ABCE1 ELISA Kit for Human(Homo sapiens) | EIAab.comABCE1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ABCE1(Gene name) > Human

ABCE1 (Gene name),

ATP-binding cassette sub-family E member 1 (Protein name ), ABCE1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ABCE1(OK/SW-cl.40;RLI;RNASEL1;RNASELI;RNS4I);

Protein name:

ATP-binding cassette sub-family E member 1;

Alternative:

HuHP68;2'-5'-oligoadenylate-binding protein;Ribonuclease 4 inhibitor(RNS4I);RNase L inhibitor;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Probably heterodimerizes with RNASEL; this interaction inhibits the RNASEL. Associates with HIV-1 Vif and HIV-1, HIV-2 and SIV Gag proteins.

Function:

Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.

Subcellular Location:

Cytoplasm Mitochondrion Localized to clusters of virus formation at the plasma membrane.

Protein Attributes:

Sequence length:

599

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

599:

LLAGMNKFLS | QLEITFRRDP | NNYRPRINKL | NSIKDVEQKK | SGNYFFLDD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P61221

STRING:

9606.ENSP00000296577

Pfam:

PF00005

UniGene:

Hs.12013

SMR:

P61221

MIM:

601213

KEGG:

hsa:6059

Uniprot:

P61221

FOR

ELISA Kit for Human ATP-binding cassette sub-family E member 1

CLIA Kit for Human ATP-binding cassette sub-family E member 1

Polyclonal Antibody for Human ATP-binding cassette sub-family E member 1

Monoclonal Antibody for Human ATP-binding cassette sub-family E member 1

Protein for Human ATP-binding cassette sub-family E member 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and characterization of a RNase L inhibitor. A new component of the interferon-regulated 2-5A pathway."
Bisbal C. , Martinand C. , Silhol M. , Lebleu B. , Salehzada T.
J. Biol. Chem.270:13308-13317(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION;INTERACTION WITH RNASEL
2.

"Chromosomal localization and expression pattern of the RNase L inhibitor gene."
Aubry F. , Mattei M.-G. , Barque J.-P. , Galibert F.
FEBS Lett.381:135-139(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Identification of immuno-peptidmics that are recognized by tumor-reactive CTL generated from TIL of colon cancer patients."
Shichijo S. , Itoh K.
Submitted (2001-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Colon adenocarcinoma.
4.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

SeattleSNPs variation discovery resource
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Duodenum.
tissue: Uterus.
7.

"RNase L inhibitor (RLI) antisense constructions block partially the down regulation of the 2-5A/RNase L pathway in encephalomyocarditis-virus-(EMCV)-infected cells."
Martinand C. , Salehzada T. , Silhol M. , Lebleu B. , Bisbal C.
Eur. J. Biochem.254:248-255(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY EMCV;FUNCTION
8.

"RNase L inhibitor is induced during human immunodeficiency virus type 1 infection and down regulates the 2-5A/RNase L pathway in human T cells."
Martinand C. , Montavon C. , Salehzada T. , Silhol M. , Lebleu B. , Bisbal C.
J. Virol.73:290-296(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY HIV-1;FUNCTION
9.

"The 2-5A/RNase L/RNase L inhibitor (RNI) pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cells."
Le Roy F. , Bisbal C. , Silhol M. , Martinand C. , Lebleu B. , Salehzada T.
J. Biol. Chem.276:48473-48482(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;FUNCTION
10.

"Identification of a host protein essential for assembly of immature HIV-1 capsids."
Zimmerman C. , Klein K.C. , Kiser P.K. , Singh A.R. , Firestein B.L. , Riba S.C. , Lingappa J.R.
Nature415:88-92(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 VIF AND GAG PROTEINS
11.

"Conservation of a stepwise, energy-sensitive pathway involving HP68 for assembly of primate lentivirus capsids in cells."
Dooher J.E. , Lingappa J.R.
J. Virol.78:1645-1656(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-2 AND SIV GAG PROTEINS
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Detection and validation of non-synonymous coding SNPs from orthogonal analysis of shotgun proteomics data."
Bunger M.K. , Cargile B.J. , Sevinsky J.R. , Deyanova E. , Yates N.A. , Hendrickson R.C. , Stephenson J.L. Jr.
J. Proteome Res.6:2331-2340(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CYS-489;IDENTIFICATION BY MASS SPECTROMETRY

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