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Index > Protein center > ABCD3(Gene name) > Human
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  • ABCD3 (Gene name),
  • ATP-binding cassette sub-family D member 3 (Protein name ),  ABCD3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ABCD3(PMP70;PXMP1);
    Protein name:
    ATP-binding cassette sub-family D member 3;
    Alternative:
    70 kDa peroxisomal membrane protein(PMP70);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Can form heterodimers with ABCD1/ALD and ABCD2/ALDR. Dimerization is necessary to form an active transporter. Interacts with PEX19.
    Function:
    Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
    Subcellular Location:
    Peroxisome membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    659
    Sequence:
    50:
    MAAFSKYLTA | RNSSLAGAAF | LLLCLLHKRR | RALGLHGKKS | GKPPLQNNEK | 
    100:
    EGKKERAVVD | KVFFSRLIQI | LKIMVPRTFC | KETGYLVLIA | VMLVSRTYCD | 
    150:
    VWMIQNGTLI | ESGIIGRSRK | DFKRYLLNFI | AAMPLISLVN | NFLKYGLNEL | 
    200:
    KLCFRVRLTK | YLYEEYLQAF | TYYKMGNLDN | RIANPDQLLT | QDVEKFCNSV | 
    250:
    VDLYSNLSKP | FLDIVLYIFK | LTSAIGAQGP | ASMMAYLVVS | GLFLTRLRRP | 
    300:
    IGKMTITEQK | YEGEYRYVNS | RLITNSEEIA | FYNGNKREKQ | TVHSVFRKLV | 
    350:
    EHLHNFILFR | FSMGFIDSII | AKYLATVVGY | LVVSRPFLDL | SHPRHLKSTH | 
    400:
    SELLEDYYQS | GRMLLRMSQA | LGRIVLAGRE | MTRLAGFTAR | ITELMQVLKD | 
    450:
    LNHGKYERTM | VSQQEKGIEG | VQVIPLIPGA | GEIIIADNII | KFDHVPLATP | 
    500:
    NGDVLIRDLN | FEVRSGANVL | ICGPNGCGKS | SLFRVLGELW | PLFGGRLTKP | 
    550:
    ERGKLFYVPQ | RPYMTLGTLR | DQVIYPDGRE | DQKRKGISDL | VLKEYLDNVQ | 
    600:
    LGHILEREGG | WDSVQDWMDV | LSGGEKQRMA | MARLFYHKPQ | FAILDECTSA | 
    650:
    VSVDVEGYIY | SHCRKVGITL | FTVSHRKSLW | KHHEYYLHMD | GRGNYEFKQI | 
    659:
    TEDTVEFGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    MIM:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human ATP-binding cassette sub-family D member 3
    ELISA Kit for Human ATP-binding cassette sub-family D member 3
    ELISA Kit for Human ATP-binding cassette sub-family D member 3
    CLIA Kit for Human ATP-binding cassette sub-family D member 3
    CLIA Kit for Human ATP-binding cassette sub-family D member 3
    CLIA Kit for Human ATP-binding cassette sub-family D member 3
    Polyclonal Antibody for Human ATP-binding cassette sub-family D member 3
    Polyclonal Antibody for Human ATP-binding cassette sub-family D member 3
    Polyclonal Antibody for Human ATP-binding cassette sub-family D member 3
    Monoclonal Antibody for Human ATP-binding cassette sub-family D member 3
    Monoclonal Antibody for Human ATP-binding cassette sub-family D member 3
    Monoclonal Antibody for Human ATP-binding cassette sub-family D member 3
    Protein for Human ATP-binding cassette sub-family D member 3
    Protein for Human ATP-binding cassette sub-family D member 3
    Protein for Human ATP-binding cassette sub-family D member 3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome."
      Gaertner J. , Moser H. , Valle D.
      Nat. Genet.1:16-23(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ASP-17
      tissue: Liver.
    2. 2.
      "Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters."
      Kamijo K. , Kamijo T. , Ueno I. , Osumi T. , Hashimoto T.
      Biochim. Biophys. Acta1129:323-327(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Liver.
    3. 3.
      "Genomic organization of the 70-kDa peroxisomal membrane protein gene (PXMP1)."
      Gaertner J. , Jimenez-Sanchez G. , Roerig P. , Valle D.
      Genomics48:203-208(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
      tissue: Brain.
      tissue: Lung.
    8. 8.
      "Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters."
      Liu L.X. , Janvier K. , Berteaux-Lecellier V. , Cartier N. , Benarous R. , Aubourg P.
      J. Biol. Chem.274:32738-32743(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    9. 9.
      "Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p."
      Gloeckner C.J. , Mayerhofer P.U. , Landgraf P. , Muntau A.C. , Holzinger A. , Gerber J.-K. , Kammerer S. , Adamski J. , Roscher A.A.
      Biochem. Biophys. Res. Commun.271:144-150(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PEX19
      tissue: Brain.
    10. 10.
      "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis."
      Sacksteder K.A. , Jones J.M. , South S.T. , Li X. , Liu Y. , Gould S.J.
      J. Cell Biol.148:931-944(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH PEX19
    11. 11.
      "Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters."
      Roerig P. , Mayerhofer P. , Holzinger A. , Gaertner J.
      FEBS Lett.492:66-72(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF GLY-478 AND SER-572
    12. 12.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-260 AND LYS-399;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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