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Index > Protein center > ABCD2(Gene name) > Human
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  • ABCD2 (Gene name),
  • ATP-binding cassette sub-family D member 2 (Protein name ),  ABCD2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ABCD2(ALD1;ALDL1;ALDR;ALDRP);
    Protein name:
    ATP-binding cassette sub-family D member 2;
    Alternative:
    Adrenoleukodystrophy-related protein(hALDR);Adrenoleukodystrophy-like 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Can form heterodimers with ABCD1/ALD and ABCD3/PMP70. Dimerization is necessary to form an active transporter. Interacts with PEX19.
    Function:
    Probable transporter.
    Subcellular Location:
    Peroxisome membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    740
    Sequence:
    50:
    MTHMLNAAAD | RVKWTRSSAA | KRAACLVAAA | YALKTLYPII | GKRLKQSGHG | 
    100:
    KKKAAAYPAA | ENTEILHCTE | TICEKPSPGV | NADFFKQLLE | LRKILFPKLV | 
    150:
    TTETGWLCLH | SVALISRTFL | SIYVAGLDGK | IVKSIVEKKP | RTFIIKLIKW | 
    200:
    LMIAIPATFV | NSAIRYLECK | LALAFRTRLV | DHAYETYFTN | QTYYKVINMD | 
    250:
    GRLANPDQSL | TEDIMMFSQS | VAHLYSNLTK | PILDVMLTSY | TLIQTATSRG | 
    300:
    ASPIGPTLLA | GLVVYATAKV | LKACSPKFGK | LVAEEAHRKG | YLRYVHSRII | 
    350:
    ANVEEIAFYR | GHKVEMKQLQ | KSYKALADQM | NLILSKRLWY | IMIEQFLMKY | 
    400:
    VWSSSGLIMV | AIPIITATGF | ADGEDGQKQV | MVSERTEAFT | TARNLLASGA | 
    450:
    DAIERIMSSY | KEVTELAGYT | ARVYNMFWVF | DEVKRGIYKR | TAVIQESESH | 
    500:
    SKNGAKVELP | LSDTLAIKGK | VIDVDHGIIC | ENVPIITPAG | EVVASRLNFK | 
    550:
    VEEGMHLLIT | GPNGCGKSSL | FRILSGLWPV | YEGVLYKPPP | QHMFYIPQRP | 
    600:
    YMSLGSLRDQ | VIYPDSVDDM | HDKGYTDQDL | ERILHNVHLY | HIVQREGGWD | 
    650:
    AVMDWKDVLS | GGEKQRMGMA | RMFYHKPKYA | LLDECTSAVS | IDVEGKIFQA | 
    700:
    AKGAGISLLS | ITHRPSLWKY | HTHLLQFDGE | GGWRFEQLDT | AIRLTLSEEK | 
    740:
    QKLESQLAGI | PKMQQRLNEL | CKILGEDSVL | KTIKNEDETS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    MIM:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human ATP-binding cassette sub-family D member 2
    ELISA Kit for Human ATP-binding cassette sub-family D member 2
    ELISA Kit for Human ATP-binding cassette sub-family D member 2
    CLIA Kit for Human ATP-binding cassette sub-family D member 2
    CLIA Kit for Human ATP-binding cassette sub-family D member 2
    CLIA Kit for Human ATP-binding cassette sub-family D member 2
    Polyclonal Antibody for Human ATP-binding cassette sub-family D member 2
    Polyclonal Antibody for Human ATP-binding cassette sub-family D member 2
    Polyclonal Antibody for Human ATP-binding cassette sub-family D member 2
    Monoclonal Antibody for Human ATP-binding cassette sub-family D member 2
    Monoclonal Antibody for Human ATP-binding cassette sub-family D member 2
    Monoclonal Antibody for Human ATP-binding cassette sub-family D member 2
    Protein for Human ATP-binding cassette sub-family D member 2
    Protein for Human ATP-binding cassette sub-family D member 2
    Protein for Human ATP-binding cassette sub-family D member 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern."
      Lombard-Platet G. , Savary S. , Sarde C.-O. , Mandel J.-L. , Chimini G.
      Proc. Natl. Acad. Sci. U.S.A.93:1265-1269(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter."
      Holzinger A. , Kammerer S. , Berger J. , Roscher A.A.
      Biochem. Biophys. Res. Commun.239:261-264(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Full length cDNA cloning, promoter sequence, and genomic organization of the human adrenoleukodystrophy related (ALDR) gene functionally redundant to the gene responsible for X-linked adrenoleukodystrophy."
      Holzinger A. , Mayerhofer P. , Berger J. , Lichtner P. , Kammerer S. , Roscher A.A.
      Biochem. Biophys. Res. Commun.258:436-442(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];CHARACTERIZATION
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Trachea.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    7. 7.
      "Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters."
      Liu L.X. , Janvier K. , Berteaux-Lecellier V. , Cartier N. , Benarous R. , Aubourg P.
      J. Biol. Chem.274:32738-32743(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    8. 8.
      "Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p."
      Gloeckner C.J. , Mayerhofer P.U. , Landgraf P. , Muntau A.C. , Holzinger A. , Gerber J.-K. , Kammerer S. , Adamski J. , Roscher A.A.
      Biochem. Biophys. Res. Commun.271:144-150(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PEX19
      tissue: Brain.
    9. 9.
      "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis."
      Sacksteder K.A. , Jones J.M. , South S.T. , Li X. , Liu Y. , Gould S.J.
      J. Cell Biol.148:931-944(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PEX19
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LYS-244
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