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Index > Protein center > Apobec3(Gene name) > Mouse
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  • Apobec3 (Gene name),
  • DNA dC->dU-editing enzyme APOBEC-3 (Protein name ),  ABEC3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Apobec3;
    Protein name:
    DNA dC->dU-editing enzyme APOBEC-3;
    Alternative:
    CEM-15(CEM15);Apolipoprotein B mRNA-editing complex 3(Arp3);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Has a DNA cytidine deaminase activity. Host cellular restriction factor that may have antiviral activities against exogenous and endogenous viruses, as well as retrotransposons.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    429
    Sequence:
    50:
    MGPFCLGCSH | RKCYSPIRNL | ISQETFKFHF | KNLGYAKGRK | DTFLCYEVTR | 
    100:
    KDCDSPVSLH | HGVFKNKDNI | HAEICFLYWF | HDKVLKVLSP | REEFKITWYM | 
    150:
    SWSPCFECAE | QIVRFLATHH | NLSLDIFSSR | LYNVQDPETQ | QNLCRLVQEG | 
    200:
    AQVAAMDLYE | FKKCWKKFVD | NGGRRFRPWK | RLLTNFRYQD | SKLQEILRPC | 
    250:
    YIPVPSSSSS | TLSNICLTKG | LPETRFCVEG | RRMDPLSEEE | FYSQFYNQRV | 
    300:
    KHLCYYHRMK | PYLCYQLEQF | NGQAPLKGCL | LSEKGKQHAE | ILFLDKIRSM | 
    350:
    ELSQVTITCY | LTWSPCPNCA | WQLAAFKRDR | PDLILHIYTS | RLYFHWKRPF | 
    400:
    QKGLCSLWQS | GILVDVMDLP | QFTDCWTNFV | NPKRPFWPWK | GLEIISRRTQ | 
    429:
    RRLRRIKESW | GLQDLVNDFG | NLQLGPPMS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DNA dC->dU-editing enzyme APOBEC-3
    ELISA Kit for Mouse DNA dC->dU-editing enzyme APOBEC-3
    CLIA Kit for Mouse DNA dC->dU-editing enzyme APOBEC-3
    CLIA Kit for Mouse DNA dC->dU-editing enzyme APOBEC-3
    Polyclonal Antibody for Mouse DNA dC->dU-editing enzyme APOBEC-3
    Polyclonal Antibody for Mouse DNA dC->dU-editing enzyme APOBEC-3
    Monoclonal Antibody for Mouse DNA dC->dU-editing enzyme APOBEC-3
    Monoclonal Antibody for Mouse DNA dC->dU-editing enzyme APOBEC-3
    Protein for Mouse DNA dC->dU-editing enzyme APOBEC-3
    Protein for Mouse DNA dC->dU-editing enzyme APOBEC-3

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3);VARIANTS ARG-34; 37-ILE-ASP-38; 112-VAL-LEU-113; 134-ILE-ARG-135; ASN-139; LYS-181; 233-VAL-HIS-LEU-235; GLY-258; ILE-306 AND HIS-404
      strain: C57BL/6J.
      tissue: Hippocampus.
      tissue: Retina.
    2. 2.
      Mariani R. , Landau N.R.
      Submitted (2004-02) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORM 4);VARIANTS
      strain: C57BL/6J.
      tissue: Spleen.
    3. 3.
      "Initial sequencing and comparative analysis of the mouse genome."
      Waterston R.H. , Lindblad-Toh K. , Birney E. , Rogers J. , Abril J.F. , Agarwal P. , Agarwala R. , Ainscough R. , Alexandersson M. , An P. , Antonarakis S.E. , Attwood J. , Baertsch R. , Bailey J. , Barlow K. , Beck S. , Berry E. , Birren B. , more...
      Nature420:520-562(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS ARG-34; 37-ILE-ASP-38; 112-VAL-LEU-113; 134-ILE-ARG-135; ASN-139; LYS-181; 233-VAL-HIS-LEU-235; GLY-258; ILE-306 AND HIS-404
      tissue: Mammary tumor.
    5. 5.
      "Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif."
      Mariani R. , Chen D. , Schroefelbauer B. , Navarro F. , Koenig R. , Bollman B. , Muenk C. , Nymark-McMahon H. , Landau N.R.
      Cell114:21-31(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DNA C TO U EDITING ACTIVITY;TISSUE SPECIFICITY
    6. 6.
      "APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons."
      Chen H. , Lilley C.E. , Yu Q. , Lee D.V. , Chou J. , Narvaiza I. , Landau N.R. , Weitzman M.D.
      Curr. Biol.16:480-485(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN RETROTRANSPOSITION;SUBCELLULAR LOCATION
    7. 7.
      "Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains."
      Hakata Y. , Landau N.R.
      J. Biol. Chem.281:36624-36631(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN CMP/DCMP DEAMINASE ZINC-BINDING;SUBUNIT;MUTAGENESIS OF GLU-73 AND GLU-290
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN SFV RESTRICTION
    9. 9.
      "APOBEC3 inhibits mouse mammary tumour virus replication in vivo."
      Okeoma C.M. , Lovsin N. , Peterlin B.M. , Ross S.R.
      Nature445:927-930(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MMTV RESTRICTION;INTERACTION WITH MMTV NUCLEOCAPSID PROTEIN P14
    10. 10.
      "The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements."
      Chiu Y.L. , Greene W.C.
      Annu. Rev. Immunol.26:317-353(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    11. 11.
      "Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo."
      Takeda E. , Tsuji-Kawahara S. , Sakamoto M. , Langlois M.A. , Neuberger M.S. , Rada C. , Miyazawa M.
      J. Virol.82:10998-11008(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN FRMLV RESTRICTION
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