DQTEIGERGI | NLSGGQRQRI | CVARALYQNT | NIVFLDDPFS | ALDIHLSDHL | 
    900:
    MQEGILKFLQ | DDKRTLVLVT | HKLQYLTHAD | WIIAMKDGSV | LREGTLKDIQ | 
    950:
    TKDVELYEHW | KTLMNRQDQE | LEKDMEADQT | TLERKTLRRA | MYSREAKAQM | 
    1000:
    EDEDEEEEEE | EDEDDNMSTV | MRLRTKMPWK | TCWRYLTSGG | FFLLILMIFS | 
    1050:
    KLLKHSVIVA | IDYWLATWTS | EYSINNTGKA | DQTYYVAGFS | ILCGAGIFLC | 
    1100:
    LVTSLTVEWM | GLTAAKNLHH | NLLNKIILGP | IRFFDTTPLG | LILNRFSADT | 
    1150:
    NIIDQHIPPT | LESLTRSTLL | CLSAIGMISY | ATPVFLVALL | PLGVAFYFIQ | 
    1200:
    KYFRVASKDL | QELDDSTQLP | LLCHFSETAE | GLTTIRAFRH | ETRFKQRMLE | 
    1250:
    LTDTNNIAYL | FLSAANRWLE | VRTDYLGACI | VLTASIASIS | GSSNSGLVGL | 
    1300:
    GLLYALTITN | YLNWVVRNLA | DLEVQMGAVK | KVNSFLTMES | ENYEGTMDPS | 
    1350:
    QVPEHWPQEG | EIKIHDLCVR | YENNLKPVLK | HVKAYIKPGQ | KVGICGRTGS | 
    1400:
    GKSSLSLAFF | RMVDIFDGKI | VIDGIDISKL | PLHTLRSRLS | IILQDPILFS | 
    1450:
    GSIRFNLDPE | CKCTDDRLWE | ALEIAQLKNM | VKSLPGGLDA | VVTEGGENFS | 
    1500:
    VGQRQLFCLA | RAFVRKSSIL | IMDEATASID | MATENILQKV | VMTAFADRTV | 
    1549:
    VTIAHRVSSI | MDAGLVLVFS | EGILVECDTV | PNLLAHKNGL | FSTLVMTNK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    Pfam:
    UniGene:
    MIM:
    String:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human ATP-binding cassette sub-family C member 9
    ELISA Kit for Human ATP-binding cassette sub-family C member 9
    ELISA Kit for Human ATP-binding cassette sub-family C member 9
    ELISA Kit for Human ATP-binding cassette sub-family C member 9
    CLIA Kit for Human ATP-binding cassette sub-family C member 9
    CLIA Kit for Human ATP-binding cassette sub-family C member 9
    CLIA Kit for Human ATP-binding cassette sub-family C member 9
    CLIA Kit for Human ATP-binding cassette sub-family C member 9
    Polyclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Polyclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Polyclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Polyclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Monoclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Monoclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Monoclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Monoclonal Antibody for Human ATP-binding cassette sub-family C member 9
    Protein for Human ATP-binding cassette sub-family C member 9
    Protein for Human ATP-binding cassette sub-family C member 9
    Protein for Human ATP-binding cassette sub-family C member 9
    Protein for Human ATP-binding cassette sub-family C member 9

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Toward understanding the assembly and structure of KATP channels."
      Aguilar-Bryan L. , Clement J.P. IV , Gonzalez G. , Kunjilwar K. , Babenko A. , Bryan J.
      Physiol. Rev.78:227-245(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS SUR2A AND SUR2B);REVIEW
    2. 2.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "Reconstituted human cardiac KATP channels: functional identity with the native channels from the sarcolemma of human ventricular cells."
      Babenko A.P. , Gonzalez G. , Aguilar-Bryan L. , Bryan J.
      Circ. Res.83:1132-1143(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE FUNCTION IN REGULATION OF SLEEP DURATION
    5. 5.
      "ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating."
      Bienengraeber M. , Olson T.M. , Selivanov V.A. , Kathmann E.C. , O'Cochlain F. , Gao F. , Karger A.B. , Ballew J.D. , Hodgson D.M. , Zingman L.V. , Pang Y.-P. , Alekseev A.E. , Terzic A.
      Nat. Genet.36:382-387(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMD1O THR-1513
    6. 6.
      "KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation."
      Olson T.M. , Alekseev A.E. , Moreau C. , Liu X.K. , Zingman L.V. , Miki T. , Seino S. , Asirvatham S.J. , Jahangir A. , Terzic A.
      Nat. Clin. Pract. Cardiovasc. Med.4:110-116(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ATFB12 ILE-1547;CHARACTERIZATION OF VARIANT ATFB12 ILE-1547
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HTOCD VAL-478; TYR-1043; GLN-1154 AND TRP-1154
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HTOCD TYR-60; GLU-207; CYS-380; LEU-432; PRO-1020; SER-1039; TYR-1054; HIS-1116; CYS-1116; GLN-1154 AND TRP-1154;CHARACTERIZATION OF VARIANTS HTOCD LEU-432; HIS-1116 AND GLN-1154
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