ABCG5 ELISA Kit for Human(Homo sapiens) | EIAab.comABCG5 ELISA Kit for Human(Homo sapiens)

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ABCG5 (Gene name),

ATP-binding cassette sub-family G member 5 (Protein name ), ABCG5_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ABCG5;

Protein name:

ATP-binding cassette sub-family G member 5;

Alternative:

Sterolin-1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

May form heterodimers with ABCG8 or be tightly coupled to ABCG8 along a pathway regulating diatery-sterol absorption and excretion.

Function:

Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

651

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

651:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF01061

UniGene:

Hs.132992

STRING:

9606.ENSP00000260645

KEGG:

hsa:64240

MIM:

210250

SMR:

Q9H222

String:

Q9H222

Uniprot:

Q9H222

FOR

ELISA Kit for Human ATP-binding cassette sub-family G member 5

CLIA Kit for Human ATP-binding cassette sub-family G member 5

Polyclonal Antibody for Human ATP-binding cassette sub-family G member 5

Monoclonal Antibody for Human ATP-binding cassette sub-family G member 5

Protein for Human ATP-binding cassette sub-family G member 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters."
Berge K.E. , Tian H. , Graf G.A. , Yu L. , Grishin N.V. , Schultz J. , Kwiterovich P. , Shan B. , Barnes R. , Hobbs H.H.
Science290:1771-1775(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLU-604
tissue: Liver.
2.

"Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption."
Lee M.-H. , Lu K. , Hazard S. , Yu H. , Shulenin S. , Hidaka H. , Kojima H. , Allikmets R. , Sakuma N. , Pegoraro R. , Srivastava A.K. , Salen G. , Dean M. , Patel S.B.
Nat. Genet.27:79-83(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS STSL HIS-389; HIS-419 AND PRO-419;VARIANT GLU-604
tissue: Liver.
3.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
6.

"Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively."
Lu K. , Lee M.-H. , Hazard S. , Brooks-Wilson A. , Hidaka H. , Kojima H. , Ose L. , Stalenhoef A.F.H. , Mietinnen T. , Bjorkhem I. , Bruckert E. , Pandya A. , Brewer H.B. Jr. , Salen G. , Dean M. , Srivastava A.K. , Patel S.B.
Am. J. Hum. Genet.69:278-290(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-88 (ISOFORM 1);VARIANTS STSL GLN-146; HIS-389; PRO-419; HIS-419 AND SER-550;VARIANT GLU-604
7.

"Role of ABCG1 and other ABCG family members in lipid metabolism."
Schmitz G. , Langmann T. , Heimerl S.
J. Lipid Res.42:1513-1520(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
8.

"Mutations in ATP-cassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia."
Hubacek J.A. , Berge K.E. , Cohen J.C. , Hobbs H.H.
Hum. Mutat.18:359-360(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT STSL LYS-437;VARIANTS VAL-523; TYR-600; GLU-604 AND VAL-622

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